Zobrazeno 1 - 10
of 28
pro vyhledávání: '"José M. Peregrín-Alvarez"'
Publikováno v:
PLoS Computational Biology, Vol 5, Iss 10, p e1000523 (2009)
Escherichia coli serves as an excellent model for the study of fundamental cellular processes such as metabolism, signalling and gene expression. Understanding the function and organization of proteins within these processes is an important step towa
Externí odkaz:
https://doaj.org/article/d0a5e25c3bd14798bf2065ee7ea09b18
Autor:
Constance A. M. Finney, José M. Peregrín-Alvarez, James D. Wasmuth, John Parkinson, Jennifer Daub
Publikováno v:
Genome Research. 19:1202-1213
The Apicomplexa are a group of phylogenetically related parasitic protists that include Plasmodium, Cryptosporidium, and Toxoplasma. Together they are a major global burden on human health and economics. To meet this challenge, several international
Autor:
Andrew Emili, José M. Peregrín-Alvarez, Sadhna Phanse, John Parkinson, Vincent Fong, Chong Su, Gareth Butland
Publikováno v:
Nucleic Acids Research
High throughput methods are increasingly being used to examine the functions and interactions of gene products on a genome-scale. These include systematic large-scale proteomic studies of protein complexes and protein–protein interaction networks,
Autor:
Geoffrey J. Barton, Jonathan E. Allen, Elisabet Caler, Steven A. Williams, Catherine B. Poole, Mark Blaxter, Qi Zhao, Larry A. McReynolds, Michael C. Schatz, Sara Lustigman, Claire M. Fraser-Liggett, Tamara Feldblyum, Martin Shumway, Thomas R. Unnasch, Ian F Korf, Alan L. Scott, Thomas B. Nutman, David B. Guiliano, Shiliang Wang, Clotilde K. S. Carlow, Todd Creasy, Sandra J. Laney, James P. McCarter, Steven L. Salzberg, Mario Stanke, Diego Miranda-Saavedra, Jennifer Daub, Katherine A. Smith, Deryck J. Williams, David J. Spiro, Tim H. Lindblom, Jinming Jin, Mihaela Pertea, Mehul B. Ganatra, Qinghu Ren, Yinhua Zhang, Sanjay Kumar, Jenna Ware, John Parkinson, Mihai Pop, Arthur L. Delcher, José M. Peregrín-Alvarez, Paolo Amedeo, Gary J. Weil, Wen Li, Barton E. Slatko, Luke J. Tallon, Samuel V. Angiuoli, Hean Koo, William F. Gregory, Ann E. Sluder, Seth Schobel, Crawford Michael J, Jonathan Crabtree, Lori Saunders, Richard Komuniecki, David M. A. Martin, Chris F. Estes, Claude V. Maina, Nicholas M. Johnson, Aguan Wei, Jeremy M. Foster, Dong Ma, Owen White, Jennifer R. Wortman, Ben-Wen Li, Dimmic Matt W, Elodie Ghedin, Najib M. El-Sayed, Brian J. Haas, Makedonka Mitreva
Publikováno v:
Ghedin, E, Wang, S, Spiro, D, Caler, E, Zhao, Q, Crabtree, J, Allen, J E, Delcher, A L, Guiliano, D B, Miranda-Saavedra, D, Angiuoli, S V, Creasy, T, Amedeo, P, Haas, B, El-Sayed, N M, Wortman, J R, Feldblyum, T, Tallon, L, Schatz, M, Shumway, M, Koo, H, Salzberg, S L, Schobel, S, Pertea, M, Pop, M, White, O, Barton, G J, Carlow, C K S, Crawford, M J, Daub, J, Dimmic, M W, Estes, C F, Foster, J M, Ganatra, M, Gregory, W F, Johnson, N M, Jin, J, Komuniecki, R, Korf, I, Kumar, S, Laney, S, Li, B-W, Li, W, Lindblom, T H, Lustigman, S, Ma, D, Maina, C V, Martin, D M A, McCarter, J P, McReynolds, L, Mitreva, M, Nutman, T B, Parkinson, J, Peregrín-Alvarez, J M, Poole, C, Ren, Q, Saunders, L, Sluder, A E, Smith, K, Stanke, M, Unnasch, T R, Ware, J, Wei, A D, Weil, G, Williams, D J, Zhang, Y, Williams, S A, Fraser-Liggett, C, Slatko, B, Blaxter, M L & Scott, A L 2007, ' Draft genome of the filarial nematode parasite Brugia malayi ', Science, vol. 317, no. 5845, pp. 1756-60 . https://doi.org/10.1126/science.1145406
Parasitic nematodes that cause elephantiasis and river blindness threaten hundreds of millions of people in the developing world. We have sequenced the ∼90 megabase (Mb) genome of the human filarial parasite Brugia malayi and predict ∼11,500 prot
Autor:
John Parkinson, Andrei Starostine, Joyce Li, José M. Peregrín-Alvarez, Xiaochun Yang, Veronica Canadien, Andrew Emili, Bryan Beattie, Nevan J. Krogan, Dawn Richards, Jack Greenblatt, Michael Davey, Gareth Butland, Wehong Yang
Publikováno v:
Nature. 433:531-537
Proteins often function as components of multi-subunit complexes. Despite its long history as a model organism, no large-scale analysis of protein complexes in Escherichia coli has yet been reported. To this end, we have targeted DNA cassettes into t
Autor:
Antonio J. Palomares, Francisco M. Cánovas, Mohammed Dary, Miguel A. Caviedes, Ignacio D. Rodríguez-Llorente, José M. Peregrín-Alvarez
Publikováno v:
BMC Systems Biology, Vol 3, Iss 1, p 63 (2009)
BMC Systems Biology
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
BMC Systems Biology
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
Background Rhizobium-Legume symbiosis is an attractive biological process that has been studied for decades because of its importance in agriculture. However, this system has undergone extensive study and although many of the major factors underpinni
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 533
To date the genomes of over 600 organisms have been generated of which 100 are from eukaryotes. Together with partial genome data for an additional 700 eukaryotic organisms, these exceptional sequence resources offer new opportunities to explore phyl
Publikováno v:
Genome Biology
A novel evolutionary analysis of metabolic networks across 26 taxa reveals a highly-conserved but flexible core of metabolic enzymes.
Background Cellular metabolism is a fundamental biological system consisting of myriads of enzymatic reactions
Background Cellular metabolism is a fundamental biological system consisting of myriads of enzymatic reactions
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 453
Phylogenetic profiles describe the presence or absence of a protein in a set of reference genomes. Similarity between profiles is an indicator of functional coupling between gene products: the greater the similarity, the greater the likelihood of pro
Autor:
José M, Peregrín-Alvarez
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 452
With the recent sequencing of numerous complete genomes and the advent of high throughput technologies (e.g., yeast two-hybrid assays or tandem-affinity purification experiments), it is now possible to estimate the ancestral form of protein interacti