Zobrazeno 1 - 10
of 181
pro vyhledávání: '"José Fernández Piqueras"'
Autor:
Antonio Lahera, Laura Vela-Martín, Pablo Fernández-Navarro, Pilar Llamas, José L. López-Lorenzo, Javier Cornago, Javier Santos, José Fernández-Piqueras, María Villa-Morales
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-13 (2024)
Abstract Precursor T-cell neoplasms (T-ALL/LBL) are aggressive hematological malignancies that arise from the malignant transformation of immature thymocytes. Despite the JAK/STAT pathway is recurrently altered in these neoplasms, there are not pharm
Externí odkaz:
https://doaj.org/article/c8037d4ae28942409f7da1cc7c6cb1b9
Autor:
Pilar López-Nieva, Iria González-Vasconcellos, Laura González-Sánchez, María A. Cobos-Fernández, Sara Ruiz-García, Raúl Sánchez Pérez, Ángel Aroca, José Fernández-Piqueras, Javier Santos
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract In the quest for more effective radiation treatment options that can improve both cell killing and healthy tissue recovery, combined radiation therapies are lately in the spotlight. The molecular response to a combined radiation regime where
Externí odkaz:
https://doaj.org/article/f67abbf5a64040c4a4c1b91f3827cade
Autor:
José Luis Marín-Rubio, Laura Vela-Martín, Jack Gudgeon, Eduardo Pérez-Gómez, Frances R. Sidgwick, Matthias Trost, Debbie L. Cunningham, Javier Santos, José Fernández-Piqueras, María Villa-Morales
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 15157 (2022)
A reduction in FADD levels has been reported in precursor T-cell neoplasms and other tumor types. Such reduction would impact on the ability of tumor cells to undergo apoptosis and has been associated with poor clinical outcomes. However, FADD is als
Externí odkaz:
https://doaj.org/article/a49c703d31fd4dbd8cc1600e2aaa458d
Autor:
Pablo Fernández-Navarro, Pilar López-Nieva, Elena Piñeiro-Yañez, Gonzalo Carreño-Tarragona, Joaquín Martinez-López, Raúl Sánchez Pérez, Ángel Aroca, Fátima Al-Shahrour, María Ángeles Cobos-Fernández, José Fernández-Piqueras
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-10 (2019)
Abstract Background Acute T-cell lymphoblastic leukaemia (T-ALL) is an aggressive disorder derived from immature thymocytes. The variability observed in clinical responses on this type of tumours to treatments, the high toxicity of current protocols
Externí odkaz:
https://doaj.org/article/4844963c8bf847eb979d9da891212543
Autor:
Pilar López-Nieva, Pablo Fernández-Navarro, María Ángeles Cobos-Fernández, Iria González-Vasconcellos, Raúl Sánchez Pérez, Ángel Aroca, José Fernández-Piqueras, Javier Santos
Publikováno v:
Non-Coding RNA, Vol 8, Iss 2, p 26 (2022)
Circular RNAs (circRNAs) are suggested to play a discriminative role between some stages of thymocyte differentiation. However, differential aspects of the stage of mature single-positive thymocytes remain to be explored. The purpose of this study is
Externí odkaz:
https://doaj.org/article/e4089ec3c5174c6b996216c1abd000af
Autor:
Antonio Lahera, Pilar López‐Nieva, Hernán Alarcón, José L. Marín‐Rubio, María Á. Cobos‐Fernández, Pablo Fernández‐Navarro, Agustín F. Fernández, Laura Vela‐Martín, Isabel Sastre, Sara Ruiz‐García, Pilar Llamas, José L. López‐Lorenzo, Javier Cornago, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales
Publikováno v:
Scopus
Despite the Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway being frequently altered in T-ALL/LBL, no specific therapy has been approved for T-ALL/LBL patients with constitutive signalling by JAK/STAT, so there is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f71d0f2b00cba28da6de3f3d19757bf6
https://doi.org/10.1111/bjh.18694
https://doi.org/10.1111/bjh.18694
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Light can be employed as a tool to alter and manipulate matter in many ways. An example has been the implementation of optical trapping, the so called optical tweezers, in which light can hold and move small objects with 3D control. Of interest for t
Externí odkaz:
https://doaj.org/article/2a778360b2594b22b2811681201d37e9
Autor:
Pilar López-Nieva, Pablo Fernández-Navarro, Concepción Vaquero-Lorenzo, María Villa-Morales, Osvaldo Graña-Castro, María Ángeles Cobos-Fernández, José Luis López-Lorenzo, Pilar Llamas, Laura González-Sanchez, Isabel Sastre, Marina Pollan, Marcos Malumbres, Javier Santos, José Fernández-Piqueras
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-12 (2018)
Abstract Background Precursor T-cell lymphoblastic lymphomas (T-LBL) are rare aggressive hematological malignancies that mainly develop in children. As in other cancers, the loss of cell cycle control plays a prominent role in the pathogenesis in the
Externí odkaz:
https://doaj.org/article/8c05930c4cca48cc98e127c09078321c
Autor:
Miguel Quintanilla, Carmelo Bernabéu, Javier Dotor, Carlos Gamallo, José Fernández-Piqueras, Javier Santos, María Villa-Morales, Eduardo Pérez-Gómez
Endoglin is a membrane glycoprotein that acts as a coreceptor for transforming growth factor-β. We and others have previously suggested a function of endoglin as a tumor suppressor in epithelial cancer. Here, we study the expression of endoglin duri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fe6e82707f8e2b88f02d34881522f87
https://doi.org/10.1158/0008-5472.c.6495828
https://doi.org/10.1158/0008-5472.c.6495828
Autor:
Miguel Quintanilla, Carmelo Bernabéu, Javier Dotor, Carlos Gamallo, José Fernández-Piqueras, Javier Santos, María Villa-Morales, Eduardo Pérez-Gómez
Supplementary Figure 3 from A Role for Endoglin as a Suppressor of Malignancy during Mouse Skin Carcinogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a5c536282391477b4a7792063c9cd29
https://doi.org/10.1158/0008-5472.22368150.v1
https://doi.org/10.1158/0008-5472.22368150.v1