Zobrazeno 1 - 10
of 16
pro vyhledávání: '"José M. Ligos"'
Autor:
José M. Benito, Daniel Jiménez-Carretero, Clara Restrepo, José M. Ligos, Jaime Valentín-Quiroga, Ignacio Mahillo, Alfonso Cabello, Eduardo López-Collazo, Fátima Sánchez-Cabo, Miguel Górgolas, Vicente Estrada, Norma Rallón
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 5937 (2024)
Elite controllers (ECs) are people living with HIV (PLWH) able to control HIV replication without antiretroviral therapy and have been proposed as a model of a functional HIV cure. Much evidence suggests that this spontaneous control of HIV has a cos
Externí odkaz:
https://doaj.org/article/a51c172248724682b4805792705b6363
Autor:
José M. Benito, María C. Ortiz, Agathe León, Luis A. Sarabia, José M. Ligos, María Montoya, Marcial Garcia, Ezequiel Ruiz-Mateos, Rosario Palacios, Alfonso Cabello, Clara Restrepo, Carmen Rodriguez, Jorge del Romero, Manuel Leal, María A. Muñoz-Fernández, José Alcamí, Felipe García, Miguel Górgolas, Norma Rallón, On behalf of ECRIS integrated in the Spanish AIDS Research Network
Publikováno v:
BMC Medicine, Vol 16, Iss 1, Pp 1-12 (2018)
Abstract Background Despite long-lasting HIV replication control, a significant proportion of elite controller (EC) patients may experience CD4 T-cell loss. Discovering perturbations in immunological parameters could help our understanding of the mec
Externí odkaz:
https://doaj.org/article/03d5b5b4d6f8419c8c20967eec6cee93
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Hematopoietic stem and progenitor cell (HSPCs) proliferation is controlled by signals from the niche. Here, Leivaet al. show in vivoin mice that deletion of E-selectin ligand 1 causes quiescence of HSPCs and a reduction in niche size, which is mediat
Externí odkaz:
https://doaj.org/article/590357cb8e5242c5a6fe807145cf27d3
Autor:
María A Navarrete-Muñoz, Clara Restrepo, Marcial García, Miguel Górgolas, Sara Nistal, Jose Luis Valencia, Norma Rallón, Laura Prieto, María C. Montoya, Beatriz Alvarez, José M. Benito, José M. Ligos, Alfonso Cabello
Publikováno v:
Journal of Clinical Medicine
Repisalud
Instituto de Salud Carlos III (ISCIII)
Biblos-e Archivo: Repositorio Institucional de la UAM
Universidad Autónoma de Madrid
E-Prints Complutense. Archivo Institucional de la UCM
instname
Journal of Clinical Medicine, Vol 9, Iss 2978, p 2978 (2020)
Volume 9
Issue 9
Biblos-e Archivo. Repositorio Institucional de la UAM
Repisalud
Instituto de Salud Carlos III (ISCIII)
Biblos-e Archivo: Repositorio Institucional de la UAM
Universidad Autónoma de Madrid
E-Prints Complutense. Archivo Institucional de la UCM
instname
Journal of Clinical Medicine, Vol 9, Iss 2978, p 2978 (2020)
Volume 9
Issue 9
Biblos-e Archivo. Repositorio Institucional de la UAM
(1) Background: The role of hepatitis C virus (HCV) co-infection on the T-cell homeostasis disturbances in human immunodeficiency virus (HIV)-infected patients as well as its reversion after HCV eradication with direct acting antivirals (DAAs) therap
Autor:
David Sancho, José M. Ligos, Daniel Jimenez-Carretero, María Martínez-López, María C. Montoya
Publikováno v:
The Journal of Immunology. 200:3319-3331
Advances in flow cytometry (FCM) increasingly demand adoption of computational analysis tools to tackle the ever-growing data dimensionality. In this study, we tested different data input modes to evaluate how cytometry acquisition configuration and
Autor:
Ángel F. Álvarez-Prado, Almudena R. Ramiro, Niels Galjart, José M. Ligos, Ester Marina-Zárate, Arantxa Pérez-García
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Nature Communications
Nature Communications, 8:16067. Nature Publishing Group
Repisalud
Instituto de Salud Carlos III (ISCIII)
Nature Communications
Nature Communications, 8:16067. Nature Publishing Group
Repisalud
Instituto de Salud Carlos III (ISCIII)
In germinal centres (GC) mature B cells undergo intense proliferation and immunoglobulin gene modification before they differentiate into memory B cells or long-lived plasma cells (PC). GC B-cell-to-PC transition involves a major transcriptional swit
Autor:
María A Navarrete-Muñoz, Manuel L. Fernández-Guerrero, José M. Ligos, Marcial García, Alfonso Cabello, Norma Rallón, Francisco Javier de la Hera, José M. Benito, Vicente Estrada, Juan Carlos López-Bernaldo, Miguel Górgolas, Carlos Barros, Clara Restrepo, María C. Montoya
Publikováno v:
Scientific Reports
Repisalud
Instituto de Salud Carlos III (ISCIII)
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Scientific Reports, Vol 8, Iss 1, Pp 1-8 (2018)
Repisalud
Instituto de Salud Carlos III (ISCIII)
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Scientific Reports, Vol 8, Iss 1, Pp 1-8 (2018)
A recent study has pointed out to CD32a as a potential biomarker of HIV-persistent CD4 cells. We have characterized the level and phenotype of CD32+ cells contained in different subsets of CD4 T-cells and its potential correlation with level of total
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9573de0690cfb041967e36601aca25e
https://hdl.handle.net/20.500.12105/6662
https://hdl.handle.net/20.500.12105/6662
Autor:
Vicente Estrada, María C. Montoya, Carlos Barros, José Miguel Benito, Manuel L. Fernández-Guerrero, Marcial García, Juan Carlos López-Bernaldo, Alfonso Cabello, Norma Rallón, Francisco Javier de la Hera, Miguel Górgolas, José M. Ligos
Publikováno v:
Repisalud
Instituto de Salud Carlos III (ISCIII)
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Scientific Reports, Vol 7, Iss 1, Pp 1-7 (2017)
Scientific Reports
Instituto de Salud Carlos III (ISCIII)
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Scientific Reports, Vol 7, Iss 1, Pp 1-7 (2017)
Scientific Reports
HIV latency is the main barrier to HIV eradication. Peripheral T follicular helper (pTfh) cells have a prominent role in HIV persistence. Herein, we analyzed the HIV reservoir size within memory CD4+ T-cell subsets in patients with HIV replication co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23ec891f54edaf59c77bb31c31d9ae1b
https://hdl.handle.net/20.500.12105/7210
https://hdl.handle.net/20.500.12105/7210
Autor:
Orlando Domínguez, Antonio Herrera-Merchan, Susana González, José M. Ligos, A de Molina, Lorena Arranz
Publikováno v:
Nature Communications
Recent evidence shows increased and decreased expression of Ezh2 in cancer, suggesting a dual role as an oncogene or tumour suppressor. To investigate the mechanism by which Ezh2-mediated H3K27 methylation leads to cancer, we generated conditional Ez
Autor:
I. Hidalgo, Javier Nuñez, José M. Ligos, Antonio Herrera-Merchan, Fernando Martínez, Orlando Domínguez, Laura Carramolino, Miguel Torres, Susana González
Publikováno v:
Cell Stem Cell. 11:649-662
SummaryPolycomb group (PcG) proteins are key epigenetic regulators of hematopietic stem cell (HSC) fate. The PcG members Ezh2 and Ezh1 are important determinants of embryonic stem cell identity, and the transcript levels of these histone methyltransf