Zobrazeno 1 - 10
of 128
pro vyhledávání: '"José E Pérez-Ortín"'
Autor:
Moran Kelbert, Antonio Jordán-Pla, Lola de Miguel-Jiménez, José García-Martínez, Michael Selitrennik, Adi Guterman, Noa Henig, Sander Granneman, José E Pérez-Ortín, Sebastián Chávez, Mordechai Choder
Publikováno v:
eLife, Vol 12 (2024)
To function effectively as an integrated system, the transcriptional and post-transcriptional machineries must communicate through mechanisms that are still poorly understood. Here, we focus on the zinc-finger Sfp1, known to regulate transcription of
Externí odkaz:
https://doaj.org/article/142d36e65ad542ed92936c9e6151ec17
Autor:
Vicente Arnau, Marina Barba-Aliaga, Gaurav Singh, Javier Ferri, José García-Martínez, José E Pérez-Ortín
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0272878 (2022)
Ribosomal DNA (rDNA) is the genetic loci that encodes rRNA in eukaryotes. It is typically arranged as tandem repeats that vary in copy number within the same species. We have recently shown that rDNA repeats copy number in the yeast Saccharomyces cer
Externí odkaz:
https://doaj.org/article/6ff862448bf14ad9832e112aa2151140
Autor:
José E Pérez-Ortín, Adriana Mena, Marina Barba-Aliaga, Abhyudai Singh, Sebastián Chávez, José García-Martínez
Publikováno v:
PLoS Genetics, Vol 17, Iss 4, p e1009520 (2021)
The adjustment of transcription and translation rates to the changing needs of cells is of utmost importance for their fitness and survival. We have previously shown that the global transcription rate for RNA polymerase II in budding yeast Saccharomy
Externí odkaz:
https://doaj.org/article/d9d65b5f365c4b32ad54e118269cdfd9
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0122709 (2015)
Nitrogen levels in grape-juices are of major importance in winemaking ensuring adequate yeast growth and fermentation performance. Here we used a comparative transcriptome analysis to uncover wine yeasts responses to nitrogen availability during ferm
Externí odkaz:
https://doaj.org/article/00553d6c582944c7adeb8db93210ec0c
Autor:
Daniel A Medina, Antonio eJordán-Pla, Gonzalo eMillán-Zambrano, Sebastián eChávez, Mordechai eChoder, José E Pérez-Ortín
Publikováno v:
Frontiers in Genetics, Vol 5 (2014)
The 5’ to 3’ exoribonuclease Xrn1 is a large protein involved in cytoplasmatic mRNA degradation as a critical component of the major decaysome. Its deletion in the yeast Saccharomyces cerevisiae is not lethal, but it has multiple physiological ef
Externí odkaz:
https://doaj.org/article/654513941cb140a4b8765e12d4a5c885
Autor:
Elena Garre, Lorena Romero-Santacreu, Manuela Barneo-Muñoz, Ana Miguel, José E Pérez-Ortín, Paula Alepuz
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61240 (2013)
The expression of ribosomal protein (RP) genes requires a substantial part of cellular transcription, processing and translation resources. Thus, the RP expression must be tightly regulated in response to conditions that compromise cell survival. In
Externí odkaz:
https://doaj.org/article/8686b0d3ab394ccdbaa7feaa6b24842c
Autor:
Laia Castells-Roca, José García-Martínez, Joaquín Moreno, Enrique Herrero, Gemma Bellí, José E Pérez-Ortín
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e17272 (2011)
We have analyzed the heat stress response in the yeast Saccharomyces cerevisiae by determining mRNA levels and transcription rates for the whole transcriptome after a shift from 25 °C to 37 °C. Using an established mathematical algorithm, theoretic
Externí odkaz:
https://doaj.org/article/1657b37d9a3847a285e60f86ffa70cf6
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e15442 (2010)
The amount of mRNA in a cell is the result of two opposite reactions: transcription and mRNA degradation. These reactions are governed by kinetics laws, and the most regulated step for many genes is the transcription rate. The transcription rate, whi
Externí odkaz:
https://doaj.org/article/11e991a668494aa2b302c42b83834430
Autor:
Vicent Pelechano, Silvia Jimeno-González, Alfonso Rodríguez-Gil, José García-Martínez, José E Pérez-Ortín, Sebastián Chávez
Publikováno v:
PLoS Genetics, Vol 5, Iss 8, p e1000614 (2009)
Transcription elongation by RNA polymerase II was often considered an invariant non-regulated process. However, genome-wide studies have shown that transcriptional pausing during elongation is a frequent phenomenon in tightly-regulated metazoan genes
Externí odkaz:
https://doaj.org/article/70e1aa7b2b854d0388dcbf48c0eb5e77
Autor:
José E. Pérez-Ortín, Sebastián Chávez
Publikováno v:
Pérez Ortín, José Enrique Chávez, Sebastián 2022 Nucleo-cytoplasmic shuttling of RNA-binding factors: mRNA buffering and beyond Biochimica Et Biophysica Acta-Gene Regulatory Mechanisms 1865 194849
RODERIC. Repositorio Institucional de la Universitat de Valéncia
Universitat Politècnica de Catalunya (UPC)
RODERIC. Repositorio Institucional de la Universitat de Valéncia
Universitat Politècnica de Catalunya (UPC)
Gene expression is a highly regulated process that adapts RNAs and proteins content to the cellular context. Under steady-state conditions, mRNA homeostasis is robustly maintained by tight controls that act on both nuclear transcription and cytoplasm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6d7a7da14dd33fb799bc1c6299d6b68
https://hdl.handle.net/10668/22026
https://hdl.handle.net/10668/22026
