Zobrazeno 1 - 3
of 3
pro vyhledávání: '"José Miguel Côdesso"'
Autor:
Rebekah Koppenol, André Conceição, Adriana Marcelo, Sandra Tomé, José-Miguel Côdesso, Liliana Mendonça, Luis Pereira de Almeida, Carlos Matos, Clévio Nóbrega
Polylgutamine (polyQ) diseases are a group of neurodegenerative disorders caused by abnormal expansion of CAG repeat tracts in the codifying regions of nine, otherwise unrelated, genes. While the protein products of these genes are suggested to play
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2d824972a405850a92f304bda104421
https://doi.org/10.21203/rs.3.rs-668663/v2
https://doi.org/10.21203/rs.3.rs-668663/v2
Autor:
Rebekah Koppenol, André Conceição, Inês T Afonso, Ricardo Afonso-Reis, Rafael G Costa, Sandra Tomé, Diogo Teixeira, Joana Pinto da Silva, José Miguel Côdesso, David V C Brito, Liliana Mendonça, Adriana Marcelo, Luís Pereira de Almeida, Carlos A Matos, Clévio Nóbrega
Publikováno v:
Brain : a journal of neurology.
Koppenol et al. show that overexpression of G3BP1 in cell models of SCA2 and SCA3 leads to a reduction in ataxin-2 and ataxin-3 aggregation. G3BP1 lentiviral delivery reduces motor deficits and neuropathology in preclinical models, suggesting that G3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3af63acee90918998467f5586a1a267d
https://pubmed.ncbi.nlm.nih.gov/36511898
https://pubmed.ncbi.nlm.nih.gov/36511898
Autor:
Clévio Nóbrega, André Conceição, Sandra Tomé, Rebekah Koppenol, Carlos A. Matos, Adriana Marcelo, Liliana Mendonça, Luís Pereira de Almeida, José-Miguel Côdesso
Polyglutamine (polyQ) diseases are a group of 9 rare neurodegenerative disorders caused by an abnormal expansion of the CAG trinucleotide in the codifying regions of the respective disease-associated gene. The trinucleotide abnormal expansion leads t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b4e55ec31f887fbcb05da3d88e1b765
https://doi.org/10.21203/rs.3.rs-668663/v1
https://doi.org/10.21203/rs.3.rs-668663/v1