Zobrazeno 1 - 10
of 24
pro vyhledávání: '"José M Fernández-Real"'
Autor:
Zaida Agüera, Xandra Romero, Jon Arcelus, Isabel Sánchez, Nadine Riesco, Susana Jiménez-Murcia, Jana González-Gómez, Roser Granero, Nuria Custal, Monica Montserrat-Gil de Bernabé, Salomé Tárrega, Rosa M Baños, Cristina Botella, Rafael de la Torre, José C Fernández-García, José M Fernández-Real, Gema Frühbeck, Javier Gómez-Ambrosi, Francisco J Tinahones, Ana B Crujeiras, Felipe F Casanueva, José M Menchón, Fernando Fernández-Aranda
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0143012 (2015)
The restoration of body composition (BC) parameters is considered to be one of the most important goals in the treatment of patients with anorexia nervosa (AN). However, little is known about differences between AN diagnostic subtypes [restricting (A
Externí odkaz:
https://doaj.org/article/f854cd8fb4f74dd9b0ee11752992d935
Autor:
Aina Lluch, Jèssica Latorre, Núria Oliveras-Cañellas, Ana Fernández-Sánchez, José M. Moreno-Navarrete, Anna Castells-Nobau, Ferran Comas, Maria Buxò, José I. Rodríguez-Hermosa, María Ballester, Isabel Espadas, Alejandro Martín-Montalvo, Birong Zhang, You Zhou, Ralph Burkhardt, Marcus Höring, Gerhard Liebisch, Ainara Castellanos-Rubio, Izortze Santin, Asha Kar, Markku Laakso, Päivi Pajukanta, Vesa M. Olkkonen, José M. Fernández-Real, Francisco J. Ortega
Publikováno v:
Molecular Metabolism, Vol 90, Iss , Pp 102040- (2024)
Background: Long non-coding RNAs (lncRNAs) can perform tasks of key relevance in fat cells, contributing, when defective, to the burden of obesity and its sequelae. Here, scrutiny of adipose tissue transcriptomes before and after bariatric surgery (G
Externí odkaz:
https://doaj.org/article/ca620d31a1364335831107541b0e2f56
Autor:
Neus Pueyo, Francisco J Ortega, Josep M Mercader, José M Moreno-Navarrete, Monica Sabater, Sílvia Bonàs, Patricia Botas, Elías Delgado, Wifredo Ricart, María T Martinez-Larrad, Manuel Serrano-Ríos, David Torrents, José M Fernández-Real
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60468 (2013)
CONTEXT: Surfactant protein-D (SP-D) is a primordial component of the innate immune system intrinsically linked to metabolic pathways. We aimed to study the association of single nucleotide polymorphisms (SNPs) affecting SP-D with insulin resistance
Externí odkaz:
https://doaj.org/article/d31ba94b88b8407b85acaccc9d1e4da4
Autor:
Francisco J Ortega, José M Moreno-Navarrete, Dolores Mayas, Eva García-Santos, María Gómez-Serrano, José I Rodriguez-Hermosa, Bartomeu Ruiz, Wifredo Ricart, Francisco J Tinahones, Gema Frühbeck, Belen Peral, José M Fernández-Real
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e33233 (2012)
CONTEXT: Expression and activity of the main lipogenic enzymes is paradoxically decreased in obesity, but the mechanisms behind these findings are poorly known. Breast Cancer 1 (BrCa1) interacts with acetyl-CoA carboxylase (ACC) reducing the rate of
Externí odkaz:
https://doaj.org/article/7ba185e10c294f73b2e20f897c901e65
Autor:
Rafael Pérez-Pérez, Juan A López, Eva García-Santos, Emilio Camafeita, María Gómez-Serrano, Francisco J Ortega-Delgado, Wifredo Ricart, José M Fernández-Real, Belén Peral
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30326 (2012)
Protein expression studies based on the two major intra-abdominal human fat depots, the subcutaneous and the omental fat, can shed light into the mechanisms involved in obesity and its co-morbidities. Here we address, for the first time, the identifi
Externí odkaz:
https://doaj.org/article/b10b85db5ebf4d01ba50221d922bff41
Autor:
Francisco J Ortega, José M Moreno-Navarrete, Gerard Pardo, Monica Sabater, Manuela Hummel, Anna Ferrer, Jose I Rodriguez-Hermosa, Bartomeu Ruiz, Wifredo Ricart, Belen Peral, José M Fernández-Real
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9022 (2010)
BACKGROUND: Potential regulators of adipogenesis include microRNAs (miRNAs), small non-coding RNAs that have been recently shown related to adiposity and differentially expressed in fat depots. However, to date no study is available, to our knowledge
Externí odkaz:
https://doaj.org/article/aadbce41ca69404a9350768d4aed311a
Autor:
Aina Lluch, Jessica Latorre, Angela Serena-Maione, Isabel Espadas, Estefanía Caballano-Infantes, José M. Moreno-Navarrete, Núria Oliveras-Cañellas, Wifredo Ricart, María M. Malagón, Alejandro Martin-Montalvo, Walter Birchmeier, Witold Szymanski, Johannes Graumann, María Gómez-Serrano, Elena Sommariva, José M. Fernández-Real, Francisco J. Ortega
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract Plakophilin-2 (PKP2) is a key component of desmosomes, which, when defective, is known to promote the fibro-fatty infiltration of heart muscle. Less attention has been given to its role in adipose tissue. We report here that levels of PKP2 s
Externí odkaz:
https://doaj.org/article/c9aab534331a4f3fa90b32b90c48e65f
Autor:
Aina Lluch, Sonia R. Veiga, Jèssica Latorre, José M. Moreno-Navarrete, Núria Bonifaci, Van Dien Nguyen, You Zhou, Marcus Höring, Gerhard Liebisch, Vesa M. Olkkonen, David Llobet-Navas, George Thomas, Ruth Rodríguez-Barrueco, José M. Fernández-Real, Sara C. Kozma, Francisco J. Ortega
Publikováno v:
JCI Insight, Vol 7, Iss 14 (2022)
The ribosomal protein S6 kinase 1 (S6K1) is a relevant effector downstream of the mammalian target of rapamycin complex 1 (mTORC1), best known for its role in the control of lipid homeostasis. Consistent with this, mice lacking the S6k1 gene have a d
Externí odkaz:
https://doaj.org/article/fd58ace89a53441583d2cf1df43a3a08
A microRNA cluster controls fat cell differentiation and adipose tissue expansion by regulating SNCG
Autor:
Ruth Rodríguez‐Barrueco, Jessica Latorre, Laura Devis‐Jáuregui, Aina Lluch, Nuria Bonifaci, Francisco J. Llobet, Mireia Olivan, Laura Coll‐Iglesias, Katja Gassner, Meredith L. Davis, José M. Moreno‐Navarrete, Anna Castells‐Nobau, Laura Plata‐Peña, Miki Dalmau‐Pastor, Marcus Höring, Gerhard Liebisch, Vesa M. Olkkonen, Maria Arnoriaga‐Rodríguez, Wifredo Ricart, José M. Fernández‐Real, José M. Silva, Francisco J. Ortega, David Llobet‐Navas
Publikováno v:
Advanced Science, Vol 9, Iss 4, Pp n/a-n/a (2022)
Dipòsit Digital de la UB
Universidad de Barcelona
Dipòsit Digital de la UB
Universidad de Barcelona
The H19X-encoded miR-424(322)/503 cluster regulates multiple cellular functions. Here, it is reported for the first time that it is also a critical linchpin of fat mass expansion. Deletion of this miRNA cluster in mice results in obesity, while incre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd31ca7603b3f84c28bd2b992ec8e2bb
http://hdl.handle.net/2445/189979
http://hdl.handle.net/2445/189979
Autor:
Susana Jiménez-Murcia, Francisco J. Tinahones, Lucero Munguía, Rebeca Barahona San Millan, José M Fernández Real, José Carlos Fernández-García, Fernando Fernández-Aranda, Ana María Gómez-Pérez, Amanda Jiménez, Ana de Hollanda, Emilio Ortega, Isabel Cornejo-Pareja, Alexandre Aguilera Luque
Publikováno v:
European Eating Disorders Review
The COVID-19 pandemic is posing a great challenge worldwide. Its rapid progression has caused thousands of deaths worldwide. Although multiple aspects remain to be clarified, some risk factors associated with a worse prognosis have been identified. T