Up-regulation of ATP-binding cassette transporters in the THP-1 human macrophage cell line by the antichagasic benznidazole

Autor: Virginia Gabriela Perdomo, Marcelo G. Luquita, María Laura Ruiz, Viviana A. Catania, José M. Pellegrino, Juan Pablo Rigalli

Publikováno v: Memórias do Instituto Oswaldo Cruz
Memórias do Instituto Oswaldo Cruz, Volume: 111, Issue: 11, Pages: 707-711, Published: 24 OCT 2016
Memórias do Instituto Oswaldo Cruz., Vol 111, Iss 11, Pp 707-711

The effect of benznidazole (BZL) on the expression and activity of P-glycoprotein (P-gp, ABCB1) and multidrug resistance-associated protein 2 (MRP2, ABCC2), the two major transporters of endogenous and exogenous compounds, was evaluated in differenti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e48bf924ed571757756c6531222d3393
http://europepmc.org/articles/PMC5125048

Detection of synergistic combinations of Baccharis extracts with Terbinafine against Trichophyton rubrum with high throughput screening synergy assay (HTSS) followed by 3D graphs. Behavior of some of their components

Autor: Susana Zacchino, Maximiliano Sortino, Juan J. Ivancovich, Marcela Raimondi, Laura S. Favier, José M. Pellegrino, María Victoria Rodriguez, Martha Gattuso

Publikováno v: Phytomedicine. 20:1230-1239

Forty four extracts from nine Baccharis spp. from the Caulopterae section were tested in combination with terbinafine against Trichophyton rubrum with the HTSS assay at six different ratios with the aim of detecting those mixtures that produced a ≥

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5beff0b5c7d4bd83cd7995b8a494d92f
https://doi.org/10.1016/j.phymed.2013.06.015

Induction of intestinal multidrug resistance-associated protein 2 (Mrp2) by spironolactone in rats

Autor: María Laura Ruiz, Marcelo G. Luquita, Juan Pablo Rigalli, Aldo D. Mottino, José M. Pellegrino, Enrique J. Sánchez Pozzi, Viviana A. Catania, Silvina Stella Maris Villanueva, Agostina Arias

Publikováno v: European Journal of Pharmacology. 623:103-106

The effect of spironolactone (SL) pretreatment (200micromol/kg b.w./day, 3 consecutive days) on intestinal multidrug resistance-associated protein 2 (Mrp2) was evaluated in rats. A significant increase in protein levels in upper regions of small inte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7bbd3fe1223168109b9914ff5a16edc
https://doi.org/10.1016/j.ejphar.2009.09.014

HEPATIC AND EXTRAHEPATIC SYNTHESIS AND DISPOSITION OF DINITROPHENYL-S-GLUTATHIONE IN BILE DUCT-LIGATED RATS

Autor: Enrique J. Sánchez Pozzi, Viviana A. Catania, Adriana M. Torres, James L. Boyer, Shi-Ying Cai, Carol J. Soroka, Marcelo G. Luquita, María L. Ruiz, Aldo D. Mottino, Silvina Stella Maris Villanueva, José M. Pellegrino

Publikováno v: Drug Metabolism and Disposition. 34:1301-1309

The ability of the kidney and small intestine to synthesize and subsequently eliminate dinitrophenyl-S-glutathione (DNP-SG), a substrate for the multidrug resistance-associated proteins (Mrps), was assessed in bile duct-ligated (BDL) rats 1, 7, and 1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::892c9b1d04d6cef8a4ee2173766134d5
https://doi.org/10.1124/dmd.106.009415

Mechanisms involved in spironolactone-induced choleresis in the rat

Autor: Viviana A. Catania, Enrique J. Sánchez-Pozzi, Silvina Stella Maris Villanueva, Marcelo G. Luquita, Aldo D. Mottino, Fernando A. Crocenzi, Justina E. Ochoa, María L. Ruiz, José M. Pellegrino, Mary Vore

Publikováno v: Biochemical Pharmacology. 69:531-539

The mechanisms involved in spironolactone (SL, 200 micromol/kg body weight, 3 days i.p.)-induced choleresis were explored in vivo by evaluating bile salt export pump (Bsep)-, multidrug resistance-associated protein 2 (Mrp2)-, and anion exchanger 2 (A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::68b8a7bf6c2f51f3f35d447b84a0af6f
https://doi.org/10.1016/j.bcp.2004.10.017