Zobrazeno 1 - 10
of 34
pro vyhledávání: '"José I. Piruat"'
Autor:
Alicia Báez, Beatriz Martín-Antonio, José I. Piruat, Concepción Prats, Isabel Álvarez-Laderas, M. Victoria Barbado, Magdalena Carmona, Álvaro Urbano-Ispizua, Jose Antonio Pérez-Simón
Publikováno v:
Haematologica, Vol 99, Iss 2 (2014)
Granulocyte colony-stimulating factor is the most commonly used cytokine for the mobilization of hematopoietic progenitor cells from healthy donors for allogeneic stem cell transplantation. Although the administration of this cytokine is considered s
Externí odkaz:
https://doaj.org/article/ebf53c03abaa4002b741737e7c0a4270
Autor:
Africa Millán-Uclés, Blanca Díaz-Castro, Paula García-Flores, Alicia Báez, José Antonio Pérez-Simón, José López-Barneo, José I Piruat
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85528 (2014)
Mutations in mitochondrial complex II (MCII; succinate dehydrogenase, Sdh) genes cause familiar pheochromocytoma/paraganglioma tumors. Several mechanisms have been proposed to account for Sdh-mutation-induced tumorigenesis, the most accepted of which
Externí odkaz:
https://doaj.org/article/bdebaca2f681426d9c2df54d9c73c9b3
Autor:
Teresa L. Ramos, Marina Sánchez-Hidalgo, Mayte Medrano, José I. Piruat, Catalina Alarcón-de-la-Lastra, José A. Pérez-Simón, Francisco J. Hidalgo, María Victoria Barbado, Rosario Zamora, Rocío Caracuel-García, Isabel Álvarez-Laderas, Teresa Caballero-Velázquez
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
idUS. Depósito de Investigación de la Universidad de Sevilla
9 Figuras
Polyphenols are a group of chemical substances found in plants, with immunomodulatory, antiproliferative, and anti-inflammatory properties that might be useful in the prophylaxis and treatment of graft-versus-host disease (GVHD). Polyp
Polyphenols are a group of chemical substances found in plants, with immunomodulatory, antiproliferative, and anti-inflammatory properties that might be useful in the prophylaxis and treatment of graft-versus-host disease (GVHD). Polyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92a484c373a38908abdb9d95b1654414
http://hdl.handle.net/10261/200939
http://hdl.handle.net/10261/200939
Autor:
María José Castro, José A. Pérez-Simón, Teresa Caballero-Velázquez, José I. Piruat, Iván V. Rosado, Paula Moreno-Gordillo, Clara B. García-Calderón, Jose Antonio Bejarano-García, Isabel Tinoco-Gago
Publikováno v:
Cell Death & Differentiation. 25:1967-1979
Metabolically reactive formaldehyde is a genotoxin and a carcinogen. Mice lacking the main formaldehyde-detoxifying gene Adh5 combined with the loss of the Fanconi anemia (FA) DNA repair pathway rapidly succumbed to bone marrow failure (BMF) primaril
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4515c70872cbb6fb082c383b264f9f7
https://doi.org/10.1038/s41418-018-0089-4
https://doi.org/10.1038/s41418-018-0089-4
Autor:
Iván V. Rosado, José Antonio Pérez-Simón, Teresa Caballero-Velázquez, Pedro González-Naranjo, M. Victoria Barbado, Luis Ignacio Sánchez-Abarca, Mayte Medrano, Jesús Martín-Sánchez, Estefania Garcia-Guerrero, Isabel Álvarez-Laderas, Juan A. Páez, Nuria E. Campillo, José I. Piruat
Publikováno v:
International Journal of Cancer. 140:674-685
Although hematopoietic and immune system show high levels of the cannabinoid receptor CB2, the potential effect of cannabinoids on hematologic malignancies has been poorly determined. Here we have investigated their anti-tumor effect in multiple myel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a6ce96d264a8e795b83cc4bcc813eb3
https://doi.org/10.1002/ijc.30483
https://doi.org/10.1002/ijc.30483
Autor:
Ricardo Pardal, Verónica Sobrino, Blanca Diaz-Castro, José López-Barneo, José I. Piruat, Rocío Durán, Paula García-Flores
Publikováno v:
EMBO reports. 16:1511-1519
Mitochondria play a central role in stem cell homeostasis. Reversible switching between aerobic and anaerobic metabolism is critical for stem cell quiescence, multipotency, and differentiation, as well as for cell reprogramming. However, the effect o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a034f20f961c71721e90003e50613e2
https://doi.org/10.15252/embr.201540982
https://doi.org/10.15252/embr.201540982
Autor:
Xiaoli Zhang, Amruta Ashtekar, Sissy M. Jhiang, José I. Piruat, Krista M. D. La Perle, Danielle Huk, Lawrence S. Kirschner, Alexa Magner, José López-Barneo
Mutations in genes encoding enzymes in the tricarboxylic acid cycle (TCA, also known as the Krebs cycle) have been implicated as causative genetic lesions in a number of human cancers, including renal cell cancers, glioblastomas and pheochromocytomas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86a5f669e611714d0b15b5ce8505b16c
https://europepmc.org/articles/PMC5650926/
https://europepmc.org/articles/PMC5650926/
Autor:
Bartolomé Scola, Milagros Balbín, Aurora Astudillo, Anna Merlo, Raquel del Toro, Ana S. Pitiot, Nuria Valdés, José I. Piruat, Inés Sáenz-de-Santa-María, Simón Méndez-Ferrer, Cristóbal Bernardo-Castiñeira, Carlos Suárez, María-Dolores Chiara
Publikováno v:
Scopus
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
Oncotarget
RUO: Repositorio Institucional de la Universidad de Oviedo
Universidad de Oviedo (UNIOVI)
Digital.CSIC. Repositorio Institucional del CSIC
Repisalud
Instituto de Salud Carlos III (ISCIII)
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
Oncotarget
RUO: Repositorio Institucional de la Universidad de Oviedo
Universidad de Oviedo (UNIOVI)
Digital.CSIC. Repositorio Institucional del CSIC
Repisalud
Instituto de Salud Carlos III (ISCIII)
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
The hypoxia-inducible factor 1α (HIF-1α) and its microRNA target, miR-210, are candidate tumor-drivers of metabolic reprogramming in cancer. Neuroendocrine neoplasms such as paragangliomas (PGLs) are particularly appealing for understanding the can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d93c72ffe6eff5872ebb199445500026
http://hdl.handle.net/10651/42408
http://hdl.handle.net/10651/42408
Autor:
África Millán-Uclés, Alicia Báez, Teresa Caballero-Velázquez, José I. Piruat, Estefania Garcia-Guerrero, Luis Ignacio Sánchez-Abarca, Mayte Medrano, José Antonio Pérez-Simón, María Victoria Barbado, Isabel Álvarez-Laderas
Publikováno v:
Immunology. 144:395-404
Memory B cells (MBCs) have a long lifespan compared with naive B cells (NBCs), remaining viable for years. This could predispose them to suffer misbalances in the gene expression pattern in the long term, which might be involved in the development of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef16d71a7730b98d7da72849f068dd0f
https://doi.org/10.1111/imm.12381
https://doi.org/10.1111/imm.12381
Autor:
Iván V. Rosado, Teresa Caballero-Velázquez, José I. Piruat, José A. Pérez-Simón, María José Durán-Galván, Jose Antonio Bejarano-García, África Millán-Uclés, Luis Ignacio Sánchez-Abarca
Publikováno v:
idUS: Depósito de Investigación de la Universidad de Sevilla
Universidad de Sevilla (US)
Cell Death & Disease
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
Universidad de Sevilla (US)
Cell Death & Disease
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
It is established that hematopoietic stem cells (HSC) in the hypoxic bone marrow have adapted their metabolism to oxygen-limiting conditions. This adaptation includes suppression of mitochondrial activity, induction of anerobic glycolysis, and activa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f2a3c8e3acd3c8df7fcf9db455f434a