Zobrazeno 1 - 10
of 846
pro vyhledávání: '"José María Gutiérrez"'
Autor:
Andrés Sánchez, Maykel Cerdas, Jairo Gutiérrez, Mariángela Vargas, Álvaro Segura, María Herrera, Stephanie Chaves-Araya, Ronald Sánchez, Mauren Villalta, Gina Durán, Adriana Sánchez, Gabriela Solano, Daniel Cordero, Paola Sánchez, José María Gutiérrez, Guillermo León
Publikováno v:
Toxicon: X, Vol 23, Iss , Pp 100202- (2024)
The performance of dynamic body-feed filtration (DBF) in the removal of bulky solids produced during the manufacturing of snake antivenoms using the caprylic acid method was evaluated. For this purpose, diatomites with different filterability propert
Externí odkaz:
https://doaj.org/article/9f1dac6573104a6ab46f5bb6eaaf9426
Autor:
Álvaro Segura, Edwin Moscoso, Deibid Umaña, Mariángela Vargas, Andrés Sánchez, Andrés Hernández, Gina Durán, Mauren Villalta, Aarón Gómez, María Herrera, Mauricio Arguedas, José María Gutiérrez, Guillermo León
Publikováno v:
Toxicon: X, Vol 24, Iss , Pp 100206- (2024)
Snakebite in the Middle East and North Africa (MENA) is a public health problem whose magnitude is not fully known. Several antivenoms are available in these regions, but these formulations are designed for restricted geographical settings. Many coun
Externí odkaz:
https://doaj.org/article/928fff00033e4a7f949e078d127950f1
Publikováno v:
Toxicon: X, Vol 22, Iss , Pp 100195- (2024)
Mice are routinely used in snake venom research but are costly and subject to pain and suffering. The crustacean Artemia salina could be an alternative to mice, but data to support its adoption in snake venom research is limited. The aim of the prese
Externí odkaz:
https://doaj.org/article/4bb3bf52eb5d4043b7a525db4443bb54
Autor:
Andrés Sánchez, Gina Durán, Álvaro Segura, María Herrera, Mariángela Vargas, Mauren Villalta, Mauricio Arguedas, Edwin Moscoso, Deibid Umaña, Aarón Gómez, José María Gutiérrez, Guillermo León
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 5 (2024)
Externí odkaz:
https://doaj.org/article/bbca7875c13f4c68b4b67aff11849bad
Autor:
Steven R. Hall, Sean A. Rasmussen, Edouard Crittenden, Charlotte A. Dawson, Keirah E. Bartlett, Adam P. Westhorpe, Laura-Oana Albulescu, Jeroen Kool, José María Gutiérrez, Nicholas R. Casewell
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Morbidity from snakebite envenoming affects approximately 400,000 people annually. Tissue damage at the bite-site often leaves victims with catastrophic life-long injuries and is largely untreatable by current antivenoms. Repurposed small mo
Externí odkaz:
https://doaj.org/article/e9078a0bbeb241e9a8145f4cb4841a67
Autor:
William Laprade, Keirah E. Bartlett, Charlotte R. Christensen, Taline D. Kazandjian, Rohit N. Patel, Edouard Crittenden, Charlotte A. Dawson, Marjan Mansourvar, Darian S. Wolff, Thomas Fryer, Andreas H. Laustsen, Nicholas R. Casewell, José María Gutiérrez, Steven R. Hall, Timothy P. Jenkins
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Snakebite envenoming is a global public health issue that causes significant morbidity and mortality, particularly in low-income regions of the world. The clinical manifestations of envenomings vary depending on the snake's venom, with paral
Externí odkaz:
https://doaj.org/article/6bbe56adfb85480a807ac5e7250494ff
Autor:
Juliette Borri, José María Gutiérrez, Cecilie Knudsen, Abdulrazaq G Habib, Maya Goldstein, Andrew Tuttle
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 3, p e0012052 (2024)
BackgroundProgress in snakebite envenoming (SBE) therapeutics has suffered from a critical lack of data on the research and development (R&D) landscape. A database characterising this information would be a powerful tool for coordinating and accelera
Externí odkaz:
https://doaj.org/article/c8f29305cc75489488c63787f64f87cd
Autor:
Aarón Gómez, Andrés Sánchez, Gina Durán, Mauren Villalta, Álvaro Segura, Mariángela Vargas, María Herrera, Melvin Sánchez, José María Gutiérrez, Guillermo León
Publikováno v:
Toxicon: X, Vol 21, Iss , Pp 100183- (2024)
Snakebite envenomation is a neglected tropical disease posing a high toll of mortality and morbidity in sub-Saharan Africa. Polyspecific antivenoms of broad effectiveness and specially designed for this region require a detailed understanding of the
Externí odkaz:
https://doaj.org/article/0c29e73ada0849328c40429d68d8deb4
Autor:
Gabriela Solano, Stuart Ainsworth, Adriana Sánchez, Mauren Villalta, Paola Sánchez, Gina Durán, José María Gutiérrez, Guillermo León
Publikováno v:
Toxicon: X, Vol 21, Iss , Pp 100187- (2024)
As injectable therapeutics, snake antivenoms must meet specifications for endotoxin content. The Limulus amebocyte lysate (LAL) test was used to evaluate the endotoxin content in several commercially available antivenoms released for clinical use. It
Externí odkaz:
https://doaj.org/article/cce0b6f96a6b4a528fa208ecb94d3780
Autor:
Francisco C. P. Coimbra, Elda E. Sanchez, Bruno Lomonte, José María Gutiérrez, Juan J. Calvete, Bryan G. Fry
Publikováno v:
Toxins, Vol 16, Iss 7, p 291 (2024)
This study investigated the intraspecific and interspecific variability in the venom effects of Agkistrodon viperid snake species and subspecies (eleven venoms total) on plasma clotting times, fibrinogen levels, and fibrin clot strength. Significant
Externí odkaz:
https://doaj.org/article/d11216eff6d3468cac8f3afc91554759