Zobrazeno 1 - 8
of 8
pro vyhledávání: '"José M.V. Hernández-Vázquez"'
Autor:
Luis Sánchez Sánchez, María L. Escobar-Sánchez, Jazmin Ciciolil Hilario-Martínez, Jesús Sandoval-Ramírez, Benny Weiss-Steider, José M.V. Hernández-Vázquez, María A. Fernández-Herrera, Hugo López-Muñoz, Fernando Flores-Guzmán
Publikováno v:
European Journal of Pharmacology. 871:172942
(25R)-spirost-5-en-3β-ol, also known as diosgenin (DSG), exerts antiproliferative activity on diverse cell lines, induces apoptosis, and acts as a chemopreventative agent. However, the relationship between DSG glycosides and apoptotic, necrotic, and
Autor:
Edgar Zenteno, María L. Escobar, Hugo López-Muñoz, Jesús Sandoval-Ramírez, José M.V. Hernández-Vázquez, C. Hilario-Martínez, Luis Sánchez-Sánchez, María A. Fernández-Herrera
Publikováno v:
Apoptosis. 20:1623-1635
The antiproliferative and cytotoxic activity of glucolaxogenin and its ability to induce apoptosis and autophagy in cervical cancer cells are reported. We ascertained that glucolaxogenin exerts an inhibitory effect on the proliferation of HeLa, CaSki
Autor:
Hugo López-Muñoz, Edgar Zenteno, Rebeca López-Marure, Ricardo Lascurain-Ledesma, Luis Sánchez-Sánchez, Ma. Luisa Escobar-Sánchez, José M.V. Hernández-Vázquez, Benny Weiss-Steider
Publikováno v:
Archives of Gynecology and Obstetrics. 287:755-763
Tumor cells are known to secrete cytokines that modify their microenvironment in order to favor their survival and continuous proliferation. In this work, we evaluated if TGF-β secreted in vitro by cervical cancer cells could interfere with the prol
Autor:
Jesús J. Alvarado-Sansininea, Patricia Demare, José M.V. Hernández-Vázquez, Ignacio Regla, Benny Weiss-Steider, Iván Monsalvo-Montiel, Hugo López-Muñoz, María L. Escobar, Luis Sánchez-Sánchez
Publikováno v:
European journal of pharmacology. 758
Capsaicin is a potent inducer of apoptosis in tumourreceptor potential vanilloid 1 (TRPV1). The present study determined the IC50 and cytotoxic and apoptotic activities of the Capsaicin analogues Rinvanil and Phenylacetylrinvanil (PhAR) on three cerv
Autor:
B. Mario Pinto, María A. Fernández-Herrera, Hugo López-Muñoz, María L. Escobar-Sánchez, Jesús Sandoval-Ramírez, José M.V. Hernández-Vázquez, Luis Sánchez-Sánchez
Publikováno v:
European journal of medicinal chemistry. 54
The synthesis of glucosamine derivatives of the steroidal sapogenins diosgenin and hecogenin using the N-phthaloyl protected trichloroacetimidate of d-glucosamine as donor and TMSOTf as promoter is reported. The corresponding glycoconjugates were tra
Autor:
B. Mario Pinto, Moisés López-Dávila, María A. Fernández-Herrera, Hugo López-Muñoz, Sankar Mohan, José M.V. Hernández-Vázquez, Jesús Sandoval-Ramírez, María L. Escobar-Sánchez, Luis Sánchez-Sánchez
Publikováno v:
European journal of medicinal chemistry. 46(9)
The synthesis and biological evaluation of the new cholestane glycoside (25R)-3β,16β-diacetoxy-22-oxocholest-5-en-26-yl β-d-glucopyranoside starting from diosgenin is described. This compound showed selective antiproliferative activity against CaS
Autor:
María A. Fernández-Herrera, José M.V. Hernández-Vázquez, María L. Escobar-Sánchez, Hugo López-Muñoz, B. Mario Pinto, Esmeralda Pérez-Cervantes, Sankar Mohan, Luis Sánchez-Sánchez, Ignacio Regla, Jesús Sandoval-Ramírez
Publikováno v:
European journal of medicinal chemistry. 45(11)
The synthesis of the new glycoside (25R)-3β,16β-diacetoxy-12,22-dioxo-5α-cholestan-26-yl β-D-glucopyranoside starting from hecogenin is described. This compound showed anti-cancer activity against cervicouterine cancer cells HeLa, CaSki and ViBo
Autor:
María L. Escobar-Sánchez, Hugo López-Muñoz, Jesús Sandoval-Ramírez, Moisés López-Dávila, José M.V. Hernández-Vázquez, Luis Sánchez-Sánchez, B. Mario Pinto, María A. Fernández-Herrera
Publikováno v:
Bioorganicmedicinal chemistry. 18(7)
Certain steroidal compounds have demonstrated an antiproliferative effect against several tumor cell lines; however, their complete role on cancer cells is not currently established. Herein, we report the synthesis and evaluation of two new 26-hydrox