Výsledky vyhledávání - "José Hernández-Jiménez"

Akademický článek

Use of subcutaneous tocilizumab to prepare intravenous solutions for COVID-19 emergency shortage: Comparative analytical study of physicochemical quality attributes

Autor: Natalia Navas, Jesús Hermosilla, Anabel Torrente-López, José Hernández-Jiménez, Jose Cabeza, Raquel Pérez-Robles, Antonio Salmerón-García

Publikováno v: Journal of Pharmaceutical Analysis, Vol 10, Iss 6, Pp 532-545 (2020)

COVID-19, a disease caused by the novel coronavirus SARS-CoV-2, has produced a serious emergency for global public health, placing enormous stress on national health systems in many countries. Several studies suggest that cytokine storms (interleukin

Externí odkaz: https://doaj.org/article/9558f070220e4a558a4a9e25c08f46dc

Zobrazit plný text záznamu

Akademický článek

Daños para la salud tras exposición laboral a nanopartículas

Autor: Lydia Gutiérrez González, María José Hernández Jiménez, Leonor Molina Borchert

Publikováno v: Medicina y Seguridad del Trabajo, Vol 59, Iss 231, Pp 276-296 (2013)

Introducción: La exposición a nanopartículas ha aumentado en los últimos años de forma significativa debido a su utilización en muchos sectores industriales y en el ámbito doméstico. Se prevé que el empleo en la industria de la nanotecnolog�

Externí odkaz: https://doaj.org/article/943b7e5efcb3468c9323eade2543adee

Zobrazit plný text záznamu

3PC-065 Impact of light stress on the isoform profile of nivolumab (Opdivo) in opened vials estimated by (RP)UHPLC-UV-(HESI/Orbitrap)-MS

Autor: J Hermosilla-Fernández, Anabel Torrente-López, Natalia Navas, José Cabeza, José Hernández-Jiménez, Antonio Salmerón-García

Publikováno v: Section 2: Selection, procurement and distribution.

Background and importance Nivolumab (Opdivo) is a human IgG4 monoclonal antibody from the group of immunomodulators which bind to the programmed death receptor 1 (PD-1). As a complex protein, physical aggregation and chemical degradation can occur th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::18585faeb4e0442013e2adf05917504c
https://doi.org/10.1136/ejhpharm-2021-eahpconf.40

Zobrazit plný text záznamu

3PC-062 Impact of the preparation of 1.0 mg/mL nivolumab clinical solution on the particulates (aggregation) measured by dynamic light scattering: NaCl and glucose concentration and agitation effect

Autor: J Hermosilla Fernández, D Muñoz-Prieto, Natalia Navas, José Hernández-Jiménez, Antonio Salmerón-García, Anabel Torrente-López, José Cabeza

Publikováno v: Section 2: Selection, procurement and distribution.

Background and importance Nivolumab (Opdivo) is a human immunoglobulin G4 monoclonal antibody that binds to programmed death receptor 1 (PD-1) and blocks its interaction with PD-L1 and PD-L2. As a complex protein, routine handling or unintentional mi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1ac4012a6882cad61dba6400db6b1ea3
https://doi.org/10.1136/ejhpharm-2021-eahpconf.37

Zobrazit plný text záznamu

Use of subcutaneous tocilizumab to prepare intravenous solutions for COVID-19 emergency shortage: Comparative analytical study of physicochemical quality attributes

Autor: Antonio Salmerón-García, José Hernández-Jiménez, Natalia Navas, Anabel Torrente-López, Jesús Hermosilla, José Cabeza, Raquel Pérez-Robles

Publikováno v: Digibug: Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)
Digibug. Repositorio Institucional de la Universidad de Granada
instname
Journal of Pharmaceutical Analysis, Vol 10, Iss 6, Pp 532-545 (2020)
Journal of Pharmaceutical Analysis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b6e38237dd5e7a0655e3dc60a47ea57
https://hdl.handle.net/10668/3505

Zobrazit plný text záznamu

Study of aggregation in therapeutic monoclonal antibodies subjected to stress and long-term stability tests by analyzing size exclusion liquid chromatographic profiles

Autor: José Cabeza, Natalia Navas, Antonio Martínez-Ortega, Jose Prados, Raúl Ortiz, Antonio Salmerón-García, José Hernández-Jiménez

Publikováno v: International Journal of Biological Macromolecules. 118:511-524

Research into stress and stability is essential during the development of therapeutic proteins to ensure quality and safety of the final medicine. Greater knowledge of the effects of stress on aggregation can help avoid undesirable conformational and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::692c6a79fe182fdaabf241f721aaf59a
https://doi.org/10.1016/j.ijbiomac.2018.06.105

Zobrazit plný text záznamu

The Effects of Light-Accelerated Degradation on the Aggregation of Marketed Therapeutic Monoclonal Antibodies Evaluated by Size-Exclusion Chromatography With Diode Array Detection

Autor: Luis Fermín Capitán-Vallvey, Celia Vélez, Natalia Navas, José Hernández-Jiménez, José Cabeza, Antonio Salmerón-García

Publikováno v: Journal of Pharmaceutical Sciences. 105:1405-1418

Research into the effects that exposure to light can have on therapeutic proteins is essential for ensuring the quality and safety of the medicines in which they are used. It is important to understand the effects of light on aggregation to help avoi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bde7fd2647dad7030879442c4c29cd2
https://doi.org/10.1016/j.xphs.2016.01.012

Zobrazit plný text záznamu

Crinivirus and begomovirus detection in tomato plantlets and weeds associated to nurseries

Autor: Antony Solórzano Morales, Eduardo José Hernández Jiménez, Rosemarie W. Hammond, Natalia María Barboza Vargas, Ruth Mayela Castro Vásquez, Pilar Ramírez Fonseca

Publikováno v: Agronomía Mesoamericana, Volume: 28, Issue: 2, Pages: 477-488, Published: AUG 2017
Agronomía Mesoamericana, vol. 28(2), pp. 477-488
Kérwá
Universidad de Costa Rica
instacron:UCR

El objetivo de este trabajo fue detectar infecciones causadas por el Tomato chlorosis virus (ToCV) y begomovirus en plántulas de tomate, y en las arvenses de los alrededores de los invernaderos. En el período de un año, a partir de abril de 2008,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de7fcd59e182c904b3c1c5326f72ab14
https://doi.org/10.15517/ma.v28i2.25860

Zobrazit plný text záznamu

TCH-026 Long-Term Study of the Formation of Aggregates in Undiluted Cetuximab 5 mg/ml

Autor: Antonio Salmerón-García, N Navas-Iglesias, Luis Fermín Capitán-Vallvey, José Hernández-Jiménez, J Cabeza-Barrera, Antonio Martínez-Ortega

Publikováno v: European Journal of Hospital Pharmacy. 20:A78.1-A78

Background Cetuximab (Erbitux) is a chimeric monoclonal IgG1 antibody, an epidermal growth factor receptor (EGFR) inhibitor, given by intravenous infusion for the treatment of metastatic colorectal cancer and head and neck cancer. Cetuximab is produc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::69a6c9115f377e2cbe6b190087119c68
https://doi.org/10.1136/ejhpharm-2013-000276.217

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání