Výsledky vyhledávání - "José L. Barra"

Novel intein-based self-cleaving affinity tag for recombinant protein production in Escherichia coli

Autor: José L. Barra, Paula Vaccarello, Elisa M.E. Correa, Marilla Amaranto, Agustina Godino

Publikováno v: Journal of Biotechnology. 332:126-134

We evaluated several intein-based self-cleaving affinity tags for expression and single-step affinity chromatography purification of recombinant proteins produced in Escherichia coli. We used human growth hormone (hGH) as target protein that contains

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0451c116d31d68d87efab91f36c1a1cd
https://doi.org/10.1016/j.jbiotec.2021.04.003

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Human α-Galactosidase A Mutants: Priceless Tools to Develop Novel Therapies for Fabry Disease

Autor: Rosa Mendoza, José L. Barra, Andrea Modrego, Marilla Amaranto, Agustina Godino, José Luis Corchero

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 6518, p 6518 (2021)
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona

Fabry disease (FD) is a lysosomal storage disease caused by mutations in the gene for the α-galactosidase A (GLA) enzyme. The absence of the enzyme or its activity results in the accumulation of glycosphingolipids, mainly globotriaosylceramide (Gb3)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ed35bb18092f450abdca200f8b52aa1
http://europepmc.org/articles/PMC8234732

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Akademický článek

Analysis of the interaction interfaces of the N-terminal domain from Pseudomonas aeruginosa MutL.

Autor: Virginia Miguel, Elisa M E Correa, Luisina De Tullio, José L Barra, Carlos E Argaraña, Marcos A Villarreal

Publikováno v: PLoS ONE, Vol 8, Iss 7, p e69907 (2013)

Mismatch Repair System corrects mutations arising from DNA replication that escape from DNA polymerase proofreading activity. This system consists of three main proteins, MutS-L-H, responsible for lesion recognition and repair. MutL is a member of GH

Externí odkaz: https://doaj.org/article/f8b1516803034a198e53f25929971d01

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DNA repair, NFKβ, and TP53 polymorphisms associated with potentially malignant disorders and oral squamous cell carcinoma in Argentine patients

Autor: Julieta Don, Dante Gustavo Secchi, Ana María Zarate, Andres Carrica, José L. Barra, Mabel Brunotto, María Fernanda Galíndez

Publikováno v: Oral surgery, oral medicine, oral pathology and oral radiology. 131(3)

Objective An important strategy in cancer prevention is to identify individual susceptibilities for cancer development through the genomic profile. Developing countries such as Argentina have no data on genetic composition. The aim of this study was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0bdd89181ee1ce7a9de614c8962d528
https://pubmed.ncbi.nlm.nih.gov/33309268

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Advantages and Disadvantages of His-Tagged Beta-Galactosidase

Autor: Sandra S. Flores, Pedro D. Clop, José L. Barra, Carlos Argaraña, María A. Perillo, Verónica Nolan, Julieta M. Sanchez

β-Galactosidase is one of the most important biotechnological enzyme used in the dairy industry, pharmacology and in molecular biology. In our laboratory we have overexpressed a recombinant β-galactosidase in Escherichia coli (E. coli). This enzyme

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::da980eb7ca48a0e9a8a9b9bb62a03ffe
https://doi.org/10.21203/rs.3.rs-54150/v1

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Akademický článek

Escherichia coli frameshift mutation rate depends on the chromosomal context but not on the GATC content near the mutation site.

Autor: Mariana A Martina, Elisa M E Correa, Carlos E Argaraña, José L Barra

Publikováno v: PLoS ONE, Vol 7, Iss 3, p e33701 (2012)

Different studies have suggested that mutation rate varies at different positions in the genome. In this work we analyzed if the chromosomal context and/or the presence of GATC sites can affect the frameshift mutation rate in the Escherichia coli gen

Externí odkaz: https://doaj.org/article/d527e403b02c40968bb83c4b526e7c1b

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DIAGNOSTIC MODEL OF EARLY STAGE OF ORAL CANCER BASED ON SINGLE NUCLEOTIDE POLYMORPHISMS

Autor: María Fernanda Galíndez Costa, René Panico, Dante Gustavo Secchi, Mabel Brunotto, Ignacio Gonzalez Segura, José L. Barra, Victoriano Andrés Carrica

Publikováno v: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 129:e153-e154

Objective To evaluate genotypic characteristics of patients with oral cancer (OC) in order to develop a statistical risk prediction model for Argentine populations, and to improve their prevention, treatment, and follow-up care. Methods A case-contro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1676e3f3b47fc2ce91f107527bb09725
https://doi.org/10.1016/j.oooo.2019.06.660

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Akademický článek

Medición de incisiones quirúrgicas después de realizar cirugía lumbar con abordaje posterior

Autor: Alejandro Reyes-Sánchez, Joab D. Olivo-Gómez, José L. Barragán-Hermosillo, Juan C. Gómez-Ríos, Luis M. Rosales-Olivarez, Armando Alpízar-Aguirre, Alejandro Miranda-Palestino, Alejandro Domínguez-Soto, Carla L. García-Ramos

Publikováno v: Anales Médicos, Vol 69, Iss 1 (2024)

Antecedentes: Las ventajas de la cirugía mínimamente invasiva debido a las incisiones pequeñas en comparación con la cirugía tradicional están descritas en la literatura, sin embargo, no existe una medida establecida en cuanto al tamaño de la

Externí odkaz: https://doaj.org/article/3b3eb00984aa440a9912b356712ee3f1

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Autor: Victiruano Andres Carrica, Panico Rene, Ana María Zarate, José L. Barra, Galindez Costa María Fernanda, Unamuno Victoria, Irazuzta Graciana

Publikováno v: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 129:e154

Objective To assess carcinogen related CYP1A1 and GSTM1 genetic polymorphisms in oral cancer (OC) and oral potentially malignant disorders (OPMD). Study Design One hundred smokers were studied: OC = 30, OPMD = 45 (leukoplakia and oral lichen planus)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::173ebfbbefed44bdb499de95f0ac3061
https://doi.org/10.1016/j.oooo.2019.06.661

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Study of the TP53 codon 72 polymorphism in oral cancer and oral potentially malignant disorders in Argentine patients

Autor: Julieta Don, Fernanda Galindez Costa, José L. Barra, René Panico, Mabel Brunotto, Dante Gustavo Secchi, Ana María Zarate, Martín Brusa, Andres Carrica

Publikováno v: Tumor Biology, Vol 39 (2017)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

The aim of this work was to evaluate the prevalence of TP53Arg72Pro mutations and their possible relationship with oral carcinoma and oral potentially malignant disorders in Argentine patients. A cross-sectional study was performed on 111 exfoliated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0b3f6990013f5b81b3055c60344b795
https://doaj.org/article/a112e4284fba4af69db291cb4f0b7536

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