Zobrazeno 1 - 10
of 16
pro vyhledávání: '"José Marıa Carazo"'
Autor:
Chris Morris, Paolo Andreetto, Lucia Banci, Alexandre M.J.J. Bonvin, Grzegorz Chojnowski, Laura del Cano, José Marıa Carazo, Pablo Conesa, Susan Daenke, George Damaskos, Andrea Giachetti, Natalie E.C. Haley, Maarten L. Hekkelman, Philipp Heuser, Robbie P. Joosten, Daniel Kouřil, Aleš Křenek, Tomáš Kulhánek, Victor S. Lamzin, Nurul Nadzirin, Anastassis Perrakis, Antonio Rosato, Fiona Sanderson, Joan Segura, Joerg Schaarschmidt, Egor Sobolev, Sergio Traldi, Mikael E. Trellet, Sameer Velankar, Marco Verlato, Martyn Winn
Publikováno v:
Journal of Structural Biology: X, Vol 1, Iss , Pp - (2019)
The West-Life project (https://about.west-life.eu/) is a Horizon 2020 project funded by the European Commission to provide data processing and data management services for the international community of structural biologists, and in particular to sup
Externí odkaz:
https://doaj.org/article/458ce0103a194fdd9e9d3dc10f76f835
Autor:
Pablo Conesa, Yunior C. Fonseca, Jorge Jiménez de la Morena, Grigory Sharov, Jose Miguel de la Rosa-Trevín, Ana Cuervo, Alberto García Mena, Borja Rodríguez de Francisco, Daniel del Hoyo, David Herreros, Daniel Marchan, David Strelak, Estrella Fernández-Giménez, Erney Ramírez-Aportela, Federico Pedro de Isidro-Gómez, Irene Sánchez, James Krieger, José Luis Vilas, Laura del Cano, Marcos Gragera, Mikel Iceta, Marta Martínez, Patricia Losana, Roberto Melero, Roberto Marabini, José María Carazo, Carlos Oscar Sánchez Sorzano
Publikováno v:
Biological Imaging, Vol 3 (2023)
Image-processing pipelines require the design of complex workflows combining many different steps that bring the raw acquired data to a final result with biological meaning. In the image-processing domain of cryo-electron microscopy single-particle a
Externí odkaz:
https://doaj.org/article/7e0c16ca201946a0af77da21601e8521
Autor:
David Herreros, Roy R. Lederman, James Krieger, Amaya Jiménez-Moreno, Marta Martínez, David Myška, David Strelak, Jiri Filipovic, Ivet Bahar, Jose Maria Carazo, Carlos Oscar S. Sanchez
Publikováno v:
IUCrJ, Vol 8, Iss 6, Pp 992-1005 (2021)
Structural biology has evolved greatly due to the advances introduced in fields like electron microscopy. This image-capturing technique, combined with improved algorithms and current data processing software, allows the recovery of different conform
Externí odkaz:
https://doaj.org/article/67b272f266e3477db975106481fc43d1
Publikováno v:
Micromachines, Vol 14, Iss 10, p 1835 (2023)
Cryogenic electron microscopy (Cryo-EM) has been established as one of the key players in structural biology. It can reconstruct a 3D model of a sample at a near-atomic resolution. With the increasing number of facilities, faster microscopes, and new
Externí odkaz:
https://doaj.org/article/1942109439cd4492a1ee496917d9825a
Autor:
Ruben Sanchez-Garcia, Josue Gomez-Blanco, Ana Cuervo, Jose Maria Carazo, Carlos Oscar S. Sorzano, Javier Vargas
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-8 (2021)
Sanchez-Garcia et al. present DeepEMhancer, a deep learning-based method that can automatically perform post-processing of raw cryo-electron microscopy density maps. The authors report that DeepEMhancer globally improves local quality of density maps
Externí odkaz:
https://doaj.org/article/d8dd5236e640466ead393144dcbe902e
Autor:
Fabio Lapenta, Jana Aupič, Marco Vezzoli, Žiga Strmšek, Stefano Da Vela, Dmitri I. Svergun, José María Carazo, Roberto Melero, Roman Jerala
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Coiled-coil protein origami is a strategy for the de novo design of polypeptide nanostructures based on coiled-coil dimer forming peptides, where a single chain protein folds into a polyhedral cage. Here, the authors design a single-chain triangular
Externí odkaz:
https://doaj.org/article/59b662ee2eb34c1b9ef2ffa7c77f0b87
Autor:
Erney Ramírez-Aportela, David Maluenda, Yunior C. Fonseca, Pablo Conesa, Roberto Marabini, J. Bernard Heymann, Jose Maria Carazo, Carlos Oscar S. Sorzano
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-7 (2021)
Here, the authors present a cryo-EM validation method for the local analysis of the map-to-model fit and introduce FSC-Q as a quality measure. FSC-Q provides a quantitative estimation of how much of the model is supported by the signal content of the
Externí odkaz:
https://doaj.org/article/b0f9ffcd38594ff8b4a765a4f399ce87
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-7 (2020)
It is important to analyse the local resolution of cryo-EM maps. Here the authors present MonoDir, a fully automatic and parameter free method for the directional local resolution analysis of cryo-EM maps that requires only the final map as input and
Externí odkaz:
https://doaj.org/article/d28160f74bc64145bdc9c8f9ed6bfb11
Autor:
Erney Ramírez-Aportela, Javier Mota, Pablo Conesa, Jose Maria Carazo, Carlos Oscar S. Sorzano
Publikováno v:
IUCrJ, Vol 6, Iss 6, Pp 1054-1063 (2019)
In this article, a method is presented to estimate a new local quality measure for 3D cryoEM maps that adopts the form of a `local resolution' type of information. The algorithm (DeepRes) is based on deep-learning 3D feature detection. DeepRes is ful
Externí odkaz:
https://doaj.org/article/4b7d7cc24286494f89c4d1f87cb1a709
Autor:
Ruben Sanchez-Garcia, Joan Segura, David Maluenda, Jose Maria Carazo, Carlos Oscar S. Sorzano
Publikováno v:
IUCrJ, Vol 5, Iss 6, Pp 854-865 (2018)
Single-particle cryo-electron microscopy (cryo-EM) has recently become a mainstream technique for the structural determination of macromolecules. Typical cryo-EM workflows collect hundreds of thousands of single-particle projections from thousands of
Externí odkaz:
https://doaj.org/article/4fb99a5c52234ad182c7d11f5bb0840a