Zobrazeno 1 - 10
of 41
pro vyhledávání: '"José Manuel Fernandez-Real"'
Autor:
Óscar Osorio-Conles, María Guitart, José María Moreno-Navarrete, Xavier Escoté, Xavier Duran, José Manuel Fernandez-Real, Anna María Gómez-Foix, Sonia Fernández-Veledo, Joan Vendrell
Publikováno v:
Molecular Medicine, Vol 23, Iss 1, Pp 225-234 (2017)
Abstract Coiled-coil domain-containing 80 (CCDC80) is an adipocyte-secreted protein that modulates glucose homeostasis in response to diet-induced obesity in mice. The objective of this study was to analyze the link between human CCDC80 and obesity.
Externí odkaz:
https://doaj.org/article/385806e7bbf844f3b629d539ff65dbbe
Publikováno v:
Nutrition & Diabetes, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract Background Mice experiments have underscored the efficacy of pharmacological inhibition of advanced glycation endproducts (AGEs) through the use of soluble receptors for advanced glycation endproducts (sRAGE) in mitigating obesity-linked met
Externí odkaz:
https://doaj.org/article/4ac19047d6ea42eaa66ac7451a8cb75e
Autor:
Milton-Fabian Suárez-Ortegón, Stela McLachlan, José-Manuel Fernandez-Real, Tomi-Pekka Tuomainen, Alex Aregbesola, Sarah H. Wild
Publikováno v:
Suárez-Ortegón, M F, McLachlan, S, Fernández-Real, J M, Tuomainen, T-P, Aregbesola, A & Wild, S H 2022, ' Serum ferritin and incident cardiometabolic diseases in Scottish adults ', Cardiovascular diabetology, vol. 21, no. 1, 26 . https://doi.org/10.1186/s12933-022-01450-7
Background Iron stores, estimated as ferritin levels, and type 2 diabetes (T2D) have been associated previously, while findings regarding coronary heart disease (CHD) and cerebrovascular disease (CEVD) are still inconclusive. No study has focused on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::074d6f4facb982bafe658223c76094f4
https://doi.org/10.1186/s12933-022-01450-7
https://doi.org/10.1186/s12933-022-01450-7
Autor:
Marisel Rosell-Díaz, Elena Santos-González, Anna Motger-Albertí, Laura Gallardo-Nuell, María Arnoriaga-Rodríguez, Clàudia Coll-Martínez, Lluís Ramió-Torrentà, Josep Garre-Olmo, Josep Puig, Rafael Ramos, Jordi Mayneris-Perxachs, José Manuel Fernández-Real
Publikováno v:
The Journal of Nutrition, Health and Aging, Vol 28, Iss 4, Pp 100190- (2024)
Objectives: Iron is important for neurogenesis, synaptic development, and neurotransmitter synthesis. Serum ferritin (SF) is a reliable marker for assessing iron stores. Therefore, we evaluated the cognitive function associated with SF levels. We als
Externí odkaz:
https://doaj.org/article/1e0edfd2417e4281ba344b858cc69185
Autor:
Marc Schoeler, Sandrine Ellero-Simatos, Till Birkner, Jordi Mayneris-Perxachs, Lisa Olsson, Harald Brolin, Ulrike Loeber, Jamie D. Kraft, Arnaud Polizzi, Marian Martí-Navas, Josep Puig, Antonio Moschetta, Alexandra Montagner, Pierre Gourdy, Christophe Heymes, Hervé Guillou, Valentina Tremaroli, José Manuel Fernández-Real, Sofia K. Forslund, Remy Burcelin, Robert Caesar
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Dietary lipids can affect metabolic health through gut microbiota-mediated mechanisms, but the influence of lipid-microbiota interaction on liver steatosis is largely unknown. We investigate the impact of dietary lipids on human gut microbio
Externí odkaz:
https://doaj.org/article/b3b8887947dd4c14b3e0120418bffa47
Autor:
Marisel Rosell-Díaz, Elena Santos-González, Anna Motger-Albertí, Lluís Ramió-Torrentà, Josep Garre-Olmo, Vicente Pérez-Brocal, Andrés Moya, Mariona Jové, Reinald Pamplona, Josep Puig, Rafael Ramos, José Manuel Fernández-Real, Jordi Mayneris-Perxachs
Publikováno v:
Gut Microbes, Vol 15, Iss 2 (2023)
ABSTRACTIron is required for the replication and growth of almost all bacterial species and in the production of myelin and neurotransmitters. Increasing clinical studies evidence that the gut microbiota plays a critical role in iron metabolism and c
Externí odkaz:
https://doaj.org/article/d1ebd50a50a540c0a793e69f8e4d4313
Autor:
Abdulbasit Amin, Marina Badenes, Johanna Tüshaus, Érika de Carvalho, Emma Burbridge, Pedro Faísca, Květa Trávníčková, André Barros, Stefania Carobbio, Pedro M. Domingos, Antonio Vidal-Puig, Luís F. Moita, Sarah Maguire, Kvido Stříšovský, Francisco J. Ortega, José Manuel Fernández-Real, Stefan F. Lichtenthaler, Colin Adrain
Publikováno v:
Molecular Metabolism, Vol 73, Iss , Pp 101731- (2023)
Objective: The metalloprotease ADAM17 (also called TACE) plays fundamental roles in homeostasis by shedding key signaling molecules from the cell surface. Although its importance for the immune system and epithelial tissues is well-documented, little
Externí odkaz:
https://doaj.org/article/05555155e4744951844c5a7be30e9720
Autor:
Jessica Latorre, Ramon Díaz-Trelles, Ferran Comas, Aleix Gavaldà-Navarro, Edward Milbank, Nathalia Dragano, Samantha Morón-Ros, Rajesh Mukthavaram, Francisco Ortega, Anna Castells-Nobau, Núria Oliveras-Cañellas, Wifredo Ricart, Priya P. Karmali, Kiyoshi Tachikawa, Pad Chivukula, Francesc Villarroya, Miguel López, Marta Giralt, José Manuel Fernández-Real, José María Moreno-Navarrete
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 29, Iss , Pp 599-613 (2022)
Circulating lipopolysaccharide-binding protein (LBP) is increased in individuals with liver steatosis. We aimed to evaluate the possible impact of liver LBP downregulation using lipid nanoparticle-containing chemically modified LBP small interfering
Externí odkaz:
https://doaj.org/article/2318b693c0cb490ab904a421bf554622
Autor:
Isabel Huber-Ruano, Enrique Calvo, Jordi Mayneris-Perxachs, M-Mar Rodríguez-Peña, Victòria Ceperuelo-Mallafré, Lídia Cedó, Catalina Núñez-Roa, Joan Miro-Blanch, María Arnoriaga-Rodríguez, Aurélie Balvay, Claire Maudet, Pablo García-Roves, Oscar Yanes, Sylvie Rabot, Ghjuvan Micaelu Grimaud, Annachiara De Prisco, Angela Amoruso, José Manuel Fernández-Real, Joan Vendrell, Sonia Fernández-Veledo
Publikováno v:
Microbiome, Vol 10, Iss 1, Pp 1-22 (2022)
Abstract Background Succinate is produced by both human cells and by gut bacteria and couples metabolism to inflammation as an extracellular signaling transducer. Circulating succinate is elevated in patients with obesity and type 2 diabetes and is l
Externí odkaz:
https://doaj.org/article/a570aa898a594f34ad77716587a8d6a4
Autor:
Jessica Latorre, Francisco Ortega, Núria Oliveras-Cañellas, Ferran Comas, Aina Lluch, Aleix Gavaldà-Navarro, Samantha Morón-Ros, Wifredo Ricart, Francesc Villarroya, Marta Giralt, José Manuel Fernández-Real, José María Moreno-Navarrete
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 27, Iss , Pp 870-879 (2022)
Lipopolysaccharide binding protein (Lbp) has been recently identified as a relevant component of innate immunity response associated to adiposity. Here, we aimed to investigate the impact of adipose tissue Lbp on weight gain and white adipose tissue
Externí odkaz:
https://doaj.org/article/f9dbfee1ff5c4a26b586d69304553e65