Zobrazeno 1 - 10
of 81
pro vyhledávání: '"José M Juiz"'
Autor:
Juan Carlos Alvarado, Verónica Fuentes-Santamaría, Zaskya Benítez-Maicán, Carmen María Díaz García, María Cruz Gabaldón Ull, José M. Juiz
Publikováno v:
Heliyon, Vol 10, Iss 22, Pp e40314- (2024)
The goal of the present study was to determine, through a detailed study of the auditory brainstem response (ABR) waves, the possible existence of an early functional marker for the onset of presbycusis in an animal model. Toward this goal, Wistar ra
Externí odkaz:
https://doaj.org/article/c023a1a5120744e2aff2ea942d1bb42b
Autor:
Pedro Melgar-Rojas, Juan Carlos Alvarado, Verónica Fuentes-Santamaría, María Cruz Gabaldón-Ull, José M Juiz
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138027 (2015)
The reverse transcriptase-quantitative polymerase chain reaction (RT-qPCR) requires adequate normalization in order to ensure accurate results. The use of reference genes is the most common method to normalize RT-qPCR assays; however, many studies ha
Externí odkaz:
https://doaj.org/article/e149e0cee23e4c7b8f6de82990cd900e
Autor:
Liliana Carles, Alejandro Gibaja, Verena Scheper, Juan C. Alvarado, Carlos Almodovar, Thomas Lenarz, José M. Juiz
Publikováno v:
Antioxidants, Vol 13, Iss 7, p 761 (2024)
Cisplatin is an election chemotherapeutic agent used for many cancer treatments. Its cytotoxicity against neoplastic cells is mirrored by that taking place in healthy cells and tissues, resulting in serious adverse events. A very frequent one is otot
Externí odkaz:
https://doaj.org/article/cd91dc9508804f3fa564c1eaeefbfe99
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2023)
Externí odkaz:
https://doaj.org/article/777ea497570946a6862da5ebec6db40d
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2022)
As it is well known, a worldwide improvement in life expectancy has taken place. This has brought an increase in chronic pathologies associated with aging. Cardiovascular, musculoskeletal, psychiatric, and neurodegenerative conditions are common in e
Externí odkaz:
https://doaj.org/article/1bc90137293a43919de15a8beebe967c
Publikováno v:
Antioxidants, Vol 11, Iss 9, p 1759 (2022)
Kanamycin and cisplatin are ototoxic drugs. The mechanisms are incompletely known. With subcutaneous kanamycin (400 mg/kg, 15 days), auditory threshold shifts were detected at days 12–13 at 16 and 32 kHz, extending to 8 and 4 kHz at days 14–15. T
Externí odkaz:
https://doaj.org/article/911e941295dc49fe8f8eec86cce2010c
Autor:
Juan C. Alvarado, Verónica Fuentes-Santamaría, Pedro Melgar-Rojas, María C. Gabaldón-Ull, José J. Cabanes-Sanchis, José M. Juiz
Publikováno v:
Antioxidants, Vol 9, Iss 12, p 1177 (2020)
Noise induces oxidative stress in the cochlea followed by sensory cell death and hearing loss. The proof of principle that injections of antioxidant vitamins and Mg2+ prevent noise-induced hearing loss (NIHL) has been established. However, effectiven
Externí odkaz:
https://doaj.org/article/d1d36d9827d54eaf8d32b799dae5191b
Autor:
Verónica, Fuentes-Santamaría, Juan Carlos, Alvarado, Susana, Mellado, Pedro, Melgar-Rojas, María Cruz, Gabaldón-Ull, José J, Cabanes-Sanchis, José M, Juiz
Publikováno v:
Frontiers in Aging Neuroscience. 14
We have previously reported that young adult rats exposed to daily, short-duration noise for extended time periods, develop accelerated presbycusis starting at 6 months of age. Auditory aging is associated with progressive hearing loss, cell deterior
Autor:
Miguel A. Merchán, José M. Juiz, Juan Carlos Alvarado, María Llanos Valero, David K. Ryugo, Marianny Pernia, Clara María Poveda
Publikováno v:
Brain Sciences
Volume 10
Issue 1
Brain Sciences, Vol 10, Iss 1, p 35 (2020)
Volume 10
Issue 1
Brain Sciences, Vol 10, Iss 1, p 35 (2020)
Deafness affects the expression and distribution of voltage-dependent potassium channels (Kvs) of central auditory neurons in the short-term, i.e., hours to days, but the consequences in the expression of Kvs after long-term deafness remain unknown.
Autor:
Marianny Pernia, I. Plaza, S. Estevez, Clara María Poveda, Juan Carro, Miguel A. Merchán, José M. Juiz
Publikováno v:
Journal of Comparative Neurology. 525:2677-2689
Cross-modal reorganization in the auditory and visual cortices has been reported after hearing and visual deficits mostly during the developmental period, possibly underlying sensory compensation mechanisms. However, there are very few data on the ex