Dynamics of broad H3K4me3 domains uncover an epigenetic switch between cell identity and cancer-related genes

Autor: Mathieu Simonin, Denis Puthier, Guillaume Charbonnier, Iris Manosalva, Aneta Mikulasova, Eve-Lyne Mathieu, Pierre Ferrier, Charlotte Smith, José David Abad Flores, Mohamed Belhocine, Lydie Pradel, Vahid Asnafi, Salvatore Spicuglia, Daniel Rico, Lisa J. Russell, Hendrik G. Stunnenberg, Joost H.A. Martens, Muhammad Ahmad Maqbool, Agata Cieslak

Publikováno v: Genome Research
Genome Research, 2022, 32 (7), pp.1328-1342. ⟨10.1101/gr.266924.120⟩
Genome Research, 32, 7, pp. 1328-1342
Genome Research, 32, 1328-1342

International audience; Broad domains of H3K4 methylation have been associated with consistent expression of tissue-specific, cell identity, and tumor suppressor genes. Here, we identified broad domain–associated genes in healthy human thymic T cel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a75170c150852c64dce79a2210ba5f37
https://pubmed.ncbi.nlm.nih.gov/34162697