Endurance training inhibits insulin clearance and IDE expression in Swiss mice.

Autor: José M Costa-Júnior, Sandra M Ferreira, André O Protzek, Gustavo J Santos, Ana P Cappelli, Leonardo R Silveira, Cláudio Zoppi, Camila A M de Oliveira, Antonio C Boschero, Everardo M Carneiro, Luiz F Rezende

Publikováno v: PLoS ONE, Vol 10, Iss 3, p e0118809 (2015)

Endurance training improves peripheral insulin sensitivity in the liver and the skeletal muscle, but the mechanism for this effect is poorly understood. Recently, it was proposed that insulin clearance plays a major role in both glucose homeostasis a

Externí odkaz: https://doaj.org/article/633c6da4abb14cf7aa2d638fbeea94d6

Resistance exercise training improves glucose homeostasis by enhancing insulin secretion in C57BL/6 mice

Autor: Emílio Marconato-Júnior, Lucas Zangerolamo, Antonio C. Boschero, Jean Franciesco Vettorazzi, Gabriela Alves Bronczek, Carine Marmentini, Jaqueline Fernandes de Barros, Gabriela Moreira Soares, Mirian Ayumi Kurauti, José M. Costa-Júnior

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports

Resistance exercise exerts beneficial effects on glycemic control, which could be mediated by exercise-induced humoral factors released in the bloodstream. Here, we used C57Bl/6 healthy mice, submitted to resistance exercise training for 10 weeks. Tr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20421550c6d31730cdcdd53bd90a900d
https://doaj.org/article/171b23e3289a4af4880b949fc27e88b4

Whole body ARHGAP21 reduction improves glucose homeostasis in high‐fat diet obese mice

Autor: Gabriela Moreira Soares, Elis Guimaraes De Azevedo, Everardo M. Carneiro, Lucas Zangerolamo, Antonio C. Boschero, José M. Costa-Júnior, Helena C. Barbosa-Sampaio, Sara T.O. Saad

Publikováno v: Journal of Cellular Physiology. 233:7112-7119

GTPase activating proteins (GAPs) are ubiquitously expressed, and their role in cellular adhesion and membrane traffic processes have been well described. TBC1D1, which is a Rab-GAP, is necessary for adequate glucose uptake by muscle cells, whereas i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1b195f1afc1423756324108fdeec6a9
https://doi.org/10.1002/jcp.26527

Central and peripheral effects of physical exercise without weight reduction in obese and lean mice

Autor: Francine Pereira de Carvalho, Marcela Barthichoto, Sandra Mara Ferreira, Camila Aparecida Machado de Oliveira, José M. Costa-Júnior, Thaís Ludmilla Moretto, Izabelle Dias Benfato

Publikováno v: Bioscience Reports

To investigate the central (hypothalamic) and peripheral effects of exercise without body weight change in diet-induced obesity (DIO). Twelve-week-old male C57Bl/6 mice received a control (C) or a high-fat diet (H). Half of them had free access to ru

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a14724c933da4c16a583f4dea7fb29e
http://europepmc.org/articles/PMC5835714

Augmentedβ-Cell Function and Mass in Glucocorticoid-Treated Rodents Are Associated with Increased Islet Ir-β/AKT/mTOR and Decreased AMPK/ACC and AS160 Signaling

Autor: Everardo M. Carneiro, Jean Franciesco Vettorazzi, Fernanda Ortis, Alex Rafacho, Luiz F. Rezende, André Otávio Peres Protzek, Tiago Gomes Araújo, Gustavo J. Santos, José M. Costa-Júnior, Antonio C. Boschero

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
International Journal of Endocrinology
International Journal of Endocrinology, Vol 2014 (2014)

Glucocorticoid (GC) therapies may adversely cause insulin resistance (IR) that lead to a compensatory hyperinsulinemia due to insulin hypersecretion. The increasedβ-cell function is associated with increased insulin signaling that has the protein ki

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f254f6cf57d8541b8b652dd68049a775
https://doi.org/10.1155/2014/983453