The Current Status and Work of Three Rs Centres and Platforms in Europe*

Autor: Winfried Neuhaus, Birgit Reininger-Gutmann, Beate Rinner, Roberto Plasenzotti, Doris Wilflingseder, Joery De Kock, Tamara Vanhaecke, Vera Rogiers, Dagmar Jírová, Kristina Kejlová, Lisbeth E. Knudsen, Rasmus Normann Nielsen, Burkhard Kleuser, Vivian Kral, Christa Thöne-Reineke, Thomas Hartung, Giorgia Pallocca, Costanza Rovida, Marcel Leist, Stefan Hippenstiel, Annemarie Lang, Ida Retter, Stephanie Krämer, Peter Jedlicka, Katharina Ameli, Ellen Fritsche, Julia Tigges, Eliška Kuchovská, Manuela Buettner, Andre Bleich, Nadine Baumgart, Jan Baumgart, Marcus W. Meinhardt, Rainer Spanagel, Sabine Chourbaji, Bettina Kränzlin, Bettina Seeger, Maren von Köckritz-Blickwede, José M. Sánchez-Morgado, Viola Galligioni, Daniel Ruiz-Pérez, Dania Movia, Adriele Prina-Mello, Arti Ahluwalia, Valeria Chiono, Arno C. Gutleb, Marthe Schmit, Bea van Golen, Leane van Weereld, Anne Kienhuis, Erica van Oort, Jan van der Valk, Adrian Smith, Joanna Roszak, Maciej Stępnik, Zuzanna Sobańska, Edyta Reszka, I. Anna S. Olsson, Nuno Henrique Franco, Bogdan Sevastre, Helena Kandarova, Sara Capdevila, Jessica Johansson, Emma Svensk, Christopher R. Cederroth, Jenny Sandström, Ian Ragan, Nataliia Bubalo, Jens Kurreck, Horst Spielmann

Publikováno v: Alternatives to Laboratory Animals. 50:381-413

The adoption of Directive 2010/63/EU on the protection of animals used for scientific purposes has given a major push to the formation of Three Rs initiatives in the form of centres and platforms. These centres and platforms are dedicated to the so-c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc36c6df121407af00ec21546f6f685f
https://doi.org/10.1177/02611929221140909

The Rise of Three Rs Centres and Platforms in Europe

Autor: Winfried Neuhaus, Birgit Reininger-Gutmann, Beate Rinner, Roberto Plasenzotti, Doris Wilflingseder, Joery De Kock, Tamara Vanhaecke, Vera Rogiers, Dagmar Jírová, Kristina Kejlová, Lisbeth E. Knudsen, Rasmus Normann Nielsen, Burkhard Kleuser, Vivian Kral, Christa Thöne-Reineke, Thomas Hartung, Giorgia Pallocca, Marcel Leist, Stefan Hippenstiel, Annemarie Lang, Ida Retter, Stephanie Krämer, Peter Jedlicka, Katharina Ameli, Ellen Fritsche, Julia Tigges, Manuela Buettner, Andre Bleich, Nadine Baumgart, Jan Baumgart, Marcus W. Meinhardt, Rainer Spanagel, Sabine Chourbaji, Bettina Kränzlin, Bettina Seeger, Maren von Köckritz-Blickwede, José M. Sánchez-Morgado, Viola Galligioni, Daniel Ruiz-Pérez, Dania Movia, Adriele Prina-Mello, Arti Ahluwalia, Valeria Chiono, Arno C. Gutleb, Marthe Schmit, Bea van Golen, Leane van Weereld, Anne Kienhuis, Erica van Oort, Jan van der Valk, Adrian Smith, Joanna Roszak, Maciej Stępnik, Zuzanna Sobańska, I. Anna S. Olsson, Nuno Henrique Franco, Bogdan Sevastre, Helena Kandarova, Sara Capdevila, Jessica Johansson, Christopher R. Cederroth, Jenny Sandström, Ian Ragan, Nataliia Bubalo, Horst Spielmann

Publikováno v: ATLA-ALTERNATIVES TO LABORATORY ANIMALS
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname

Public awareness and discussion about animal experiments and replacement methods has greatly increased in recent years. The term ‘the Three Rs’, which stands for the Replacement, Reduction and Refinement of animal experiments, is inseparably link

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01736f127bcfc51bf6af214ad3a3d859
https://pubmed.ncbi.nlm.nih.gov/35578444

Animal and Environmental Factors That Influence Reproducibility

Autor: Aurora Brønstad, Kathleen R. Pritchett-Corning, José M. Sánchez-Morgado

Publikováno v: Experimental Design and Reproducibility in Preclinical Animal Studies ISBN: 9783030661465

In this chapter we address factors that may bias experiments and impact results unless they are controlled for. This apply for factors in the environment that the animal interacts with to assure optimal homeostasis or to fulfil basic needs. It also i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::18532502ace534b4d82db4f663d57c85
https://doi.org/10.1007/978-3-030-66147-2_3

Quantification of Hair Corticosterone, DHEA and Testosterone as a Potential Tool for Welfare Assessment in Male Laboratory Mice

Autor: Martina Bertocchi, Maria Laura Bacci, José M. Sánchez-Morgado, Nadia Govoni, Domenico Ventrella, Camilla Aniballi, Alberto Elmi, Viola Galligioni

Publikováno v: Animals, Vol 10, Iss 2408, p 2408 (2020)
Animals
Volume 10
Issue 12
Animals : an Open Access Journal from MDPI

Steroids, providing information regarding several biological patterns including stress and sexual behavior, have been investigated in different matrices in laboratory mice. Data regarding hair quantification, indicative of longer timespans when compa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ea897d0eedb244305a2b336aa76a7c5
https://www.mdpi.com/2076-2615/10/12/2408

Experimental Design and Reproducibility in Preclinical Animal Studies

Autor: José M. Sánchez Morgado, Aurora Brønstad

This highly-readable text provides grounds on how to plan and conduct animal experiments that can be reproduced by others. The book touches on factors that may impact the reproducibility of animal studies including: the animal genetic background,