Zobrazeno 1 - 10
of 20
pro vyhledávání: '"José Manuel Monroy Kuhn"'
Autor:
Paul Petrus, Marlene Cervantes, Muntaha Samad, Tomoki Sato, Alina Chao, Shogo Sato, Kevin B. Koronowski, Grace Park, Yasmine Alam, Niklas Mejhert, Marcus M. Seldin, José Manuel Monroy Kuhn, Kenneth A. Dyar, Dominik Lutter, Pierre Baldi, Peter Kaiser, Cholsoon Jang, Paolo Sassone-Corsi
Publikováno v:
Molecular Metabolism, Vol 64, Iss , Pp 101556- (2022)
Objective: The circadian clock aligns physiology with the 24-hour rotation of Earth. Light and food are the main environmental cues (zeitgebers) regulating circadian rhythms in mammals. Yet, little is known about the interaction between specific diet
Externí odkaz:
https://doaj.org/article/6340d9330cd0493c9aabbf8e8c886c21
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-17 (2021)
Abstract Background Most insects are relatively short-lived, with a maximum lifespan of a few weeks, like the aging model organism, the fruit-fly Drosophila melanogaster. By contrast, the queens of many social insects (termites, ants and some bees) c
Externí odkaz:
https://doaj.org/article/5503772503694c41ab6cf9dce660129d
Autor:
Goetz Hartleben, Kenji Schorpp, Yun Kwon, Barbara Betz, Foivos‐Filippos Tsokanos, Zahra Dantes, Arlett Schäfer, Ina Rothenaigner, José Manuel Monroy Kuhn, Pauline Morigny, Lisa Mehr, Sean Lin, Susanne Seitz, Janina Tokarz, Anna Artati, Jerzy Adamsky, Oliver Plettenburg, Dominik Lutter, Martin Irmler, Johannes Beckers, Maximilian Reichert, Kamyar Hadian, Anja Zeigerer, Stephan Herzig, Mauricio Berriel Diaz
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 4, Pp 1-21 (2021)
Abstract By accentuating drug efficacy and impeding resistance mechanisms, combinatorial, multi‐agent therapies have emerged as key approaches in the treatment of complex diseases, most notably cancer. Using high‐throughput drug screens, we uncov
Externí odkaz:
https://doaj.org/article/5b69fc35368c4378aea983eb723c06a2
Autor:
Valentina S. Klaus, Sonja C. Schriever, José Manuel Monroy Kuhn, Andreas Peter, Martin Irmler, Janina Tokarz, Cornelia Prehn, Gabi Kastenmüller, Johannes Beckers, Jerzy Adamski, Alfred Königsrainer, Timo D. Müller, Martin Heni, Matthias H. Tschöp, Paul T. Pfluger, Dominik Lutter
Publikováno v:
Molecular Metabolism, Vol 53, Iss , Pp 101295- (2021)
Objective: Technological advances have brought a steady increase in the availability of various types of omics data, from genomics to metabolomics. Integrating these multi-omics data is a chance and challenge for systems biology; yet, tools to fully
Externí odkaz:
https://doaj.org/article/d17775f6456844a1ba26907fd0446001
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0210371 (2019)
Social insects provide promising new avenues for aging research. Within a colony, individuals that share the same genetic background can differ in lifespan by up to two orders of magnitude. Reproducing queens (and in termites also kings) can live for
Externí odkaz:
https://doaj.org/article/a3fd0cc788144f4b80c710f1ba7e8b4f
Publikováno v:
Bioinformatics Advances. 2
Summary Today’s immense growth in complex biological data demands effective and flexible tools for integration, analysis and extraction of valuable insights. Here, we present CoNI, a practical R package for the unsupervised integration of numerical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d24baa11b5ae744a13c181d5649bfd7e
https://doi.org/10.1093/bioadv/vbac042
https://doi.org/10.1093/bioadv/vbac042
Autor:
Johannes Beckers, Oliver Plettenburg, Sean Lin, Foivos-Filippos Tsokanos, Anna Artati, Susanne Seitz, Arlett Schäfer, Goetz Hartleben, Martin Irmler, Yun Kwon, Lisa Mehr, Mauricio Berriel Diaz, Kenji Schorpp, Anja Zeigerer, Barbara Betz, Zahra Dantes, Jerzy Adamsky, Pauline Morigny, José Manuel Monroy Kuhn, Stephan Herzig, Janina Tokarz, Kamyar Hadian, Ina Rothenaigner, Dominik Lutter, Maximilian Reichert
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 4, Pp n/a-n/a (2021)
EMBO Molecular Medicine 13 (2021), Nr. 4
EMBO Molecular Medicine
EMBO Mol. Med.:e12461 (2021)
EMBO Molecular Medicine 13 (2021), Nr. 4
EMBO Molecular Medicine
EMBO Mol. Med.:e12461 (2021)
By accentuating drug efficacy and impeding resistance mechanisms, combinatorial, multi‐agent therapies have emerged as key approaches in the treatment of complex diseases, most notably cancer. Using high‐throughput drug screens, we uncovered dist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::844403979915d09946eb8173a03d57e3
https://doaj.org/article/5b69fc35368c4378aea983eb723c06a2
https://doaj.org/article/5b69fc35368c4378aea983eb723c06a2
Autor:
Barbara Feldmeyer, Thomas Flatt, Denise Aumer, Megha Majoe, Abel Bernadou, Marah Stoldt, Robert J. Paxton, Matteo Antoine Negroni, Karen Meusemann, José Manuel Monroy Kuhn, Alice Séguret, Volker Nehring, Judith Korb, Silu Lin, Jürgen Heinze, Daniel Elsner, Romain Libbrecht, Susanne Foitzik
Publikováno v:
Philosophical Transactions of the Royal Society B: Biological Sciences
The exceptional longevity of social insect queens despite their lifelong high fecundity remains poorly understood in ageing biology. To gain insights into the mechanisms that might underlie ageing in social insects, we compared gene expression patter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e2d046f6c7141a35a35cb67db271e03
https://pubmed.ncbi.nlm.nih.gov/33678016
https://pubmed.ncbi.nlm.nih.gov/33678016
Autor:
Patrick-Simon Welz, Roberta Carriero, Paolo Kunderfranco, Selma Masri, Siwei Chen, Arun Kumar, Pierre Baldi, Thomas Mortimer, Kenneth A. Dyar, Kevin B. Koronowski, Jacob G. Smith, Jiejun Shi, Oleg Deryagian, Salvador Aznar Benitah, Wei Li, Kohei Shimaji, José Manuel Monroy Kuhn, Paul Petrus, Muntaha Samad, Valentina M. Zinna, Carolina Magdalen Greco, Sung Kook Chun, Mireia Vaca-Dempere, Cassandra Van, Pura Muñoz-Cánoves, Paolo Sassone-Corsi, Marcus M. Seldin, Tomoki Sato, Dominik Lutter
Publikováno v:
Science Advances
Science advances, vol 7, iss 39
Sci. Adv. 7:eabi7828 (2021)
Science advances, vol 7, iss 39
Sci. Adv. 7:eabi7828 (2021)
Description
The inner workings of the clock system rely on communicating signals between distal tissues to maintain daily metabolism.
The mammalian circadian clock, expressed throughout the brain and body, controls daily metabolic homeostas
The inner workings of the clock system rely on communicating signals between distal tissues to maintain daily metabolism.
The mammalian circadian clock, expressed throughout the brain and body, controls daily metabolic homeostas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cfee1665b6f51022f3d9d13b3b9a63f
Autor:
Johannes Beckers, Gabi Kastenmüller, Sonja C. Schriever, Timo D. Müller, Jerzy Adamski, Valentina Klaus, Matthias H. Tschöp, Martin Irmler, José Manuel Monroy Kuhn, Janina Tokarz, Paul T. Pfluger, Andreas Peter, Dominik Lutter, Cornelia Prehn, Martin Heni, Alfred Königsrainer
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 53, Iss, Pp 101295-(2021)
Molecular Metabolism, Vol 53, Iss, Pp 101295-(2021)
Objective Technological advances have brought a steady increase in the availability of various types of omics data, from genomics to metabolomics. Integrating these multi-omics data is a chance and challenge for systems biology; yet, tools to fully t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::529bc556d07b037bba40986d651c5041
https://doi.org/10.1016/j.molmet.2021.101295
https://doi.org/10.1016/j.molmet.2021.101295