Zobrazeno 1 - 10
of 33
pro vyhledávání: '"José M. Valdivielso"'
Autor:
Luz M. González, Nicolás R. Robles, Sonia Mota-Zamorano, José M. Valdivielso, Laura González-Rodríguez, Juan López-Gómez, Guillermo Gervasini
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Nephrosclerosis patients are at an exceptionally high cardiovascular (CV) risk. We aimed to determine whether genetic variability represented by 38 tag-SNPs in genes of the cyclooxygenase pathway (PTGS1, PTGS2, PTGES, PTGES2 and PTGES3) lead
Externí odkaz:
https://doaj.org/article/e2f9ee43073e4063a72b693a1ad151de
Autor:
Sonia Mota-Zamorano, Luz M. González, Nicolás R. Robles, José M. Valdivielso, José C. Arévalo-Lorido, Juan López-Gómez, Guillermo Gervasini
Publikováno v:
Annals of Medicine, Vol 54, Iss 1, Pp 3039-3051 (2022)
Background Diabetic nephropathy (DN) has become the major cause of end-stage kidney disease and is associated to an extremely high cardiovascular (CV) risk.Methods We screened 318 DN patients for 23 SNPs in four glucose transporters (SLC2A1, SLC2A2,
Externí odkaz:
https://doaj.org/article/fc02b76432544e2ba0cf5139d46a9c47
Autor:
Lidia Martínez Fernández, J. Emilio Sánchez-Alvarez, César Morís de la Tassa, José Joaquín Bande Fernández, Virtudes María, Elvira Fernández, José M. Valdivielso, Angels Betriu
Publikováno v:
Nefrología, Vol 41, Iss 3, Pp 337-346 (2021)
Resumen: Introducción: Los pacientes con enfermedad renal crónica (ERC) tiene alto riesgo de morbimortalidad cardiovascular. Las alteraciones estructurales cardiacas subclínicas tienen valor pronóstico en estos pacientes. El objetivo fue estudiar
Externí odkaz:
https://doaj.org/article/e2848b8462764eef9fb9f21ec7afd776
Autor:
Sonia Mota-Zamorano, Nicolás R. Robles, Luz M. González, José M. Valdivielso, Juan Lopez-Gomez, Bárbara Cancho, Guadalupe García-Pino, Guillermo Gervasini
Publikováno v:
Journal of Clinical Medicine, Vol 10, Iss 17, p 3980 (2021)
Genes in the epoxygenase pathway of arachidonic acid metabolism leading to vasoactive eicosanoids, mainly 20-hydroxyeicosatetraenoic (20-HETE) and epoxyeicosatrienoic (EETs) acids, have been related to glucose-induced renal damage in preclinical repo
Externí odkaz:
https://doaj.org/article/eef38083151d4db38162fa20e5f2b814
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 8, p 3887 (2021)
Renal fibrosis is a complex disorder characterized by the destruction of kidney parenchyma. There is currently no cure for this devastating condition. Extracellular vesicles (EVs) are membranous vesicles released from cells in both physiological and
Externí odkaz:
https://doaj.org/article/a74a013a577b44588db197f7b07d3d14
Autor:
Joan Valls, Serafí Cambray, Carles Pérez-Guallar, Milica Bozic, Marcelino Bermúdez-López, Elvira Fernández, Àngels Betriu, Isabel Rodríguez, José M. Valdivielso
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Chronic kidney disease (CKD) is a major risk factor for end-stage renal disease, cardiovascular disease and premature death. Despite classical clinical risk factors for CKD and some genetic risk factors have been identified, the residual risk observe
Externí odkaz:
https://doaj.org/article/5d568a5e83374b9f8695d89ef4595fce
Autor:
Mercè Borràs, Serafí Cambray, Maria Crespo-Masip, Miguel Pérez-Fontán, Milica Bozic, Marcelino Bermudez-López, Elvira Fernández, Àngels Betriu, José M. Valdivielso
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Carotid intima media thickness (cIMT) displays prognostic value as a marker of cardiovascular risk in dialysis patients. However, few data are available regarding the impact of dialysis modality on cIMT. The aim of this study is to determine whether
Externí odkaz:
https://doaj.org/article/d37cb437c43140489cf2e85cc830f6bf
Publikováno v:
Biomolecules, Vol 10, Iss 7, p 1051 (2020)
N-Methyl-d-aspartate receptor (NMDAR) is a glutamate-gated ionotropic receptor that intervenes in most of the excitatory synaptic transmission within the central nervous system (CNS). Aside from being broadly distributed in the CNS and having indispe
Externí odkaz:
https://doaj.org/article/f1f0e04d4f064d119cff76d6ee077ded
Autor:
Serafí Cambray, Rajesh Kumar Galimudi, Milica Bozic, Marcelino Bermúdez-López, Isabel Rodríguez, José M. Valdivielso
Publikováno v:
Journal of Clinical Medicine, Vol 8, Iss 5, p 592 (2019)
Chronic kidney disease (CKD) is associated with a higher risk of cardiovascular events (CVE), partly due to the higher burden of atherosclerosis. Circulating Osteopontin (OPN) levels have been also shown to have a potential role in the development of
Externí odkaz:
https://doaj.org/article/c8d75856fcbf40d7ae9239022f030999
Autor:
Patrick B Mark, Juan J Carrero, Kunihiro Matsushita, Yingying Sang, Shoshana H Ballew, Morgan E Grams, Josef Coresh, Aditya Surapaneni, Nigel J Brunskill, John Chalmers, Lili Chan, Alex R Chang, Rajkumar Chinnadurai, Gabriel Chodick, Massimo Cirillo, Dick de Zeeuw, Marie Evans, Amit X Garg, Orlando M Gutierrez, Hiddo J L Heerspink, Gunnar H Heine, William G Herrington, Junichi Ishigami, Florian Kronenberg, Jun Young Lee, Adeera Levin, Rupert W Major, Angharad Marks, Girish N Nadkarni, David M J Naimark, Christoph Nowak, Mahboob Rahman, Charumathi Sabanayagam, Mark Sarnak, Simon Sawhney, Markus P Schneider, Varda Shalev, Jung-Im Shin, Moneeza K Siddiqui, Nikita Stempniewicz, Keiichi Sumida, José M Valdivielso, Jan van den Brand, Angela Yee-Moon Wang, David C Wheeler, Lihua Zhang, Frank L J Visseren, Benedicte Stengel
Publikováno v:
European Heart Journal. 44(13):1157-1166
Aims Chronic kidney disease (CKD) increases risk of cardiovascular disease (CVD). Less is known about how CVD associates with future risk of kidney failure with replacement therapy (KFRT). Methods and results The study included 25 903 761 individuals