Zobrazeno 1 - 10
of 18
pro vyhledávání: '"José M. Brito"'
Autor:
Anny Devoy, Georgia Price, Francesca De Giorgio, Rosie Bunton-Stasyshyn, David Thompson, Samanta Gasco, Alasdair Allan, Gemma F. Codner, Remya R. Nair, Charlotte Tibbit, Ross McLeod, Zeinab Ali, Judith Noda, Alessandro Marrero-Gagliardi, José M. Brito-Armas, Muhammet M. Öztürk, Michelle Simon, Edward O’Neill, Sam Bryce-Smith, Jackie Harrison, Gemma Atkins, Silvia Corrochano, Michelle Stewart, Lydia Teboul, Abraham Acevedo-Arozena, Elizabeth M.C. Fisher, Thomas J. Cunningham
Publikováno v:
iScience, Vol 25, Iss 4, Pp 103999- (2022)
Externí odkaz:
https://doaj.org/article/b6e675c7a1d040dd9354ef6662434d04
Autor:
Anny Devoy, Georgia Price, Francesca De Giorgio, Rosie Bunton-Stasyshyn, David Thompson, Samanta Gasco, Alasdair Allan, Gemma F. Codner, Remya R. Nair, Charlotte Tibbit, Ross McLeod, Zeinab Ali, Judith Noda, Alessandro Marrero-Gagliardi, José M. Brito-Armas, Muhammet M. Öztürk, Michelle Simon, Edward O'Neill, Sam Bryce-Smith, Jackie Harrison, Gemma Atkins, Silvia Corrochano, Michelle Stewart, Lydia Teboul, Abraham Acevedo-Arozena, Elizabeth M.C. Fisher, Thomas J. Cunningham
Publikováno v:
iScience, Vol 24, Iss 12, Pp 103463- (2021)
Summary: Amyotrophic lateral sclerosis/frontotemporal dementia (ALS/FTD) is a fatal neurodegenerative disorder, and continued innovation is needed for improved understanding and for developing therapeutics. We have created next-generation genomically
Externí odkaz:
https://doaj.org/article/5af44f859e954ddaba09b5e693fc05a6
Autor:
Ingrid R. Cordeiro, Daiana V. Lopes, José G. Abreu, Katia Carneiro, Maria I. D. Rossi, José M. Brito
Publikováno v:
Biology Open, Vol 4, Iss 9, Pp 1180-1193 (2015)
Human adipose-derived stromal cells (hADSC) are a heterogeneous cell population that contains adult multipotent stem cells. Although it is well established that hADSC have skeletal potential in vivo in adult organisms, in vitro assays suggest further
Externí odkaz:
https://doaj.org/article/29822a5ca25c40d9986b999da6e57d74
Akademický článek
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Autor:
Juan M. Godoy-Corchuelo, Zeinab Ali, Jose M. Brito Armas, Aurea B. Martins-Bach, Irene García-Toledo, Luis C. Fernandez-Beltrán, Juan I. Lopez-Carbonero, Pablo Bascunana, Shoshana Spring, Irene Jimenez-Coca, Ramón A. Muñozde Bustillo Alfaro, Maria J. Sanchez-Barrena, Remya R. Nair, Brian J. Nieman, Jason P. Lerch, Karla L. Miller, Hande P. Ozdinler, Elizabeth M.C. Fisher, Thomas J. Cunningham, Abraham Acevedo-Arozena, Silvia Corrochano
Publikováno v:
Neurobiology of Disease, Vol 202, Iss , Pp 106708- (2024)
Externí odkaz:
https://doaj.org/article/418fc08c4bb144dfbd73a56508341368
Autor:
Samanta Gasco, Gemma Atkins, Anny Devoy, David C. Thompson, Zeinab Ali, Michelle Simon, Elizabeth M. C. Fisher, Abraham Acevedo-Arozena, Alessandro Marrero-Gagliardi, Thomas J. Cunningham, Jackie Harrison, Edward O’Neill, José M. Brito-Armas, Alasdair J Allan, Michelle Stewart, Ross McLeod, Charlotte Tibbit, Gemma F. Codner, Francesca De Giorgio, Remya R. Nair, Silvia Corrochano, Lydia Teboul, Judith Noda, Georgia Price, Rosie K. A. Bunton-Stasyshyn
SUMMARYAmyotrophic lateral sclerosis - frontotemporal dementia spectrum disorder (ALS/FTD) is a complex neurodegenerative disease; up to 10% of cases are familial, usually arising from single dominant mutations in >30 causative genes. Transgenic mous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3dfa0375983fbaf85a49127de1182d75
https://doi.org/10.1101/2021.07.05.451113
https://doi.org/10.1101/2021.07.05.451113
Autor:
Luana C Farnesi, José M Brito, Jutta G Linss, Marcelo Pelajo-Machado, Denise Valle, Gustavo L Rezende
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30363 (2012)
Population control of the dengue vector mosquito, Aedes aegypti, is difficult due to many reasons, one being the development of resistance to neurotoxic insecticides employed. The biosynthesis of chitin, a major constituent of insect cuticle, is a no
Externí odkaz:
https://doaj.org/article/7ae5e60a4f464dbc9d6aecb4fb70022b
Autor:
Juan M. Godoy-Corchuelo, Zeinab Ali, Jose M. Brito Armas, Aurea B. Martins-Bach, Irene García-Toledo, Luis C. Fernández-Beltrán, Juan I. López-Carbonero, Pablo Bascuñana, Shoshana Spring, Irene Jimenez-Coca, Ramón A. Muñoz de Bustillo Alfaro, Maria J. Sánchez-Barrena, Remya R. Nair, Brian J. Nieman, Jason P. Lerch, Karla L. Miller, Hande P. Ozdinler, Elizabeth M.C. Fisher, Thomas J. Cunningham, Abraham Acevedo-Arozena, Silvia Corrochano
Publikováno v:
Neurobiology of Disease, Vol 193, Iss , Pp 106437- (2024)
TDP-43 pathology is found in several neurodegenerative disorders, collectively referred to as “TDP-43 proteinopathies”. Aggregates of TDP-43 are present in the brains and spinal cords of >97% of amyotrophic lateral sclerosis (ALS), and in brains
Externí odkaz:
https://doaj.org/article/76599e797bbd49ac8a63e0a6d72160dc
Autor:
David E. Housman, Prasanth Sivakumar, Martina Hallegger, Cristian Bodo, Bernadett Kalmar, Warren Emmett, Hugo Alexandre Mendes Oliveira, Philip Stanier, Adrian M. Isaacs, Alexander E. Conicella, Linda Greensmith, Lydia Teboul, Pietro Fratta, Alessandro Marrero-Gagliardi, Vincent Plagnol, Nicolas L. Fawzi, José M. Brito-Armas, Nicol Birsa, Yichao Yu, Erwin Pauws, Emma Peskett, Joffrey Mianné, Agnieszka M. Ule, Gemma F. Codner, T. Ricketts, Andrea Calvo, Silvia Corrochano, Toby Collins, Jack Humphrey, M Groves, Mark F. Lythgoe, Emanuele Buratti, Francisco E. Baralle, Eric T. Wang, Adriano Chiò, Alan Mejia Maza, Michelle Stewart, Yoichi Gondo, Ryutaro Fukumura, Kitty Lo, Elizabeth M. C. Fisher, Abraham Acevedo-Arozena
Publikováno v:
The EMBO Journal
EMBRO Press
EMBRO Press
TDP-43 (encoded by the gene TARDBP) is an RNA binding protein central to the pathogenesis of amyotrophic lateral sclerosis (ALS). However, how TARDBP mutations trigger pathogenesis remains unknown. Here, we use novel mouse mutants carrying point muta
Publikováno v:
Revista espanola de geriatria y gerontologia. 53(1)
Alzheimer's disease is the most common cause of dementia in the elderly population. Currently, there are no effective treatments to prevent or delay the natural course of the disease. Numerous studies have provided information about the molecular pro