Zobrazeno 1 - 10
of 25
pro vyhledávání: '"José L. Ravelo"'
Publikováno v:
Journal of Organometallic Chemistry. 691:5326-5335
A methodology for accessing enantiomerically enriched carbocyclic systems fused to γ-lactones is described. Key steps are the stereoselective synthesis of highly substituted γ-lactones and ring-closing metathesis of the suitable ramifications. The
Publikováno v:
Synlett. 2001:0345-0348
Autor:
Carmen M. Rodríguez, José L. Ravelo, Leticia G. Leon, José M. Padrón, Víctor S. Martín, Rubén P. Machín
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 18:5171-5173
A set of γ-lactones α,β-fused and β,γ-fused to carbocycles have been synthesized and evaluated for their in vitro antiproliferative activities using the human cancer cell lines SW1573 (lung), T-47D (breast) and WiDr (colon). The compounds are ob
Publikováno v:
Tetrahedron Letters. 37:2869-2872
A two-directional approach converting acetals to O-linked oxacycles, by way of intramolecular allyl tin-acetal condensation, is described.
Publikováno v:
Organic Letters. 6:4787-4789
The stereoselective alkylation of α-(phenylsulfonyl)-β-[(methoxycarbonyl)methyl]-γ-lactones obtained by the base-induced cyclization of enantiomerically enriched α-[(phenylthio)acyl]-α,β-unsaturated esters and ring-closing olefin metathesis (RC
Publikováno v:
Chemical Reviews. 95:1953-1980
Publikováno v:
Journal of the American Chemical Society. 108(24)
The primary objective in this investigation was to develop a general method to achieve a significant amount of asymmetric induction in the bromonium initiated intramolecular carbocyclization reaction. This goal has been achieved by generation of exoc
Autor:
Ricardo Perez, Jose A. Vera, Maria Teresa Diaz, José L. Ravelo, Eleuterio Álvarez, Alicia Regueiro, Julio D. Martín, Dácil Zurita
Publikováno v:
The Journal of Organic Chemistry. 59:2848-2876
A successful design for the construction of trans-fused medium-size cy- clic ethers is described. The key features of the synthesis are as fol- lows: (i) intramolecular oxirane ring expansion in cycloalkenes to give bridged oxabicyclic systems and (i
Autor:
José L. Ravelo, Jose A. Vera, Julio D. Martín, Dácil Zurita, Eleuterio Álvarez, Alicia Regueiro, Ricardo Perez, Maria Teresa Diaz
Publikováno v:
ChemInform. 25
A successful design for the construction of trans-fused medium-size cy- clic ethers is described. The key features of the synthesis are as fol- lows: (i) intramolecular oxirane ring expansion in cycloalkenes to give bridged oxabicyclic systems and (i
Publikováno v:
Tetrahedron Letters. 33:3389-3392
The synthesis of a conveniently functionalised oxocene-oxane-oxepane framework was achieved by two simultaneous one-carbon homologations followed by a one-pot double carbon-carbon bond-forming strategy.