Zobrazeno 1 - 10
of 36
pro vyhledávání: '"José Luis Millan"'
Autor:
Carmen Huesa, Dongxing Zhu, James D. Glover, Mathieu Ferron, Gerard Karsenty, Elspeth M. Milne, José Luis Millan, S. Faisal Ahmed, Colin Farquharson, Nicholas M. Morton, Vicky E. MacRae
Publikováno v:
Disease Models & Mechanisms, Vol 7, Iss 12, Pp 1341-1350 (2014)
The emergence of bone as an endocrine regulator has prompted a re-evaluation of the role of bone mineralization factors in the development of metabolic disease. Ectonucleotide pyrophosphatase/phosphodiesterase-1 (NPP1) controls bone mineralization th
Externí odkaz:
https://doaj.org/article/821736aae2c841c993ce6616c0e748df
Autor:
Konstantinos Damiris, Filippo Romanelli, Alexei Savinov, José Luis Millan, Jes Kuruvilla, Olga V Savinova
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 37
Objective: Atherosclerosis is a leading cause of chronic mesenteric ischemia (CMI), defined as intestinal hypoperfusion resulting from stenosis of mesenteric arteries. Symptoms of CMI range from non-specific abdominal pain and weight loss to aversion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b13724662d3bb1866b62c5786060a49
https://doi.org/10.1161/atvb.37.suppl_1.495
https://doi.org/10.1161/atvb.37.suppl_1.495
Autor:
Saida Mebarek, Rene Buchet, Slawomir Pikula, Agnieszka Strzelecka-Kiliszek, Leyre Brizuela, Giada Corti, Federica Collacchi, Genevieve Anghieri, Andrea Magrini, Pietro Ciancaglini, Jose Luis Millan, Owen Davies, Massimo Bottini
Publikováno v:
Biomolecules, Vol 14, Iss 1, p 42 (2023)
Mineralization-competent cells, including hypertrophic chondrocytes, mature osteoblasts, and osteogenic-differentiated smooth muscle cells secrete media extracellular vesicles (media vesicles) and extracellular vesicles bound to the extracellular mat
Externí odkaz:
https://doaj.org/article/198c8fda4c7242e4a692415ec39e0a01
Autor:
Flavia Amadeu de Oliveira, Fatma F. Mohamed, Yuka Kinoshita, Sonoko Narisawa, Colin Farquharson, Koichi Miyake, Brian L Foster, Jose Luis Millan
Publikováno v:
JBMR Plus, Vol 7, Iss 1, Pp n/a-n/a (2023)
ABSTRACT Hypophosphatasia (HPP), caused by loss‐of‐function mutations in the ALPL gene encoding tissue‐nonspecific alkaline phosphatase (TNAP), is characterized by skeletal and dental hypomineralization that can vary in severity from life‐thr
Externí odkaz:
https://doaj.org/article/513ba8e0b1914747a10e53df0d3557f7
Autor:
Akihiro Hasegawa, Aki Nakamura-Takahashi, Masataka Kasahara, Nana Saso, Sonoko Narisawa, José Luis Millán, Osamu Samura, Haruhiko Sago, Aikou Okamoto, Akihiro Umezawa
Publikováno v:
Regenerative Therapy, Vol 18, Iss , Pp 168-175 (2021)
Hypophosphatasia (HPP) is a congenital skeletal disease. Impairment of bone mineralization and seizures are due to a deficiency of tissue-nonspecific alkaline phosphatase (TNAP). Enzyme replacement therapy (ERT) is available as a highly successful tr
Externí odkaz:
https://doaj.org/article/c9dde3dbb11342f7a7366c05cf01dec6
Autor:
Tae Matsumoto, Koichi Miyake, Noriko Miyake, Osamu Iijima, Kumi Adachi, Sonoko Narisawa, José Luis Millán, Hideo Orimo, Takashi Shimada
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 22, Iss , Pp 330-337 (2021)
Hypophosphatasia (HPP) is an inherited skeletal disease characterized by defective bone and tooth mineralization due to a deficiency in tissue-nonspecific alkaline phosphatase (TNALP). Patients with the severe infantile form of HPP may appear normal
Externí odkaz:
https://doaj.org/article/1ff49d3faba441c2809be7d1ef379b22
Autor:
Yubo Wang, Liliana Weremiejczyk, Agnieszka Strzelecka‐Kiliszek, Ofelia Maniti, Ekeveliny Amabile Veschi, Mayte Bolean, Ana Paula Ramos, Layth Ben Trad, David Magne, Joanna Bandorowicz‐Pikula, Slawomir Pikula, Jose Luis Millán, Massimo Bottini, Peter Goekjian, Pietro Ciancaglini, René Buchet, Wei Tao Dou, He Tian, Saïda Mebarek, Xiao P. He, Thierry Granjon
Publikováno v:
Journal of Extracellular Biology, Vol 1, Iss 4, Pp n/a-n/a (2022)
Abstract Matrix vesicles (MVs) are 100–300 nm spherical structures released by mineralization competent cells to initiate formation of apatite, the mineral component in bones. Among proteins present in MVs, annexin A6 (AnxA6) is thought to be ubiqu
Externí odkaz:
https://doaj.org/article/38091a2f976f4cbbbd38445873ba476d
Autor:
Karla J. Suchacki, Nicholas M. Morton, Calvin Vary, Carmen Huesa, Manisha C. Yadav, Benjamin J. Thomas, Sophie Turban, Lutz Bunger, Derek Ball, Martin E. Barrios-Llerena, Anyonya R. Guntur, Zohreh Khavandgar, William P. Cawthorn, Mathieu Ferron, Gérard Karsenty, Monzur Murshed, Clifford J. Rosen, Vicky E. MacRae, Jose Luis Millán, Colin Farquharson
Publikováno v:
BMC Biology, Vol 18, Iss 1, Pp 1-20 (2020)
Abstract Background The classical functions of the skeleton encompass locomotion, protection and mineral homeostasis. However, cell-specific gene deletions in the mouse and human genetic studies have identified the skeleton as a key endocrine regulat
Externí odkaz:
https://doaj.org/article/23dc81b350d5458086f9e23af1515cc1
Autor:
Fatma F. Mohamed, Michael B. Chavez, Flavia Amadeu de Oliveira, Sonoko Narisawa, Colin Farquharson, José Luis Millán, Brian L. Foster
Publikováno v:
Frontiers in Dental Medicine, Vol 3 (2022)
Mineralization of the skeleton occurs by several physicochemical and biochemical processes and mechanisms that facilitate the deposition of hydroxyapatite (HA) in specific areas of the extracellular matrix (ECM). Two key phosphatases, phosphatase, or
Externí odkaz:
https://doaj.org/article/84196a09825f413fb3b91696b14a57c3
Autor:
Ana Paula Ramos, Heitor Gobbi Sebinelli, Pietro Ciancaglini, Nicola Rosato, Saida Mebarek, Rene Buchet, José Luis Millán, Massimo Bottini
Publikováno v:
Journal of Extracellular Biology, Vol 1, Iss 1, Pp n/a-n/a (2022)
Abstract Extracellular vesicles (EVs) are lipid bilayer‐enclosed nanosized particles released by all cell types during physiological as well as pathophysiological processes to carry out diverse biological functions, including acting as sources of c
Externí odkaz:
https://doaj.org/article/4234af942d5e40b89215249ceebb448e