Zobrazeno 1 - 10
of 23
pro vyhledávání: '"José Carlos Segovia"'
Autor:
Cristina Mesa-Núñez, Diego Leon-Rico, Montserrat Aldea, Carlos Damián, Raquel Sanchez-Baltasar, Rebeca Sanchez, Omaira Alberquilla, José Carlos Segovia, Juan Antonio Bueren, Elena Almarza
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-9 (2020)
Abstract Background CD18 is the common beta subunit of β2 integrins, which are expressed on hematopoietic cells. β2 integrins are essential for cell adhesion and leukocyte trafficking. Methods Here we have analyzed the expression of CD18 in differe
Externí odkaz:
https://doaj.org/article/78847a9577544b7098f4252a48c057e3
Generation of NKX2.5GFP Reporter Human iPSCs and Differentiation Into Functional Cardiac Fibroblasts
Autor:
Leyre López-Muneta, Javier Linares, Oscar Casis, Laura Martínez-Ibáñez, Arantxa González Miqueo, Jaione Bezunartea, Ana Maria Sanchez de la Nava, Mónica Gallego, María Eugenia Fernández-Santos, Juan Roberto Rodriguez-Madoz, Xabier L. Aranguren, Francisco Fernández-Avilés, José Carlos Segovia, Felipe Prósper, Xonia Carvajal-Vergara
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2022)
Direct cardiac reprogramming has emerged as an interesting approach for the treatment and regeneration of damaged hearts through the direct conversion of fibroblasts into cardiomyocytes or cardiovascular progenitors. However, in studies with human ce
Externí odkaz:
https://doaj.org/article/18096c79bf8a442fbff2dd48d63ad000
Autor:
José Carlos Segovia Martín
Publikováno v:
Informes de la Construccion, Vol 54, Iss 479, Pp 72-72 (2002)
Externí odkaz:
https://doaj.org/article/0f7987a4568b4af0826768aa7b09efe3
Autor:
Nerea Lazcanoiturburu, Juan García‐Sáez, Carlos González‐Corralejo, Cesáreo Roncero, Julián Sanz, Carlos Martín‐Rodríguez, M Pilar Valdecantos, Adoración Martínez‐Palacián, Laura Almalé, Paloma Bragado, Silvia Calero‐Pérez, Almudena Fernández, María García‐Bravo, Carmen Guerra, Lluis Montoliu, José Carlos Segovia, Ángela M Valverde, Isabel Fabregat, Blanca Herrera, Aránzazu Sánchez
Publikováno v:
The Journal of Pathology. 258:312-324
Despite the well-known hepatoprotective role of the epidermal growth factor receptor (EGFR) pathway upon acute damage, its specific actions during chronic liver disease, particularly cholestatic injury, remain ambiguous and unresolved. Here, we analy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35be14be174367ba69dde5bd8b30806d
https://doi.org/10.1002/path.6002
https://doi.org/10.1002/path.6002
Autor:
Raquel Sanchez-Baltasar, Aida Garcia-Torralba, Virginia Nieto-Romero, Angustias Page, Andrea Molinos-Vicente, Sergio López-Manzaneda, Isabel Ojeda-Pérez, Angel Ramirez, Manuel Navarro, José Carlos Segovia, María García-Bravo
Publikováno v:
The CRISPR Journal. 5:422-434
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a051924ef55e732e3cb7de2788c405da
https://doi.org/10.1089/crispr.2022.0013
https://doi.org/10.1089/crispr.2022.0013
Autor:
Andrés Miguez, Cinta Gomis, Cristina Vila, Marta Monguió-Tortajada, Sara Fernández-García, Georgina Bombau, Mireia Galofré, María García-Bravo, Phil Sanders, Helena Fernández-Medina, Blanca Poquet, Cristina Salado-Manzano, Santiago Roura, Jordi Alberch, José Carlos Segovia, Nicholas D. Allen, Francesc E. Borràs, Josep M. Canals
Huntington's disease (HD) is an incurable inherited brain disorder characterized by massive degeneration of striatal neurons, which correlates with abnormal accumulation of misfolded mutant huntingtin (mHTT) protein. Research on HD has been hampered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ef0006a11fa5cb7df1d1c747dada069
https://doi.org/10.21203/rs.3.rs-2154496/v1
https://doi.org/10.21203/rs.3.rs-2154496/v1
Autor:
Ami J Shah, José Luis López Lorenzo, Julian Sevilla, Susana Navarro, Lucía Llanos, Begoña Perez de Camino Gaisse, Sol Sánchez, Josune Zubicaray, Bert Glader, May Chien, Oscar Quintana-Bustamante, Miriam Zeini, Grace Choi, Eileen Nicoletti, Gayatri Rao, Maria Grazia Roncarolo, Juan Bueren, Jonathan Schwartz, José Carlos Segovia
Publikováno v:
Transplantation and Cellular Therapy. 29:S225-S226
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68dc36c18f93d15b18c7d331db475945
https://doi.org/10.1016/s2666-6367(23)00362-7
https://doi.org/10.1016/s2666-6367(23)00362-7
Autor:
Jonathan D. Schwartz, Wilma Barcellini, Rachel F. Grace, Paola Bianchi, Alberto Zanella, José Luis López Lorenzo, Julián Sevilla, Ami J. Shah, Bertil Glader, Eileen Nicoletti, Susana Navarro Ordoñez, José Carlos Segovia
Publikováno v:
American Journal of Hematology. 97
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30bb117f426852a3fb70e785156b4895
https://doi.org/10.1002/ajh.26458
https://doi.org/10.1002/ajh.26458
Autor:
Luis Javier Serrano, Mariano Garcia-Arranz, Juan A. De Pablo-Moreno, José Carlos Segovia, Rocío Olivera-Salazar, Damián Garcia-Olmo, Antonio Liras
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 10; Pages: 5802
Factor V deficiency, an ultra-rare congenital coagulopathy, is characterized by bleeding episodes that may be more or less intense as a function of the levels of coagulation factor activity present in plasma. Fresh-frozen plasma, often used to treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a009a27a87a63f483604d1849b39d031
https://doi.org/10.3390/ijms23105802
https://doi.org/10.3390/ijms23105802
Autor:
Sara Fañanas-Baquero, Matías Morín, Sergio Fernández, Isabel Ojeda-Perez, Mercedes Dessy-Rodriguez, Miruna Giurgiu, Juan A. Bueren, Miguel Angel Moreno-Pelayo, Jose Carlos Segovia, Oscar Quintana-Bustamante
Publikováno v:
Frontiers in Genome Editing, Vol 5 (2023)
Pyruvate kinase deficiency (PKD) is an autosomal recessive disorder caused by mutations in the PKLR gene. PKD-erythroid cells suffer from an energy imbalance caused by a reduction of erythroid pyruvate kinase (RPK) enzyme activity. PKD is associated
Externí odkaz:
https://doaj.org/article/9304ddc2d19f4b5a87e0230bce6ecc47