Zobrazeno 1 - 10
of 174
pro vyhledávání: '"José Miguel Vela"'
Autor:
José Miguel Vela, Mauro Daccordi
Publikováno v:
Natural History Sciences, Vol 10, Iss s1 (2023)
The endophallus of Timarcha kiesenwetteri ssp. sagrensis is herein described for the first time. Its morphology is simple. It has a long basal lobe and a large medial lobe which narrows progressively to a small apical diverticulum. Timarcha kiesenwet
Externí odkaz:
https://doaj.org/article/6929f0c950b74271b6ef9b6107b25f4b
Autor:
Alba Vidal-Torres, Begoña Fernández-Pastor, Mónica García, Eva Ayet, Anna Cabot, Javier Burgueño, Xavier Monroy, Bertrand Aubel, Xavier Codony, Luz Romero, Rosalía Pascual, Maria Teresa Serafini, Gregorio Encina, Carmen Almansa, Daniel Zamanillo, Manuel Merlos, José Miguel Vela
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 1, Pp 82-99 (2023)
Opioids are the most effective painkillers, but their benefit-risk balance often hinder their therapeutic use. WLB-73502 is a dual, bispecific compound that binds sigma-1 (S1R) and mu-opioid (MOR) receptors. WLB-73502 is an antagonist at the S1R. It
Externí odkaz:
https://doaj.org/article/5db3e49f2136462cbd27dfe08f2a9b36
Autor:
Beltrán Álvarez-Pérez, Meritxell Deulofeu, Judit Homs, Manuel Merlos, José Miguel Vela, Enrique Verdú, Pere Boadas-Vaello
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Nociplastic pain arises from altered nociception despite no clear evidence of tissue or somatosensory system damage, and fibromyalgia syndrome can be highlighted as a prototype of this chronic pain subtype. Currently, there is a lack of effe
Externí odkaz:
https://doaj.org/article/f9be21ec50514203b047202a9b064990
Autor:
Eduardo Torres, Carlos Álvarez-Acosta, Modesto del Pino, María Eva Wong, Juan Ramón Boyero, Estrella Hernández-Suárez, José Miguel Vela
Publikováno v:
Agronomy, Vol 13, Iss 3, p 668 (2023)
The Persea mite, Oligonychus perseae Tuttle, Baker & Abbatiello (Acari: Tetranychidae), is an economically important foliar pest of avocados in Spain. The effects of this mite on the foliar damage, production losses and economic impact were assessed
Externí odkaz:
https://doaj.org/article/e6e3b6d5144a47dfab6ea1a45309be0c
Publikováno v:
ZooKeys, Vol 986, Iss , Pp 55-80 (2020)
Linnaeus described five species presently included in the genus Timarcha: Chrysomela goettingensis, Tenebrio caeruleus, Tenebrio laevigatus, Tenebrio latipes, and Tenebrio rugosus. After a study of the relevant material, the identity of these species
Externí odkaz:
https://doaj.org/article/776a2b52dea7400da54ee5db6a567950
Autor:
Sílvia Castany, Anna Bagó-Mas, José Miguel Vela, Enrique Verdú, Karolina Bretová, Viktorie Svobodová, Petr Dubový, Pere Boadas-Vaello
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 1761 (2023)
Central neuropathic pain is not only characterized by reflexive pain responses, but also emotional or affective nonreflexive pain responses, especially in women. Some pieces of evidence suggest that the activation of the neuroimmune system may be con
Externí odkaz:
https://doaj.org/article/beb4a2a7b6a8481a8036a484013756ce
Autor:
Beltrán Álvarez-Pérez, Anna Bagó-Mas, Meritxell Deulofeu, José Miguel Vela, Manuel Merlos, Enrique Verdú, Pere Boadas-Vaello
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11933 (2022)
Sigma-1 receptor (σ1R) ligands have been shown to be effective at relieving neuropathic and inflammatory pain, but have not yet been tested in experimental models of fibromyalgia. The objective of this study was to evaluate the effect of a σ1R anta
Externí odkaz:
https://doaj.org/article/9d3d78c46c934319987214d52905b19a
Autor:
Baiba Svalbe, Baiba Zvejniece, Gundega Stelfa, Karlis Vilks, Edijs Vavers, José Miguel Vela, Maija Dambrova, Liga Zvejniece
Publikováno v:
Biomedicines, Vol 10, Iss 7, p 1572 (2022)
Sigma-1 receptor (Sig1R) has been proposed as a therapeutic target for neurological, neurodegenerative, and psychiatric disorders, including depression and anxiety. Identifying metabolites that are affected by Sig1R absence and cross-referencing them
Externí odkaz:
https://doaj.org/article/4732e11896264421963d18e2bf0d429e
Autor:
José Miguel Vela
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Outbreaks of emerging infections, such as COVID-19 pandemic especially, confront health professionals with the unique challenge of treating patients. With no time to discover new drugs, repurposing of approved drugs or in clinical development is like
Externí odkaz:
https://doaj.org/article/85bf918e9ebf4fbcbe571c29c859420f
Publikováno v:
European Journal of Taxonomy, Iss 630 (2020)
Historically the taxonomy of the genus Timarcha has been, and continues to be, quite confusing and largely erroneous. The confusion is mainly due to the absence of reliable traits that aid in precise identification; the lack of study of types at spec
Externí odkaz:
https://doaj.org/article/679ba5e207af4e9ab880ff99ae8ee90d