PK/PD Analysis by Nonlinear Mixed-Effects Modeling of a Marbofloxacin Dose Regimen for Treatment of Goat Mastitis Produced by Coagulase-Negative Staphylococci

Autor: Augusto Matías Lorenzutti, Juan Pablo Vico, Juan Manuel Serrano-Rodríguez, Martín Alejandro Himelfarb, Manuel Ignacio San Andrés-Larrea, José Julio de Lucas-Burneo, Nicolás Javier Litterio

Publikováno v: Animals, Vol 11, Iss 11, p 3098 (2021)

Coagulase-negative staphylococci are main pathogens that produce goat mastitis. Marbofloxacin is a third-generation fluoroquinolone approved for treat mastitis in animals. The objectives of this study were: (i) to determine the pharmacokinetics of ma

Externí odkaz: https://doaj.org/article/f26c691aecde405aa1c022eb05054097

PK/PD Analysis by Nonlinear Mixed-Effects Modeling of a Marbofloxacin Dose Regimen for Treatment of Goat Mastitis Produced by Coagulase-Negative Staphylococci

Autor: Nicolás Javier Litterio, J. P. Vico, Augusto Matías Lorenzutti, José Julio de Lucas-Burneo, Juan Manuel Serrano-Rodríguez, Manuel Ignacio San Andrés-Larrea, Martín Alejandro Himelfarb

Publikováno v: Animals : an Open Access Journal from MDPI
Animals, Vol 11, Iss 3098, p 3098 (2021)
E-Prints Complutense. Archivo Institucional de la UCM
instname
Animals
Volume 11
Issue 11

Coagulase-negative staphylococci are main pathogens that produce goat mastitis. Marbofloxacin is a third-generation fluoroquinolone approved for treat mastitis in animals. The objectives of this study were: (i) to determine the pharmacokinetics of ma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::969a32418d57c9a2f1e468900268dbc2
https://pubmed.ncbi.nlm.nih.gov/34827830

Evaluation of allometric scaling as a tool for extrapolation of the enrofloxacin dose in American black vultures (Coragyps atratus)

Autor: A. P. Prados, Guillermo Wiemeyer, Manuel Ignacio San Andres, José Julio de Lucas, Samanta Waxman, Laura Torres-Bianchini, Casilda Rodríguez

Publikováno v: American Journal of Veterinary Research. 80:727-735

OBJECTIVE To determine the pharmacokinetics of enrofloxacin after IV administration in American black vultures (Coragyps atratus), to compare clearance of enrofloxacin in American black vultures with clearance of this fluoroquinolone in other avian s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fd26cca4ad0348a5eb4662f8b417ab3b
https://doi.org/10.2460/ajvr.80.8.727

Pharmacokinetics of doxycycline after oral administration of multiple doses in dogs

Autor: Casilda Rodríguez, Ángel Sainz, Manuel Ignacio San Andres, Alejandra Villaescusa, José Julio de Lucas, María Dolores San Andrés, Fernando Rodríguez-Franco, Mercedes García-Sancho

Publikováno v: Journal of veterinary pharmacology and therapeuticsREFERENCES. 44(3)

The aim of this study was to determine the pharmacokinetic parameters of doxycycline in dogs and assess the efficacy of an oral drug dosage regimen of 10 mg/kg daily for 28 days through Pharmacokinetic/Pharmacodynamic (PK/PD) target analysis based on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::380c6038d796b519522234baa1508cb3
https://pubmed.ncbi.nlm.nih.gov/33991120

Pharmacokinetic/pharmacodynamic analysis by Monte Carlo simulation of cefquinome in llamas, following intravenous, intramuscular and subcutaneous administration in serum and tissue cage fluid

Autor: Nicolás Javier Litterio, José Julio de Lucas, Augusto Matías Lorenzutti, Manuel Ignacio San Andres, Martín Alejandro Himelfarb, María Soledad Aguilar-Sola, María del Pilar Zarazaga, Sonia Rubio-Langre

Publikováno v: Small Ruminant Research. 149:134-140

The objective of this study was to determine the pharmacokinetic behavior of cefquinome (CFQ) in serum and tissue cage fluid (TCF) in llamas, after intravenous (IV), intramuscular (IM) and subcutaneous (SC) administration of 2 mg/kg. Two tissue cages

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0548282d61fface3acb0291b415af599
https://doi.org/10.1016/j.smallrumres.2017.02.004