Zobrazeno 1 - 10
of 46
pro vyhledávání: '"José L. García-Navío"'
Publikováno v:
Tetrahedron Letters. 41:9819-9823
4-Substituted 3,4-dihydro-1H-2,1,3-benzothiadiazine 2,2-dioxides 11 have been efficiently prepared in two steps from the suphamide 9 by condensation of anion II, derived from 9 by metal–halogen exchange, with aromatic and aliphatic aldehydes and cy
Autor:
Andrés Molina, Juan J. Vaquero, Julio Alvarez-Builla, José L. García-Navío, M. M. Rodrigo, Beatriz de Pascual-Teresa, and Federico Gago
Publikováno v:
The Journal of Organic Chemistry. 64:3907-3915
A new class of DNA intercalators based on the 8H-pyridazino[1‘,6‘:1,2]pyrido[4,3-b]indol-5-inium system in which the cationic nature of the chromophore is provided by a brigdehead quaternary nitrogen has been obtained. These cations along with 10
Publikováno v:
Tetrahedron. 53:12755-12764
The Suzuki-type cross-coupling reaction of 6-substituted 1-benzyl-2-iodo-1H-benzimidazoles with aryl boronic acids provided an efficient synthesis of the corresponding 2-ary-1H-benzimidazoles. The reaction was catalyzed by palladium(0) under differen
Autor:
Jorge G. Siro, M. Melia Rodrigo, Beatriz de Pascual-Teresa, and Manuel Pastor, Juan J. Vaquero, Joaquín Pastor, Julio Alvarez-Builla, José L. García-Navío, Federico Gago
Publikováno v:
The Journal of Organic Chemistry. 62:5476-5483
The synthesis of new pyrido[1,2-a]- and pyridazino[1,6-a]benzimidazolium salts by basic condensation of 1,3-disubstituted 2-alkylbenzimidazolium salts and 1,2-diketones and subsequent chemical transformations is described. The DNA-binding properties
Autor:
Sénida Cueto, Juan A. Vega, José L. García-Navío, Andrés Ramos, Jesús Ezquerra, Juan J. Vaquero, Julio Alvarez-Builla
Publikováno v:
Tetrahedron Letters. 37:6413-6416
A diastereoselective one-pot synthesis of the trans- and cis-3-hydroxy-2-(4-methoxyphenyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one nucleus, a key intermediate in the preparation of the calcium channel blocker Diltiazem, is carried out under microwav
Autor:
María I. Castellote, José L. García-Navío, Obis Castaño, Jose L. Andres, Jose M. Minguez, Julio Alvarez-Builla, Juan J. Vaquero
Publikováno v:
The Journal of Organic Chemistry. 61:4655-4665
A new synthesis of the pyrrolo[1,2-a]pyrazine system from pyrrole is described. In light of the ab initio calculations carried out on this heterocyclic system some of its basic chemistry was investigated and included electrophilic substitution, addit
Autor:
and María M. Rodrigo, Juan J. Vaquero, José L. García-Navío, Federico Gago, Andrés Molina, Julio Alvarez-Builla, Milagros Ballesteros, Beatriz de Pascual-Teresa
Publikováno v:
The Journal of Organic Chemistry. 61:5587-5599
The 5H-pyrido[4,3-b]indole, 11H-indolo[3,2-c]quinoline, 5H-benzo[f]pyrido[4,3-b]indole, and 13H-benz[5,6]indolo[3,2-c]quinoline heteroaromatic nuclei have been synthesized by the Graebe−Ullmann method by classical heating or under microwave irradia
Autor:
José L. García-Navío, Obis Castaño, Jose L. Andres, Jorge G. Siro, Julio Alvarez-Builla, Juan J. Vaquero, Inmaculada Santiesteban
Publikováno v:
The Journal of Organic Chemistry. 60:5667-5672
Autor:
José L. García-Navío, M. L. Izquierdo, Pilar Gómez-Sal, Julio Alvarez-Builla, Federico Gago, Mariano Fajardo, Rosa Carceller
Publikováno v:
e_Buah Biblioteca Digital Universidad de Alcalá
instname
instname
Several azinium-N-(2′-azinyl)aminides are reported. The structure of pyridinium-N-(2′-pyridyl)aminide has been studied, both in solution and in crystalline state, and results have been compared. In non-polar solvents, the aminides present a plana
Publikováno v:
Tetrahedron Letters. 43:8025-8027
An unexpected bromocyclocarbamoylation of o -allylic N -BOC-anilines has been observed producing 2-oxo-3,1-benzoxazocine derivatives through an 8- endo - trig process, which on heating ring-transformed into a [6.5.5] tricyclic fused oxazolidinone com