Direct tissue-sensing reprograms TLR4+ Tfh-like cells inflammatory profile in the joints of rheumatoid arthritis patients

Autor: Daniela Amaral-Silva, Rute Gonçalves, Rita C. Torrão, Rita Torres, Sandra Falcão, Maria João Gonçalves, Maria Paula Araújo, Maria José Martins, Carina Lopes, Agna Neto, José Marona, Tiago Costa, Walter Castelão, Ana Bento Silva, Inês Silva, Maria Helena Lourenço, Margarida Mateus, Nuno Pina Gonçalves, Santiago Manica, Manuela Costa, Fernando M. Pimentel-Santos, Ana Filipa Mourão, Jaime C. Branco, Helena Soares

Publikováno v: Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)

In order to identify how the synovial microenvironment impinges on CD4+ T cells pathogenic functions in Rheumatoid Arthritis (RA), Amaral-Silva examined RA patient blood and synovial fluif and identified the presence of a TLR4+ follicular helper T (T

Externí odkaz: https://doaj.org/article/d73f6ecb04594d11b6f47f71dd2151e3

The Role of Lung Ultrasound in Systemic Sclerosis

Autor: Miguel Gomes Guerra, Tânia Machado Pinto, Ana Águeda, Joana Rodrigues, José Marona, António Violante, Margarida Oliveira

Publikováno v: JCR: Journal of Clinical Rheumatology. 29:e32-e39

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e7f88521767c66aa3eab237f36b415f7
https://doi.org/10.1097/rhu.0000000000001947

Direct tissue-sensing reprograms TLR4+ Tfh-like cells inflammatory profile in the joints of rheumatoid arthritis patients

Autor: Maria Helena Lourenco, Daniela Amaral-Silva, Manuela Costa, Santiago Rodrigues Manica, Jaime Branco, Inês Peixoto Silva, Walter Castelão, M Mateus, Maria Paula Araujo, Rita Pinheiro Torres, Tiago R. D. Costa, Ana Filipa Mourão, José Marona, Ana Bento Silva, Sandra Falcão, Carina Lopes, Nuno Pina Gonçalves, Rita C. Torrao, Rute Gonçalves, Maria João Gonçalves, Helena Soares, Agna Neto, Maria Jose Martins, Fernando Pimentel-Santos

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)

Funding Information: We thank Cláudia Andrade for technical support and Juliana Gonçalves for testing samples for SARS-CoV-2 exposure. We are extremely grateful to all the participants of the study and to the whole rheumatology department at Hospit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d642545ff8d4d59f73dd5fa49cf17810

P8 Refractory thrombocytopenia in a patient with Systemic Lupus Erythematosus and secondary antiphospholipid syndrome

Autor: Jaime Branco, Manuela Costa, José Marona, Rita Torres, Nuno Gonçalves, Fernando Pimentel-Santos, Agna Neto, Santiago Rodrigues Manica, Maria João Gonçalves

Publikováno v: Poster presentations.

Background Thrombocytopenia is a frequent hematological manifestation in patients with systemic lupus erythematosus (SLE), usually treated with glucocorticoids, immunosuppressants (such as azathioprine and cyclophosphamide), intravenous immunoglobuli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::582aaa6affcb6822035b9b665f66559e
https://doi.org/10.1136/lupus-2020-eurolupus.57

Translation, cross-cultural adaptation and validation of the Osteoarthritis Quality of Life (OAQoL) questionnaire for use in Portugal

Autor: Manuela Costa, Jaime Branco, Ana Filipa Águeda, Carina Lopes, Alice Heaney, Stephen P. McKenna, Santiago Rodrigues-Manica, Sara Maia, Joao Lagoas Gomes, Fernando Pimentel-Santos, Anabela Barcelos, Tiago Costa, Cátia Duarte, José Marona

Publikováno v: Rheumatology International. 39:715-722

Osteoarthritis (OA) is the most prevalent rheumatic disease and is a leading cause of decreased quality of life (QoL). The OA Quality of Life questionnaire (OAQoL) is an OA-specific patient-reported outcome measures. The aim of this study was to tran

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36cdb4afc3b50d5b1761bd17ac862546
https://doi.org/10.1007/s00296-018-4197-8