Zobrazeno 1 - 10
of 10
pro vyhledávání: '"José Miguel Fernández-Justel"'
Autor:
Ricardo Almeida, José Miguel Fernández-Justel, Cristina Santa-María, Jean-Charles Cadoret, Laura Cano-Aroca, Rodrigo Lombraña, Gonzalo Herranz, Alessandra Agresti, María Gómez
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
The maintenance of chromatin integrity during replication is critical for cell viability. Here the authors study how dividing cells respond to alterations in chromatin structure and find that these elicit a range of responses in the dynamics of DNA r
Externí odkaz:
https://doaj.org/article/399d7ceb0c43497db1da7ece90fc06c8
Autor:
Rodrigo Lombraña, Alba Álvarez, José Miguel Fernández-Justel, Ricardo Almeida, César Poza-Carrión, Fábia Gomes, Arturo Calzada, José María Requena, María Gómez
Publikováno v:
Cell Reports, Vol 16, Iss 6, Pp 1774-1786 (2016)
Faithful inheritance of eukaryotic genomes requires the orchestrated activation of multiple DNA replication origins (ORIs). Although origin firing is mechanistically conserved, how origins are specified and selected for activation varies across diffe
Externí odkaz:
https://doaj.org/article/735d1240a7a04d1c9d6fae8a4de76c0d
Autor:
Esperanza Hernández-Carralero, Elisa Cabrera, Gara Rodríguez-Torres, Yeray Hernández-Reyes, Abhay N Singh, Cristina Santa-María, José Miguel Fernández-Justel, Roel C Janssens, Jurgen A Marteijn, Bernd O Evert, Niels Mailand, María Gómez, Kristijan Ramadan, Veronique A J Smits, Raimundo Freire
Publikováno v:
Hernández-Carralero, E, Cabrera, E, Rodríguez-Torres, G, Hernández-Reyes, Y, Singh, A N, Santa-María, C, Fernández-Justel, J M, Janssens, R C, Marteijn, J A, Evert, B O, Mailand, N, Gómez, M, Ramadan, K, Smits, V A J & Freire, R 2023, ' ATXN3 controls DNA replication and transcription by regulating chromatin structure ', Nucleic Acids Research, vol. 51, no. 11, pp. 5396–5413 . https://doi.org/10.1093/nar/gkad212
The deubiquitinating enzyme Ataxin-3 (ATXN3) contains a polyglutamine (PolyQ) region, the expansion of which causes spinocerebellar ataxia type-3 (SCA3). ATXN3 has multiple functions, such as regulating transcription or controlling genomic stability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5aa7d5c4a33687a0e2797bef5f2c754
https://doi.org/10.1093/nar/gkad212
https://doi.org/10.1093/nar/gkad212
Autor:
Alicia Gallego, José Miguel Fernández-Justel, Sara Martín-Vírgala, Magdalena M. Maslon, María Gómez
Publikováno v:
Genes; Volume 13; Issue 9; Pages: 1652
N6-methyladenosine modification (m6A) fine-tunes RNA fate in a variety of ways, thus regulating multiple fundamental biological processes. m6A writers bind to chromatin and interact with RNA polymerase II (RNAPII) during transcription. To evaluate ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5201cfa812ec779d2b87cadf368b515b
Autor:
José Miguel Fernández-Justel, Cristina Santa-María, Sara Martín-Vírgala, Shreya Ramesh, Alberto Ferrera-Lagoa, Mónica Salinas-Pena, Javier Isoler-Alcaraz, Magdalena M. Maslon, Albert Jordan, Javier F. Cáceres, María Gómez
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Fernández-Justel, J M, Santa-María, C, Martín-Vírgala, S, Ramesh, S, Ferrera-Lagoa, A, Salinas-Pena, M, Isoler-Alcaraz, J, Maslon, M, Jordan, A, Caceres, J F & Gómez, M 2022, ' Histone H1 regulates non-coding RNA turnover on chromatin in a m6A-dependent manner ', Cell Reports, vol. 40, no. 11 . https://doi.org/10.1016/j.celrep.2022.111329
instname
Fernández-Justel, J M, Santa-María, C, Martín-Vírgala, S, Ramesh, S, Ferrera-Lagoa, A, Salinas-Pena, M, Isoler-Alcaraz, J, Maslon, M, Jordan, A, Caceres, J F & Gómez, M 2022, ' Histone H1 regulates non-coding RNA turnover on chromatin in a m6A-dependent manner ', Cell Reports, vol. 40, no. 11 . https://doi.org/10.1016/j.celrep.2022.111329
Linker histones are highly abundant chromatin-associated proteins with well-established structural roles in chromatin and as general transcriptional repressors. In addition, it has been long proposed that histone H1 exerts context-specific effects on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97bfda3c2c25f75e09737a103cc8983f
http://hdl.handle.net/10261/281158
http://hdl.handle.net/10261/281158
Autor:
Luisa Statello, José Miguel Fernandez-Justel, Jovanna González, Marta Montes, Alessia Ranieri, Enrique Goñi, Aina M. Mas, Maite Huarte
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
ABSTRACT Besides the well-characterized protein network involved in the replication stress response, several regulatory RNAs have been shown to play a role in this critical process. However, it has remained elusive whether they act locally at the str
Externí odkaz:
https://doaj.org/article/4c4b5d904e5b436e8e1b2fe597ae8501
Autor:
Graña-Castro O, Juan Méndez, Fatima Al-Shahrour, Carrillo-de Santa Pau E, Maria Rigau, Pancaldi, Manuel Gómez, Alfonso Valencia, David G. Pisano, Rodríguez-Acebes S, Jodkowska K, Ricardo Almeida, Rubio-Camarillo M, José Miguel Fernández-Justel
In mammalian cells, chromosomal replication starts at thousands of origins at which replisomes are assembled and bidirectional DNA synthesis is established. The slowdown of DNA polymerases at endogenous or exogenous obstacles triggers the activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69fd29f77e94291badcab0f76848aab7
https://doi.org/10.1101/644971
https://doi.org/10.1101/644971
Evolution of Replication Origins in Vertebrate Genomes: Rapid Turnover Despite Selective Constraints
Autor:
Marie-Noëlle Prioleau, Caroline Brossas, Marc Laurent, José Miguel Fernández-Justel, María Gómez, Franck Picard, Florian Massip, Laurent Duret
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2019, 47 (10), pp.5114-5125. ⟨10.1093/nar/gkz182⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nucleic Acids Research, 2019, 47 (10), pp.5114-5125. ⟨10.1093/nar/gkz182⟩
Nucleic Acids Research, Oxford University Press, 2019, 47 (10), pp.5114-5125. ⟨10.1093/nar/gkz182⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nucleic Acids Research, 2019, 47 (10), pp.5114-5125. ⟨10.1093/nar/gkz182⟩
The replication program of vertebrate genomes is driven by the chromosomal distribution and timing of activation of tens of thousands of replication origins. Genome-wide studies have shown the association of origins with promoters and CpG islands, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f26319db5e94600a802a8d5eb7c93fc7
https://doi.org/10.1101/411470
https://doi.org/10.1101/411470
Autor:
Alessandra Agresti, Laura Cano-Aroca, Ricardo Almeida, Rodrigo Lombraña, Gonzalo Herranz, María Gómez, Cristina Santa-María, Jean-Charles Cadoret, José Miguel Fernández-Justel
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Chromatin is the template for the basic processes of replication and transcription, making the maintenance of chromosomal integrity critical for cell viability. To elucidate how dividing cells respond to alterations in chromatin structure, here we an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a69b09d88a849a7c7b6e7d8346e52c2
https://pubmed.ncbi.nlm.nih.gov/29686321
https://pubmed.ncbi.nlm.nih.gov/29686321
Autor:
Arturo Calzada, Fábia Gomes, Alba Garcimartín Álvarez, Jose M. Requena, César Poza-Carrión, José Miguel Fernández-Justel, María Gómez, Ricardo Almeida, Rodrigo Lombraña
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Cell Reports, Vol 16, Iss 6, Pp 1774-1786 (2016)
instname
Cell Reports, Vol 16, Iss 6, Pp 1774-1786 (2016)
Faithful inheritance of eukaryotic genomes requires the orchestrated activation of multiple DNA replication origins (ORIs). Although origin firing is mechanistically conserved, how origins are specified and selected for activation varies across diffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1237f222cea3ac1f42ae4dce4937366f
http://hdl.handle.net/10261/152216
http://hdl.handle.net/10261/152216