Zobrazeno 1 - 10
of 124
pro vyhledávání: '"José M, Fuentes"'
Publikováno v:
Cell Discovery, Vol 10, Iss 1, Pp 1-14 (2024)
Abstract The etiology of various neurodegenerative disorders that mainly affect the central nervous system including (but not limited to) Alzheimer’s disease, Parkinson’s disease and Huntington’s disease has classically been attributed to neuro
Externí odkaz:
https://doaj.org/article/0340e9507e65438ca80393877d5bae28
Autor:
Javier Ojalvo-Pacheco, Sokhna M. S. Yakhine-Diop, José M. Fuentes, Marta Paredes-Barquero, Mireia Niso-Santano
Publikováno v:
Biology, Vol 13, Iss 4, p 238 (2024)
Huntington’s disease (HD) is an autosomal dominant neurodegenerative disease caused by an expansion of the CAG trinucleotide repeat in exon 1 of the huntingtin (HTT) gene. This expansion leads to a polyglutamine (polyQ) tract at the N-terminal end
Externí odkaz:
https://doaj.org/article/48af2c48b8b84bc3844ba079439145bf
Autor:
José M. Fuentes, Patricia Morcillo
Publikováno v:
Cells, Vol 13, Iss 7, p 609 (2024)
Cardiolipin (CL) is a mitochondria-exclusive phospholipid synthesized in the inner mitochondrial membrane. CL plays a key role in mitochondrial membranes, impacting a plethora of functions this organelle performs. Consequently, it is conceivable that
Externí odkaz:
https://doaj.org/article/6fda05b64c174cc59dc8925af0f6806a
Autor:
Mercedes Blanco-Benítez, Ana Calderón-Fernández, Saray Canales-Cortés, Eva Alegre-Cortés, Elisabet Uribe-Carretero, Marta Paredes-Barquero, Alberto Gimenez-Bejarano, Gema Duque González, Patricia Gómez-Suaga, Juan Ortega-Vidal, Sofía Salido, Joaquín Altarejos, Guadalupe Martínez-Chacón, Mireia Niso-Santano, José M. Fuentes, Rosa A. González-Polo, Sokhna M. S. Yakhine-Diop
Publikováno v:
Molecular & Cellular Oncology, Vol 9, Iss 1 (2022)
Phenolic compounds derived from olive oil have beneficial health properties against cancer, neurodegenerative, and metabolic diseases. Therefore, there are discrepancies in their impact on mitochondrial function that result in changes in oxidative ca
Externí odkaz:
https://doaj.org/article/9687ece4146f48c7af61cb3d204be370
Autor:
Alberto Giménez-Bejarano, Eva Alegre-Cortés, Sokhna M. S. Yakhine-Diop, Patricia Gómez-Suaga, José M. Fuentes
Publikováno v:
Antioxidants, Vol 12, Iss 8, p 1593 (2023)
Repeat expansion diseases are a group of neuromuscular and neurodegenerative disorders characterized by expansions of several successive repeated DNA sequences. Currently, more than 50 repeat expansion diseases have been described. These disorders in
Externí odkaz:
https://doaj.org/article/9988c958d61541f3bdb80da928bbde9b
Publikováno v:
Journal of Functional Foods, Vol 94, Iss , Pp 105143- (2022)
Royal jelly (RJ) is one of the most valued natural products and is considered beneficial to human health, mainly due to its many biological and pharmacological properties. 10-Hydroxy-2-decenoic acid (10H2DA), also known as queen bee acid (QBA), is ex
Externí odkaz:
https://doaj.org/article/bbe94f09bb2b454588892d3a7fad439c
Autor:
Yaiza Corral Nieto, Sokhna M. S. Yakhine-Diop, Paula Moreno-Cruz, Laura Manrique García, Amanda Gabrielly Pereira, José A. Morales-García, Mireia Niso-Santano, Rosa A. González-Polo, Elisabet Uribe-Carretero, Sylvère Durand, Maria Chiara Maiuri, Marta Paredes-Barquero, Eva Alegre-Cortés, Saray Canales-Cortés, Adolfo López de Munain, Jordi Pérez-Tur, Ana Pérez-Castillo, Guido Kroemer, José M. Fuentes, José M. Bravo-San Pedro
Publikováno v:
Cells, Vol 12, Iss 5, p 806 (2023)
The identification of Parkinson’s disease (PD) biomarkers has become a main goal for the diagnosis of this neurodegenerative disorder. PD has not only been intrinsically related to neurological problems, but also to a series of alterations in perip
Externí odkaz:
https://doaj.org/article/917e21376071483687b2b7925531f170
Autor:
Francisco A. Sánchez-Crespo, María Teresa Gómez-Villarino, Eutiquio Gallego, José M. Fuentes, Ana I. García, Francisco Ayuga
Publikováno v:
Land, Vol 12, Iss 2, p 408 (2023)
Agricultural production, the main pillar of food security, is highly dependent on soil quality, and threatened by erosion processes that degrade soil quality. This article is part of a research to verify the usefulness of differential interferometric
Externí odkaz:
https://doaj.org/article/f81bad3e3e05493a9e4171fa131d1bf6
Autor:
Eva Alegre-Cortés, Alberto Giménez-Bejarano, Elisabet Uribe-Carretero, Marta Paredes-Barquero, André R. A. Marques, Mafalda Lopes-da-Silva, Otília V. Vieira, Saray Canales-Cortés, Pedro J. Camello, Guadalupe Martínez-Chacón, Ana Aiastui, Roberto Fernández-Torrón, Adolfo López de Munain, Patricia Gomez-Suaga, Mireia Niso-Santano, Rosa A. González-Polo, José M. Fuentes, Sokhna M. S. Yakhine-Diop
Publikováno v:
Cells, Vol 11, Iss 19, p 3018 (2022)
Myotonic dystrophy type 1 (DM1) is an autosomal dominant disease caused by a CTG repeat expansion in the 3′ untranslated region of the dystrophia myotonica protein kinase gene. AKT dephosphorylation and autophagy are associated with DM1. Autophagy
Externí odkaz:
https://doaj.org/article/63ec18c48d0044c082b29aaa2f385fd7
Autor:
Elisabet Uribe-Carretero, Guadalupe Martinez-Chacón, Sokhna M. S. Yakhine-Diop, Gema Duque-González, Mario Rodríguez-Arribas, Eva Alegre-Cortés, Marta Paredes-Barquero, Saray Canales-Cortés, Elisa Pizarro-Estrella, Antonio Cuadrado, Rosa Ana González-Polo, José M. Fuentes, Mireia Niso-Santano
Publikováno v:
Antioxidants, Vol 11, Iss 7, p 1398 (2022)
KEAP1 is a cytoplasmic protein that functions as an adaptor for the Cullin-3-based ubiquitin E3 ligase system, which regulates the degradation of many proteins, including NFE2L2/NRF2 and p62/SQSTM1. Loss of KEAP1 leads to an accumulation of protein u
Externí odkaz:
https://doaj.org/article/c5c362062c1b42fbbd0a0832c1eaaf6f