Zobrazeno 1 - 10
of 74
pro vyhledávání: '"José M. Saez"'
Publikováno v:
Molecular and Cellular Endocrinology. 179:47-74
Autor:
Pablo Fernandez, Mario M. Zakin, Franck Brunel, Silvia Cereghini, María Arroyo Jimenez, José M. Saez
Publikováno v:
Endocrinology. 141:2392-2400
Studies in Nur77-deficient mice have shown that the basal regulation of hypothalamic and pituitary functions as well as the adrenocortical steroidogenesis in these animals is normal. This indicates that Nur77-related orphan receptors may substitute N
Publikováno v:
Endocrinology. 141:1599-1607
The purpose of this study was to evaluate the time-course effect of a 36-h treatment with ACTH (10−8m), transforming growth factor-β1 (TGFβ1; 10−10m), angiotensin II (AngII; 10−7m), and insulin-like growth factor I (IGF-I; 10−8m) on the ste
Autor:
Patrick Leduque, Karine Maisnier-Patin, Dominique Langlois, José M. Saez, Christine Le Roy, J Yuan Li
Publikováno v:
Molecular and Cellular Endocrinology. 158:87-98
Transforming growth factor beta (TGFbeta) has been reported to be a potent growth inhibitor of epithelial cells. The purpose of the present work was to study in vitro and in vivo the effects of overexpression of a dominant-negative type II TGFbeta re
Publikováno v:
Endocrinology. 140:4988-4994
The regulatory effects of angiotensin-II (AngII) and several growth factors, including insulin-like growth factor 1 (IGF-1), basic fibroblast growth factor (bFGF), and transforming growth factor β1 (TGFβ1) on the AngII subtype 2 (AT2) receptor were
Publikováno v:
Molecular and Cellular Endocrinology. 139:61-69
Previous studies have suggested that the expression of angiotensin type 2 receptor was inversely related to cell proliferation. We examined the effects of insulin-like growth factor (IGF-1), basic fibroblast growth factor (bFGF), transforming growth
Autor:
José M. Saez, Jean-Claude Cuber, Fei Ye, Anne-Marie Chevrier, Jacques Abello, Dominique Langlois, Jean-Alain Chayvialle
Publikováno v:
Hormone Research in Paediatrics. 50:183-189
Receptors for insulin-like growth factors (IGF-I and IGF-II) are expressed in mammalian intestinal epithelium. No information on the presence of IGF receptors in intestinal endocrine cells is available. We tested for IGF-I receptors the endocrine cel
Publikováno v:
Endocrinology. 138:4783-4791
In addition to the regulation of FSH secretion, it has been clearly shown that inhibin and activin have paracrine/autocrine effects in the gonads. We have studied the effect of human recombinant inhibin A and human recombinant activin A on immature p
Publikováno v:
Biochemical and Biophysical Research Communications. 238:905-909
Transforming growth factor beta 1 (TGF beta 1) has been reported to be secreted and to act within the somatic cells of the testis. We examined whether the TGF beta 1 expression is present at mRNA and protein levels in purified rat Sertoli cells (SC),
Autor:
José M. Saez, François Ballet, E Gomez, Bernard Jégou, Hervé Lejeune, Eugène Bosmans, Corinne Cudicini
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 82:1426-1433
Interleukins (IL)-1 and -6 have been shown to be produced by several categories of cells in the rat testis and involved in the paracrine control of testicular function. Evidence of high amounts of IL-1 have been shown in the human testis, but nothing