Zobrazeno 1 - 6
of 6
pro vyhledávání: '"José F. Hidalgo"'
Publikováno v:
Metabolites, Vol 10, Iss 12, p 489 (2020)
Structural analysis of constraint-based metabolic network models attempts to find the network’s properties by searching for subsets of suitable modes or Elementary Flux Modes (EFMs). One useful approach is based on Linear Program (LP) techniques, w
Externí odkaz:
https://doaj.org/article/79659b786d534cfd8b46221c1ea74d06
Publikováno v:
Bioinformatics
Motivation Elementary flux modes (EFMs) are a key tool for analyzing genome-scale metabolic networks, and several methods have been proposed to compute them. Among them, those based on solving linear programming (LP) problems are known to be very eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aae6f4682d295e308fa7d8b371a85cfa
http://europepmc.org/articles/PMC7390993
http://europepmc.org/articles/PMC7390993
Autor:
José F. Hidalgo, Antonio Ginés García-Saura, Fernando Gil-Ortiz, Juana Cabanes, Álvaro Sánchez-Ferrer, Rubén Zapata-Pérez
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Macrodomains constitute a conserved fold widely distributed that is not only able to bind ADP-ribose in its free and protein-linked forms but also can catalyse the hydrolysis of the latter. They are involved in the regulation of important cellular pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4296fed5bfc626514b396f48958d273f
Publikováno v:
Repositorio Digital de la Universidad Politécnica de Cartagena
instname
BMC Systems Biology
BMC Systems Biology, Vol 12, Iss S5, Pp 123-131 (2018)
instname
BMC Systems Biology
BMC Systems Biology, Vol 12, Iss S5, Pp 123-131 (2018)
Background Although cellular metabolism has been widely studied, its fully comprehension is still a challenge. A main tool for this study is the analysis of meaningful pieces of knowledge called modes and, in particular, specially interesting classes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42ad99cf616407da51ae2e9165f1639d
https://hdl.handle.net/10317/7776
https://hdl.handle.net/10317/7776
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Poly-ADP-ribose polymerases (PARPs) are involved in the regulation of important cellular processes, such as DNA repair, aging and apoptosis, among others. They have been considered as promising therapeutic targets, since human cancer cells carrying B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::458a1516f5b61f1d4c14cc086daf0d3b
https://pubmed.ncbi.nlm.nih.gov/29795234
https://pubmed.ncbi.nlm.nih.gov/29795234
Publikováno v:
Bioinformatics and Biomedical Engineering ISBN: 9783319561479
IWBBIO (1)
IWBBIO (1)
Pathways and more precisely Elementary Flux Modes (EFM) are artefacts extracted from metabolic networks that are very useful to achieve the comprehension of a very specific metabolic function or dysfunction. Many methods to extract pathways have alre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bde06be3c4b4318f0a7ebcce03ca6f9f
https://doi.org/10.1007/978-3-319-56148-6_58
https://doi.org/10.1007/978-3-319-56148-6_58