Zobrazeno 1 - 10
of 33
pro vyhledávání: '"José Manuel Aldrey"'
Autor:
Anxo Manuel Minguillón Pereiro, Beatriz Quintáns Castro, Alberto Ouro Villasante, José Manuel Aldrey Vázquez, Julia Cortés Hernández, Marta Aramburu-Núñez, Manuel Arias Gómez, Isabel Jiménez Martín, Tomás Sobrino, Juan Manuel Pías-Peleteiro
Publikováno v:
Biomedicines, Vol 12, Iss 8, p 1881 (2024)
Background: Monogenic Alzheimer’s disease (AD) has severe health and socioeconomic repercussions. Its rarest cause is presenilin 2 (PSEN2) gene mutations. We present two new cases with presumed PSEN2-AD with unusual clinical and neuroimaging findin
Externí odkaz:
https://doaj.org/article/76985eca25c14df980206ab1554793b7
Autor:
Antía Custodia, Marta Aramburu-Núñez, Noemí Gómez-Lado, Diego Álvarez-Rafael, Mariña Rodríguez-Arrizabalaga, Mónica Castro, Juan Manuel Pías-Peleteiro, Javier Camino-Castiñeiras, José Manuel Aldrey, Daniel Romaus-Sanjurjo, Pablo Aguiar, Alberto Ouro, Tomás Sobrino
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S389- (2023)
Externí odkaz:
https://doaj.org/article/dda6b59b0cdc40f6a46b56f7da18c05a
Autor:
Antía Custodia, Marta Aramburu-Núñez, Mariña Rodríguez-Arrizabalaga, Juan Manuel Pías-Peleteiro, Laura Vázquez-Vázquez, Javier Camino-Castiñeiras, José Manuel Aldrey, José Castillo, Alberto Ouro, Tomás Sobrino, Daniel Romaus-Sanjurjo
Publikováno v:
Cells, Vol 12, Iss 6, p 962 (2023)
Alzheimer’s disease (AD) is the most common degenerative disorder in the elderly in developed countries. Currently, growing evidence is pointing at endothelial dysfunction as a key player in the cognitive decline course of AD. As a main component o
Externí odkaz:
https://doaj.org/article/fbeb72730f184b6b81536d805c6075db
Autor:
Miguel Ángel Rivas-Fernández, Mónica Lindín, Montserrat Zurrón, Fernando Díaz, José Manuel Aldrey-Vázquez, Juan Manuel Pías-Peleteiro, Laura Vázquez-Vázquez, Arturo Xosé Pereiro, Cristina Lojo-Seoane, Ana Nieto-Vieites, Santiago Galdo-Álvarez
Publikováno v:
Frontiers in Human Neuroscience, Vol 16 (2022)
IntroductionThis study aimed to evaluate, in adults with mild cognitive impairment (MCI), the brain atrophy that may distinguish between three AT(N) biomarker-based profiles, and to determine its clinical value.MethodsStructural MRI (sMRI) was employ
Externí odkaz:
https://doaj.org/article/e34bc6765a1d469e8f36bd2f71ca9693
Autor:
Antía Custodia, Daniel Romaus-Sanjurjo, Marta Aramburu-Núñez, Diego Álvarez-Rafael, Laura Vázquez-Vázquez, Javier Camino-Castiñeiras, Yago Leira, Juan Manuel Pías-Peleteiro, José Manuel Aldrey, Tomás Sobrino, Alberto Ouro
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8082 (2022)
Alzheimer’s disease (AD) is considered the most prevalent neurodegenerative disease and the leading cause of dementia worldwide. Sphingolipids, such as ceramide or sphingosine 1-phosphate, are bioactive molecules implicated in structural and signal
Externí odkaz:
https://doaj.org/article/7023f8594acf4d39aa8695df9464efa5
Autor:
Daniel Romaus-Sanjurjo, Antía Custodia, Marta Aramburu-Núñez, Adrián Posado-Fernández, Laura Vázquez-Vázquez, Javier Camino-Castiñeiras, Yago Leira, Juan Manuel Pías-Peleteiro, José Manuel Aldrey, Alberto Ouro, Tomás Sobrino
Publikováno v:
Symmetry, Vol 13, Iss 12, p 2333 (2021)
In 1959, E. G. Gray described two different types of synapses in the brain for the first time: symmetric and asymmetric. Later on, symmetric synapses were associated with inhibitory terminals, and asymmetric synapses to excitatory signaling. The bala
Externí odkaz:
https://doaj.org/article/6c422d50a45d4ded863a973f38700c11
Autor:
João Botelho, Yago Leira, João Viana, Vanessa Machado, Patrícia Lyra, José Manuel Aldrey, Juan Manuel Pías-Peleteiro, Juan Blanco, Tomás Sobrino, José João Mendes
Publikováno v:
Nutrients, Vol 13, Iss 3, p 924 (2021)
Patients suffering from periodontitis are at a higher risk of developing cognitive dysfunction. However, the mediation effect of an inflammatory diet and serum vitamin D levels in this link is unclear. In total, 2062 participants aged 60 years or old
Externí odkaz:
https://doaj.org/article/68f8343c51844ffc8794fcfad7a62abf
Akademický článek
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Autor:
Pablo Aguiar, Julia Cortés, Álvaro Ruibal, Noemí Gómez-Lado, José Manuel Aldrey, Alzheimer’s Disease Neuroimaging Initiative, Anxo Fernández-Ferreiro, Alexis Moscoso, Jesús Silva-Rodríguez
Publikováno v:
Neurobiology of Aging. 84:1-8
It is unclear whether episodic memory is an appropriate descriptor of the cognitive continuum in mild cognitive impairment (MCI). Here, we investigated the ability of episodic memory to track cognitive changes in patients with MCI with biomarker evid
Autor:
Miguel Ángel Rivas-Fernández, Mónica Lindín, Montserrat Zurrón, Fernando Díaz, José Manuel Aldrey-Vázquez, Juan Manuel Pías-Peleteiro, Laura Vázquez-Vázquez, Arturo Xosé Pereiro, Cristina Lojo-Seoane, Ana Nieto-Vieites, Santiago Galdo-Álvarez
Publikováno v:
Frontiers in human neuroscience. 16
Introduction: This study aimed to evaluate, in adults with mild cognitive impairment (MCI), the brain atrophy that may distinguish between three AT(N) biomarker-based profiles, and to determine its clinical value. Methods: Structural MRI (sMRI) was e