Zobrazeno 1 - 10
of 130
pro vyhledávání: '"José E. Rodríguez-Borges"'
Autor:
Daiane Nascimento Maronde, Ivo E. Sampaio-Dias, Luís Pinto da Silva, Leandro M. O. Lourenço, José E. Rodríguez-Borges
Publikováno v:
Medical Sciences Forum, Vol 14, Iss 1, p 25 (2022)
Cancer is one of the main leading causes of death worldwide, and its treatment is highly complex and known to cause serious side effects for patients. Photodynamic therapy (PDT) has gained a worldwide impact as a promising alternative strategy to ove
Externí odkaz:
https://doaj.org/article/ad710608481142bda18c9b1fde65af24
Autor:
Patricia González-Berdullas, Renato B. Pereira, Cláudia Teixeira, José Pedro Silva, Carla M. Magalhães, José E. Rodríguez-Borges, David M. Pereira, Joaquim C. G. Esteves da Silva, Luís Pinto da Silva
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8271 (2022)
Cancer is still a challenging disease to treat, both in terms of harmful side effects and therapeutic efficiency of the available treatments. Herein, to develop new therapeutic molecules, we have investigated the anticancer activity of halogenated de
Externí odkaz:
https://doaj.org/article/2433a3bdd1a843a99d33be3569dcf0b2
Autor:
Carla M. Magalhães, Patricia González-Berdullas, Diana Duarte, Ana Salomé Correia, José E. Rodríguez-Borges, Nuno Vale, Joaquim C. G. Esteves da Silva, Luís Pinto da Silva
Publikováno v:
Biomedicines, Vol 9, Iss 9, p 1199 (2021)
Photodynamic therapy (PDT) is an anticancer therapeutic modality with remarkable advantages over more conventional approaches. However, PDT is greatly limited by its dependence on external light sources. Given this, PDT would benefit from new systems
Externí odkaz:
https://doaj.org/article/4e212e9f6bbf460eb1af146d63325cbb
Autor:
Luís Pinto da Silva, Carla M. Magalhães, Ara Núñez-Montenegro, Paulo J.O. Ferreira, Diana Duarte, José E. Rodríguez-Borges, Nuno Vale, Joaquim C.G. Esteves da Silva
Publikováno v:
Biomolecules, Vol 9, Iss 8, p 384 (2019)
Cancer is a very challenging disease to treat, both in terms of treatment efficiency and side-effects. To overcome these problems, there have been extensive studies regarding the possibility of improving treatment by employing combination therapy, an
Externí odkaz:
https://doaj.org/article/93641af7e9ee462daeda4febb68b4e75
Publikováno v:
Acta Crystallographica Section E, Vol 65, Iss 5, Pp o992-o993 (2009)
The title compound, C15H13N3O8, comprises two crystallographically independent molecules in the asymmetric unit. In the crystal, intermolecular C—H...O hydrogen bonds link the molecules and short C=O...π contacts are seen.
Externí odkaz:
https://doaj.org/article/036e5ac4b4fd4a6a9a517ec98fc9a971
Publikováno v:
Acta Crystallographica Section E, Vol 65, Iss 1, Pp o188-o188 (2009)
In the title compound, C20H20NO4P, the dihedral angle between the phenyl rings is 68.52 (7)°. In the crystal structure, the molecules are linked by a weak C—H...π(arene) interaction along [010] involving the phenyl CH group and the phenyl rings.
Externí odkaz:
https://doaj.org/article/7267a5a50ca54771ae3d68a282efe653
Autor:
Sara C. Silva-Reis, Ivo E. Sampaio-Dias, Vera M. Costa, Xavier Cruz Correia, Hugo F. Costa-Almeida, Xerardo García-Mera, José E. Rodríguez-Borges
Publikováno v:
ACS Chemical Neuroscience. 14:554-572
Autor:
Carla M. Magalhaes, Tanja Dučić, Renato B. Pereira, Patricia González-Berdullas, José E. Rodríguez-Borges, David M. Pereira, Joaquim C.G. Esteves da Silva, Manuel Algarra, Luís Pinto da Silva
Publikováno v:
Archives of Biochemistry and Biophysics. :109660
Autor:
Ivo E. Sampaio-Dias, Manuel Algarra, Xerardo García-Mera, José E. Rodríguez-Borges, María Isabel Loza, Cristina Alcoholado, Vera Marisa Costa, Beatriz L. Pires-Lima, Ana Reis-Mendes, José Brea
Publikováno v:
Journal of Medicinal Chemistry. 64:6209-6220
The control of Parkinson's disease (PD) is challenged by the motor and non-motor fluctuations as well as dyskinesias associated with levodopa long-term therapy. As such, pharmacological alternatives to reduce the reliance on this drug are needed. Mel
Autor:
Ivo E. Sampaio-Dias, José E. Rodríguez-Borges, A. Catarina V. D. dos Santos, Sara C. Silva-Reis, Xerardo García-Mera
Publikováno v:
New Journal of Chemistry. 44:21049-21063
Neurodegenerative diseases, such as Alzheimer's and Parkinson's diseases, are a class of heterogeneous pathologies of the central nervous system (CNS) affecting millions of people worldwide. CNS-related pathologies represent a global health burden in