Zobrazeno 1 - 10
of 107
pro vyhledávání: '"José Manuel López-Nicolás"'
Autor:
Silvia Navarro-Orcajada, Francisco José Vidal-Sánchez, Irene Conesa, Francisco Escribano-Naharro, Adrián Matencio, José Manuel López-Nicolás
Publikováno v:
Biomedicines, Vol 11, Iss 11, p 3023 (2023)
Isorhapontigenin has been proposed as a better alternative for oral administration than the famous resveratrol, as it shares many biological activities, but with a structure that could make its delivery easier. Although this hydrophobic structure cou
Externí odkaz:
https://doaj.org/article/7004523590344946b275a774be726e71
Autor:
Silvia Navarro-Orcajada, Francisco José Vidal-Sánchez, Irene Conesa, Adrián Matencio, José Manuel López-Nicolás
Publikováno v:
Biomolecules, Vol 13, Iss 8, p 1270 (2023)
It has been argued that methoxylated stilbenes are better candidates for oral administration than hydroxylated stilbenes, including resveratrol, as they share many biological activities but have better bioavailability. By contrast, they have a disadv
Externí odkaz:
https://doaj.org/article/89fbd28538ca405cb9e6326f3b2f8068
Autor:
Sergio Chevilly, Laura Dolz-Edo, Luna Morcillo, Alberto Vilagrosa, José Manuel López-Nicolás, Lynne Yenush, José M. Mulet
Publikováno v:
BMC Plant Biology, Vol 21, Iss 1, Pp 1-16 (2021)
Abstract Background Salt stress is one of the main constraints determining crop productivity, and therefore one of the main limitations for food production. The aim of this study was to characterize the salt stress response at the physiological and m
Externí odkaz:
https://doaj.org/article/bf22524cc937412286dbec669c5c5f3f
Autor:
Silvia Navarro-Orcajada, Adrián Matencio, Cristina Vicente-Herrero, Francisco García-Carmona, José Manuel López-Nicolás
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Neochlorogenic acid, a less-studied isomer of chlorogenic acid, has been seen to posses antioxidant, antifungal, anti-inflammatory and anticarcinogenic effects, which makes it an interesting candidate for incorporation in functional foods. H
Externí odkaz:
https://doaj.org/article/8d4cbdbccf74461bb7d6b418b845ae7f
Autor:
Adrián Matencio, Alberto Rubin Pedrazzo, Alessandro Difalco, Silvia Navarro-Orcajada, Yousef Khazeai Monfared, Irene Conesa, Azam Rezayat, José Manuel López-Nicolás, Francesco Trotta
Publikováno v:
Polymers, Vol 13, Iss 23, p 4226 (2021)
Cyclodextrins (CDs) are a good alternative to reduce or enhance different biomolecule characteristics and have demonstrated great results in food science. However, CDs present intrinsic limitations that can be solved by derivative synthesis. This rev
Externí odkaz:
https://doaj.org/article/82b5f7ae71904927ae8fd6e5576ed23e
Autor:
Silvia Lucia Appleton, Silvia Navarro-Orcajada, Francisco Juan Martínez-Navarro, Fabrizio Caldera, José Manuel López-Nicolás, Francesco Trotta, Adrián Matencio
Publikováno v:
Biomolecules, Vol 11, Iss 9, p 1384 (2021)
Inflammation is a biological response of the immune system to harmful stimuli. Importantly, inflammation is also a hallmark of several human diseases such as cancer or diabetes. Novel drugs to treat this response are constantly researched, but the fo
Externí odkaz:
https://doaj.org/article/7783e7d5b48c47349ca12cc6357bc406
Autor:
Adrián Matencio, Fabrizio Caldera, Claudio Cecone, José Manuel López-Nicolás, Francesco Trotta
Publikováno v:
Pharmaceuticals, Vol 13, Iss 10, p 281 (2020)
There have been many reviews of the cyclic oligosaccharide cyclodextrin (CD) and CD-based materials used for drug delivery, but the capacity of CDs to complex different agents and their own intrinsic properties suggest they might also be considered f
Externí odkaz:
https://doaj.org/article/68a7bf42595b4452b0ef1dee4825229a
Publikováno v:
Pharmaceuticals, Vol 13, Iss 9, p 225 (2020)
Our desire to live longer has led to an ever-increasing number of novel antiaging products. However, few molecules have any real effect and new ones need to be studied before they can be used commercially. In this contribution, activation of the calo
Externí odkaz:
https://doaj.org/article/e10410458898468d9e983704f929572b
Autor:
Nilesh Kumar Dhakar, Adrián Matencio, Fabrizio Caldera, Monica Argenziano, Roberta Cavalli, Chiara Dianzani, Marco Zanetti, José Manuel López-Nicolás, Francesco Trotta
Publikováno v:
Pharmaceutics, Vol 11, Iss 10, p 545 (2019)
Resveratrol and oxyresveratrol are natural polyphenolic stilbenes with several important pharmacological activities. However, low solubility and aqueous instability are the major limitations in their drug delivery applications. In the present work, w
Externí odkaz:
https://doaj.org/article/14162655214141b68f9e3a22430262d5
Autor:
Adrián Matencio, Samanta Hernández-García, Francisco García-Carmona, José Manuel López-Nicolás
Publikováno v:
Polymers, Vol 11, Iss 5, p 801 (2019)
Roflumilast is an orally available inhibitor of phosphodiesterase (PDE) type 4, which is widely used in chronic obstructive pulmonary diseases. However, it has low solubility and adverse effects include diarrhea and nausea. Since its solubilization m
Externí odkaz:
https://doaj.org/article/bf77926bbefc4adaa13b53eb094dc9cc