Výsledky vyhledávání - "José L. De la Vega-Beltrán"

Cdc42 localized in the CatSper signaling complex regulates cAMP‐dependent pathways in mouse sperm

Autor: Dario Krapf, Alberto Darszon, Mariano G. Buffone, Guillermina Maria Luque, Cintia Stival, Xinran Xu, Nicolas Gilio, Gerardo Orta, Pablo E. Visconti, Maria Gracia Gervasi, Ana Romarowski, Tomás Dalotto-Moreno, José L. De la Vega-Beltrán, Diego Krapf

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

Sperm acquire the ability to fertilize in a process called capacitation and undergo hyperactivation, a change in the motility pattern, which depends on Ca2+ transport by CatSper channels. CatSper is essential for fertilization and it is subjected to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9577e4e2098cce21325d97110964340d
Wiley Online Library

Zobrazit plný text záznamu

Starvation induces an increase in intracellular calcium and potentiates the progesterone-induced mouse sperm acrosome reaction

Autor: Claudia Sánchez-Cárdenas, Ana Romarowski, Gerardo Orta, José L. De la Vega-Beltrán, Arturo Hernández-Cruz, Alberto Darszon, Pablo E. Visconti, David Martin-Hidalgo

Publikováno v: FASEB J

We have recently reported two different methodologies that improve sperm functionality. The first method involved transient exposure to the Ca(2+) ionophore A(23187), the second required sperm incubation in the absence of energy nutrients (starvation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43ecc83933f7da8531831e19a758f356
https://pubmed.ncbi.nlm.nih.gov/33742713

Zobrazit plný text záznamu

Akademický článek

Ion permeabilities in mouse sperm reveal an external trigger for SLO3-dependent hyperpolarization.

Autor: Julio C Chávez, José L de la Vega-Beltrán, Jessica Escoffier, Pablo E Visconti, Claudia L Treviño, Alberto Darszon, Lawrence Salkoff, Celia M Santi

Publikováno v: PLoS ONE, Vol 8, Iss 4, p e60578 (2013)

Unlike most cells of the body which function in an ionic environment controlled within narrow limits, spermatozoa must function in a less controlled external environment. In order to better understand how sperm control their membrane potential in dif

Externí odkaz: https://doaj.org/article/a1cfa35ef96d4e71ae1b54a6f8e861c8

Zobrazit plný text záznamu

Cdc42 activity is essential for the interplay between cAMP/PKA pathway and CatSper function

Autor: Dario Krapf, Maria Gracia Gervasi, Xinran Xu, Diego Krapf, José L. De la Vega-Beltrán, Nicolas Gilio, Pablo E. Visconti, Cintia Stival, Mariano G. Buffone, Guillermina Maria Luque, Gerardo Orta, Alberto Darszon, Ana Romarowski, Tomás Dalotto-Moreno

Sperm acquire the ability to fertilize in a process called capacitation and undergo hyperactivation, a change in the motility pattern, which depends on Ca2+transport by CatSper channels. CatSper is essential for fertilization and it is subjected to a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::73dadc6ef891250d0eae4b5ebf111210
https://doi.org/10.1101/2020.08.24.264739

Zobrazit plný text záznamu

Acrosomal alkalization triggers Ca2+release and acrosome reaction in mammalian spermatozoa

Autor: Alberto Darszon, Claudia L. Treviño, Takuya Nishigaki, Paulina Torres, Omar José, Julio C. Chávez, José L. De la Vega-Beltrán

Publikováno v: Journal of Cellular Physiology. 233:4735-4747

The sperm acrosome reaction (AR), an essential event for mammalian fertilization, involves Ca2+ permeability changes leading to exocytosis of the acrosomal vesicle. The acrosome, an intracellular Ca2+ store whose luminal pH is acidic, contains hydrol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b04d79c98702442f7fa0f4a4c6f0d908
https://doi.org/10.1002/jcp.26262

Zobrazit plný text záznamu

Role of human Hv1 channels in sperm capacitation and white blood cell respiratory burst established by a designed peptide inhibitor

Autor: Rodolfo J. Arias, Martin Alejandro Pavarotti, Gerardo A. De Blas, Qufei Li, Alberto Darszon, Eduardo Perozo, Hui Dai, Gerardo Orta, Kelleigh Kennedy, Ruiming Zhao, Luis S. Mayorga, Steve A.N. Goldstein, José L. De la Vega-Beltrán

Publikováno v: Proceedings of the National Academy of Sciences. 115

Using a de novo peptide inhibitor, Corza6 (C6), we demonstrate that the human voltage-gated proton channel (hHv1) is the main pathway for H+ efflux that allows capacitation in sperm and permits sustained reactive oxygen species (ROS) production in wh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85ca92a9fa7f5e044ef3a9f65d44221f
https://doi.org/10.1073/pnas.1816189115

Zobrazit plný text záznamu

Disruption of protein kinase A localization induces acrosomal exocytosis in capacitated mouse sperm

Autor: Maria Gracia Gervasi, Xinran Xu, Mariano G. Buffone, Dario Krapf, Nicolás Torres, Cintia Stival, Guillermina Maria Luque, José L. De la Vega-Beltrán, Diego Krapf, Carolina Baro Graf, Alberto Darszon, Pablo E. Visconti, Carla Ritagliati

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

Protein kinase A (PKA) is a broad-spectrum Ser/Thr kinase involved in the regulation of several cellular activities. Thus, its precise activation relies on being localized at specific subcellular places known as discrete PKA signalosomes. A-Kinase an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aae3dfd7becd386b6999f40cad04da3f
https://www.ncbi.nlm.nih.gov/pubmed/29700114

Zobrazit plný text záznamu

CatSper channels are regulated by protein kinase A

Autor: Alberto Darszon, Celia M. Santi, Gerardo Orta, David Martin-Hidalgo, Pablo E. Visconti, José L. De la Vega-Beltrán

Publikováno v: The Journal of biological chemistry. 293(43)

Mammalian sperm must undergo capacitation as a preparation for entering into hyperactivated motility, undergoing the acrosome reaction, and acquiring fertilizing ability. One of the initial capacitation events occurs when sperm encounter an elevated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d8e2dd25c5f93e4b6094265e31183cb
https://pubmed.ncbi.nlm.nih.gov/30213858

Zobrazit plný text záznamu

Acrosomal alkalization triggers Ca

Autor: Julio C, Chávez, José L, De la Vega-Beltrán, Omar, José, Paulina, Torres, Takuya, Nishigaki, Claudia L, Treviño, Alberto, Darszon

Publikováno v: Journal of cellular physiology. 233(6)

The sperm acrosome reaction (AR), an essential event for mammalian fertilization, involves Ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d0e293e0fd9e1245730c2a6c3588619f
https://pubmed.ncbi.nlm.nih.gov/29135027

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání