Zobrazeno 1 - 10
of 35
pro vyhledávání: '"José M Muñoz‐Félix"'
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 2, Pp 1-2 (2019)
Abstract Pathological angiogenesis contributes to tumour progression as well as to chronic inflammatory diseases. In this issue of EMBO Molecular Medicine, Esteban and co‐workers identify endothelial cell MT1‐MMP as a key regulator of intussuscep
Externí odkaz:
https://doaj.org/article/3acbc696ba2e4167ac0ce71b2c4c8860
Autor:
Bárbara Oujo, José M Muñoz-Félix, Miguel Arévalo, Elena Núñez-Gómez, Lucía Pérez-Roque, Miguel Pericacho, María González-Núñez, Carmen Langa, Carlos Martínez-Salgado, Fernando Perez-Barriocanal, Carmelo Bernabeu, José M Lopez-Novoa
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e110365 (2014)
Transforming growth factor-β (TGF-β) plays a pivotal role in renal fibrosis. Endoglin, a 180 KDa membrane glycoprotein, is a TGF-β co-receptor overexpressed in several models of chronic kidney disease, but its function in renal fibrosis remains un
Externí odkaz:
https://doaj.org/article/afc1c5af650941a680ac8824e3fe9421
Autor:
Carlos Martínez-Salgado, Fernando Sánchez-Juanes, Francisco J. López-Hernández, José M. Muñoz-Félix
Publikováno v:
Frontiers in pharmacology. 13
Renal tubulo-interstitial fibrosis is characterized by the excessive accumulation of extracellular matrix (ECM) in the tubular interstitium during chronic kidney disease. The main source of ECM proteins are emerging and proliferating myofibroblasts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23f234b8a39e038bac8ba6202b40ab39
https://pubmed.ncbi.nlm.nih.gov/35770075
https://pubmed.ncbi.nlm.nih.gov/35770075
Autor:
Ana Rita Pedrosa, Emma Newport, Alexandra Njegic, José M. Muñoz-Félix, Kairbaan Hodivala-Dilke
Publikováno v:
Cancers, Vol 13, Iss 5207, p 5207 (2021)
Cancers
Cancers
Simple Summary Although immunotherapy has given the highest rate of improvement in cancer treatment in recent years, there is an urgent need to further improve its efficacy. Numerous strategies aim to transform non-responsive, immunosuppressive tumou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e644c50d8ff8eda2ceafbda2994f627
https://www.mdpi.com/2072-6694/13/20/5207
https://www.mdpi.com/2072-6694/13/20/5207
Publikováno v:
Cancers, Vol 13, Iss 5412, p 5412 (2021)
Cancers
Cancers
Simple Summary The modulation of tumor blood vessels is a great opportunity for improving cancer therapies. Understanding the cellular and molecular players that regulate the biology of tumor blood vessels and tumor angiogenesis is necessary for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc3c9f5e64c308f429167ae7c8490050
https://www.mdpi.com/2072-6694/13/21/5412
https://www.mdpi.com/2072-6694/13/21/5412
Publikováno v:
Genes, Vol 12, Iss 800, p 800 (2021)
Genes
Genes
Many different regulatory mechanisms of renal fibrosis are known to date, and those related to transforming growth factor-β1 (TGF-β1)-induced signaling have been studied in greater depth. However, in recent years, other signaling pathways have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4883bd4a032267a0b4054a8c99711ef
https://www.mdpi.com/2073-4425/12/6/800
https://www.mdpi.com/2073-4425/12/6/800
Publikováno v:
EMBO Molecular Medicine
EMBO Molecular Medicine, Vol 12, Iss 2, Pp n/a-n/a (2020)
EMBO Molecular Medicine, Vol 12, Iss 2, Pp n/a-n/a (2020)
Pathological angiogenesis contributes to tumour progression as well as to chronic inflammatory diseases. In this issue of EMBO Molecular Medicine, Esteban and co‐workers identify endothelial cell MT1‐MMP as a key regulator of intussusceptive angi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50e024d9a3708afebf9dbb77c51142be
http://europepmc.org/articles/PMC7005529
http://europepmc.org/articles/PMC7005529
Autor:
Michael Weinmüller, Luciana Marinelli, Adi Schumacher, Horst Kessler, Udaya Kiran Marelli, Joseph Fanous, José M. Muñoz-Félix, Florian Reichart, Andreas F. B. Räder, Tobias G. Kapp, Amnon Hoffman, Chaim Gilon, Kairbaan Hodivala-Dilke, Florian Rechenmacher, Ettore Novellino, Francesco Saverio Di Leva
Publikováno v:
Angewandte Chemie. 129:16624-16629
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eef2c89844fa235ca4a8d1d0c0a0cda5
https://doi.org/10.1002/ange.201709709
https://doi.org/10.1002/ange.201709709
Autor:
Mark Duggan, Kairbaan Hodivala-Dilke, Rei Okamoto, Barry S. Coller, Yuta Tanaka, Thomas Walz, Michael Foley, Marta Filizola, Ryoma Hara, Kazuyoshi Aso, José M. Muñoz-Félix, Yixiao Zhang, Steven L. Teitelbaum, Takeshi Yasui, Roger D. Vaughan, Lorena Buitrago, Johannes van Agthoven, Junichi Takagi, Wei Zou, Yoshiyuki Fukase, Yi Shang, Toshihiro Imaeda, Dragana Nesic, Charles Locuson, Takashi Nakahata, Jihong Li, M. Amin Arnaout, Yuchen Zhou
Publikováno v:
ACS Pharmacol Transl Sci
[Image: see text] The integrin αVβ3 receptor has been implicated in several important diseases, but no antagonists are approved for human therapy. One possible limitation of current small-molecule antagonists is their ability to induce a major conf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aa354737d3d71adbf737c1ecc5f3514
https://pubmed.ncbi.nlm.nih.gov/32259072
https://pubmed.ncbi.nlm.nih.gov/32259072
Autor:
Francisco J. López-Hernández, Carlos Martínez-Salgado, Cristina Cuesta, José M. López-Novoa, Nuria Perretta-Tejedor, Mariela Subileau, José M. Muñoz-Félix
Publikováno v:
Cellular Signalling. 28:1252-1261
Upregulated synthesis of extracellular matrix (ECM) proteins by myofibroblasts is a common phenomenon in the development of fibrosis. Although the role of TGF-β in fibrosis development has been extensively studied, the involvement of other members o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ea875241183208583fc36f19b827110
https://doi.org/10.1016/j.cellsig.2016.05.015
https://doi.org/10.1016/j.cellsig.2016.05.015