Zobrazeno 1 - 5
of 5
pro vyhledávání: '"José I. Pueyo"'
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Translation of 100 to 300 micropeptides from small ORFs within lncRNA was detected by Ribosomal Profiling in Drosophila embryos. These translated small ORFs showed natural selection conserving micropeptide sequence and function.
Externí odkaz:
https://doaj.org/article/5a40e3f904794cdcad53ae9b2f86edeb
Autor:
Jose I. Pueyo, Jorge Salazar, Carolina Grincho, Jimena Berni, Benjamin P. Towler, Sarah F. Newbury
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Recent advances in proteogenomic techniques and bioinformatic pipelines have permitted the detection of thousands of translated small Open Reading Frames (smORFs), which contain less than 100 codons, in eukaryotic genomes. Hundreds of these actively
Externí odkaz:
https://doaj.org/article/be316e1f25814526bb4e696953c8b099
Autor:
Emile G. Magny, Ana Isabel Platero, Sarah A. Bishop, Jose I. Pueyo, Daniel Aguilar-Hidalgo, Juan Pablo Couso
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Short open reading frames (smORFs) of less than 100 codons exist in the thousands in metazoan genomes, mostly with yet unknown functions. Here the authors show how a smORF conserved from flies to vertebrates produces a secreted peptide that enhances
Externí odkaz:
https://doaj.org/article/7f17f13f747943899fbf04ba7e53500e
Publikováno v:
Development (Cambridge, England). 127(24)
Proximal-distal leg development in Drosophila involves a battery of genes expressed and required in specific proximal-distal (PD) domains of the appendage. Here we report the characterisation of a new gene of this type, dlim1, a member of the Lhx fam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ce689d8dde6113b07706157cd9df24b
https://pubmed.ncbi.nlm.nih.gov/11076760
https://pubmed.ncbi.nlm.nih.gov/11076760
Autor:
José I Pueyo, Emile G Magny, Christopher J Sampson, Unum Amin, Iwan R Evans, Sarah A Bishop, Juan P Couso
Publikováno v:
PLoS Biology, Vol 14, Iss 3, p e1002395 (2016)
Translation of hundreds of small ORFs (smORFs) of less than 100 amino acids has recently been revealed in vertebrates and Drosophila. Some of these peptides have essential and conserved cellular functions. In Drosophila, we have predicted a particula
Externí odkaz:
https://doaj.org/article/8f8e305b64d54c66965a1343bd052418