Zobrazeno 1 - 10
of 168
pro vyhledávání: '"José G Fernández-Bolaños"'
Autor:
Leyre Sánchez-Barrionuevo, Alejandro González-Benjumea, Almudena Escobar-Niño, María Teresa García, Óscar López, Inés Maya, José G Fernández-Bolaños, David Cánovas, Encarnación Mellado
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0166561 (2016)
The chemical synthesis of new lipophilic polyphenols with improved properties presents technical difficulties. Here we describe the selection, isolation and identification of lipolytic bacteria from food-processing industrial wastes, and their use fo
Externí odkaz:
https://doaj.org/article/4550df03f0dd45998be86ce53973f9cb
Autor:
I. Caroline Vaaland, Óscar López, Adrián Puerta, Miguel X. Fernandes, José M. Padrón, José G. Fernández-Bolaños, Magne O. Sydnes, Emil Lindbäck
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1, Pp 349-360 (2023)
The copper-catalysed azide-alkyne cycloaddition was applied to prepare three enantiomeric pairs of heterodimers containing a tacrine residue and a 1,4-dideoxy-1,4-imino-D-arabinitol (DAB) or 1,4-dideoxy-1,4-imino-L-arabinitol (LAB) moiety held togeth
Externí odkaz:
https://doaj.org/article/d1237b9cbbfb410ca4a715968aec2873
Autor:
Tereza Hofmanova, Carolina Marques, Alfonso T. García-Sosa, Óscar López, Luisa Leitzbach, Elisabete P. Carreiro, Aday González-Bakker, Adrián Puerta, Holger Stark, José M. Padrón, José G. Fernández-Bolaños, Anthony J. Burke
Publikováno v:
Results in Chemistry, Vol 6, Iss , Pp 101032- (2023)
The oxindole core is an important structural motif in many natural and synthetic substances with various biological activities including anticancer, antineurodegenerative, and antimicrobial properties. This report focuses on the synthesis and biologi
Externí odkaz:
https://doaj.org/article/75d359ef21d247a498f7e6bdb867b7b7
Autor:
Emanuela Berrino, Simone Carradori, Fabrizio Carta, Francesco Melfi, Marialucia Gallorini, Giulio Poli, Tiziano Tuccinardi, José G. Fernández-Bolaños, Óscar López, Jacobus P. Petzer, Anél Petzer, Paolo Guglielmi, Daniela Secci, Claudiu T. Supuran
Publikováno v:
Antioxidants, Vol 12, Iss 12, p 2044 (2023)
Neurodegenerative disorders (NDs) include a large range of diseases characterized by neural dysfunction with a multifactorial etiology. The most common NDs are Alzheimer’s disease and Parkinson’s disease, in which cholinergic and dopaminergic sys
Externí odkaz:
https://doaj.org/article/b5a1744f71ab47be8afc72bbec67ca7a
Autor:
Mónica Martínez-Montiel, Laura L. Romero-Hernández, Simone Giovannuzzi, Paloma Begines, Adrián Puerta, Ana I. Ahuja-Casarín, Miguel X. Fernandes, Penélope Merino-Montiel, Sara Montiel-Smith, Alessio Nocentini, José M. Padrón, Claudiu T. Supuran, José G. Fernández-Bolaños, Óscar López
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9401 (2023)
The involvement of carbonic anhydrases (CAs) in a myriad of biological events makes the development of new inhibitors of these metalloenzymes a hot topic in current Medicinal Chemistry. In particular, CA IX and XII are membrane-bound enzymes, respons
Externí odkaz:
https://doaj.org/article/a4496264b52546eaa59e6d1a313ac174
Autor:
Giulia Arrighi, Adrián Puerta, Andrea Petrini, Francisco J. Hicke, Alessio Nocentini, Miguel X. Fernandes, José M. Padrón, Claudiu T. Supuran, José G. Fernández-Bolaños, Óscar López
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 14, p 7685 (2022)
(1) Background: carbonic anhydrases (CAs) are attractive targets for the development of new anticancer therapies; in particular, CAs IX and XII isoforms are overexpressed in numerous tumors. (2) Methods: following the tail approach, we have appended
Externí odkaz:
https://doaj.org/article/11b43f6e67e04d8bac92f65f98a8dca1
Autor:
I. Caroline Vaaland, Óscar López, Adrián Puerta, Miguel X. Fernandes, José M. Padrón, José G. Fernández-Bolaños, Magne O. Sydnes, Emil Lindbäck
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry. 38:349-360
The copper-catalysed azide-alkyne cycloaddition was applied to prepare three enantiomeric pairs of heterodimers containing a tacrine residue and a 1,4-dideoxy-1,4-imino-D-arabinitol (DAB) or 1,4-dideoxy-1,4-imino-L-arabinitol (LAB) moiety held togeth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddfd1ce8d23b9e768ddd2eec3279b2d6
https://doi.org/10.1080/14756366.2022.2150762
https://doi.org/10.1080/14756366.2022.2150762
Autor:
María Ángeles Rosillo, Marina Sánchez-Hidalgo, María Luisa Castejón, Tatiana Montoya, Alejandro González-Benjumea, José G. Fernández-Bolaños, Catalina Alarcón-de-la-Lastra
Publikováno v:
Journal of Functional Foods, Vol 36, Iss , Pp 27-33 (2017)
The hallmark of rheumatoid arthritis (RA) pathology is characterized by both hyperproliferation of synovial fibroblasts (SFs) and massive infiltration of inflammatory immune cells. This study was conducted to evaluate the efficacy of hydroxytyrosol (
Externí odkaz:
https://doaj.org/article/a57ca25f2cb244baa2b9ebc7f57aa695
Autor:
Marina Aparicio-Soto, Marina Sánchez-Hidalgo, Ana Cárdeno, Alejandro González-Benjumea, José G. Fernández-Bolaños, Catalina Alarcón-de-la-Lastra
Publikováno v:
Journal of Functional Foods, Vol 29, Iss , Pp 84-92 (2017)
Current experimental studies suggest a beneficial role of dietary phenolic compounds on prevention and management of immune-inflammatory disorders. Systemic lupus erythematosus (SLE), a multisystemic autoimmune chronic disease, remains without an eff
Externí odkaz:
https://doaj.org/article/d831be8b478c4133aa51f31b9baa9794
Publikováno v:
Expert Opinion on Therapeutic Patents. 32:913-932
Alzheimer's disease (AD) constitutes one of the most devastating diseases, with an extraordinarily high increase expected for the next few years. Despite the numerous efforts so far, there is still no cure but just palliative treatments.The main topi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db1df8a2d00fad038369f3fd45f33770
https://doi.org/10.1080/13543776.2022.2083956
https://doi.org/10.1080/13543776.2022.2083956