Zobrazeno 1 - 10
of 26
pro vyhledávání: '"José Carlos Alves Filho"'
Autor:
Maria Luiza Thorstenberg, Marcos Vinícius Rangel Ferreira, Natália Amorim, Claudio Canetti, Fernanda B. Morrone, José Carlos Alves Filho, Robson Coutinho-Silva
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The release of damage-associated molecular patterns, including uridine triphosphate (UTP) and adenosine triphosphate (ATP) to the extracellular milieu is a key component of innate immune response to infection. Previously, we showed that macrophage in
Externí odkaz:
https://doaj.org/article/39299c775f4d41bf92060dc8043fb106
Autor:
Pedro Xavier-Elsas, Bianca de Luca, Túlio Queto, Bruno Marques Vieira, Daniela Masid-de-Brito, Elizabeth Chen Dahab, José Carlos Alves Filho, Fernando Q. Cunha, Maria Ignez C. Gaspar-Elsas
Publikováno v:
Mediators of Inflammation, Vol 2015 (2015)
Interleukin- (IL-) 17A, a pleiotropic mediator of inflammation and autoimmunity, potently stimulates bone-marrow neutrophil production. To explore IL-17A effects on eosinopoiesis, we cultured bone-marrow from wild-type mice, or mutants lacking induci
Externí odkaz:
https://doaj.org/article/bcd742229b114de4b8cd21aa276fd858
Autor:
Juliana Escher Toller-Kawahisa, Carlos Hiroji Hiroki, Camila Meirelles de Souza Silva, Daniele Carvalho Nascimento, Gabriel Azevedo Públio, Timna Varela Martins, Luis Eduardo Alves Damasceno, Flávio Protásio Veras, Paula Ramos Viacava, Fábio Yuji Sukesada, Emily Anne Day, Alessia Zotta, Tristram Alexander Jasper Ryan, Rodrigo Moreira da Silva, Thiago Mattar Cunha, Norberto Peporine Lopes, Fernando de Queiroz Cunha, Luke Anthony John O’Neill, José Carlos Alves-Filho
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Neutrophils rely predominantly on glycolytic metabolism for their biological functions, including reactive oxygen species (ROS) production. Although pyruvate kinase M2 (PKM2) is a glycolytic enzyme known to be involved in metabolic reprogram
Externí odkaz:
https://doaj.org/article/e9048a7d82b3436bbdf0ceaf5f09651b
Autor:
Igor Santiago-Carvalho, Gislane Almeida-Santos, Bruna Gois Macedo, Caio Cesar Barbosa-Bomfim, Fabricio Moreira Almeida, Marcos Vinícios Pinheiro Cione, Trupti Vardam-Kaur, Mia Masuda, Sarah Van Dijk, Bruno Marcel Melo, Rogério Silva do Nascimento, Rebeka da Conceição Souza, Alba Lucínia Peixoto-Rangel, Robson Coutinho-Silva, Mario Hiroyuki Hirata, José Carlos Alves-Filho, José Maria Álvarez, Elena Lassounskaia, Henrique Borges da Silva, Maria Regina D’Império-Lima
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113448- (2023)
Summary: CD4+ T cells are key components of the immune response during lung infections and can mediate protection against tuberculosis (TB) or influenza. However, CD4+ T cells can also promote lung pathology during these infections, making it unclear
Externí odkaz:
https://doaj.org/article/fe5978ef17a34b0d8f92e8f6d5272a3f
Autor:
Cristhiane Favero Aguiar, Felipe Corrêa-da-Silva, Michelangelo Bauwelz Gonzatti, Monara Kaelle Angelim, Marco Antonio Pretti, Gustavo Gastão Davanzo, Bianca Gazieri Castelucci, Lauar Brito Monteiro, Gisele Castro, João Victor Virgilio-da-Silva, Guilherme Ribeiro, Vitor Jaccomo, Mirella C. Pereira Andrade, Webster Leonardo Costa, Victor Gambarini, Fernanda Fernandes Terra, José Carlos Alves-Filho, Niels Olsen Saraiva Câmara, Mariana Boroni, Alexandre Castro Keller, Pedro M. Moraes-Vieira
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 112035- (2023)
Summary: Invariant natural killer T (iNKT) cells are a distinct population of lymphocytes characterized by their reactivity to glycolipids presented by CD1d. iNKT cells are found throughout the body, and little is known about their tissue-specific me
Externí odkaz:
https://doaj.org/article/85e257cc4eb746359d828db5eda7894e
Autor:
Daiana Drehmer, João Paulo Mesquita Luiz, Cesar Augusto Speck Hernandez, José Carlos Alves-Filho, Tracy Hussell, Paul Andrew Townsend, Salvador Moncada
Publikováno v:
Redox Biology, Vol 54, Iss , Pp 102350- (2022)
Production of nitric oxide (NO) has been demonstrated in several malignancies, however its role remains not fully understood, specifically in relation to the metabolic and functional implications that it may have on immune cells participating in tumo
Externí odkaz:
https://doaj.org/article/b4f0f96a2a354b458be8337cb813226c
Autor:
Patrícia Brito Rodrigues, Giovanni Freitas Gomes, Monara K. S. C. Angelim, Gabriela F. Souza, Stefanie Primon Muraro, Daniel A. Toledo-Teixeira, Bruna Amanda Cruz Rattis, Amanda Stephane Passos, Laís Passarielo Pral, Vinícius de Rezende Rodovalho, Arilson Bernardo dos Santos P. Gomes, Valquíria Aparecida Matheus, André Saraiva Leão Marcelo Antunes, Fernanda Crunfli, Krist Helen Antunes, Ana Paula Duarte de Souza, Sílvio Roberto Consonni, Luiz Osório Leiria, José Carlos Alves-Filho, Thiago M. Cunha, Pedro M. M. Moraes-Vieira, José Luiz Proença-Módena, Marco Aurélio R. Vinolo
Publikováno v:
Cells, Vol 11, Iss 16, p 2572 (2022)
Clinical and experimental data indicate that severe acute respiratory syndrome coronavirus (SARS-CoV)-2 infection is associated with significant changes in the composition and function of intestinal microbiota. However, the relevance of these effects
Externí odkaz:
https://doaj.org/article/cb41d2ea83e24270abeeb71a27f47abc
Autor:
Marco Tulio R Gomes, Erika S Guimarães, Fabio V Marinho, Isabella Macedo, Eric R G R Aguiar, Glen N Barber, Pedro M M Moraes-Vieira, José Carlos Alves-Filho, Sergio C Oliveira
Publikováno v:
PLoS Pathogens, Vol 17, Iss 5, p e1009597 (2021)
Macrophages metabolic reprogramming in response to microbial insults is a major determinant of pathogen growth or containment. Here, we reveal a distinct mechanism by which stimulator of interferon genes (STING), a cytosolic sensor that regulates inn
Externí odkaz:
https://doaj.org/article/98df6c9fca4b474eb2a3b01d298e7c2d
Autor:
Carlos Alexandre Curylofo Corsi, Claudia Tarcila Gomes Sares, Fabiola Mestriner, Jéssyca Michelon-Barbosa, Vinicius Flora Dugaich, Timna Varela Martins, Alex Martins Násare, Roberta Ribeiro Costa Rosales, Maria Cecília Jordani, José Carlos Alves-Filho, Rodolfo Borges dos Reis, Mauricio Serra Ribeiro, Christiane Becari
Publikováno v:
Cell and Tissue Banking.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21cbdce36641291ec84f79b3fe8a7851
https://doi.org/10.1007/s10561-023-10091-3
https://doi.org/10.1007/s10561-023-10091-3
Autor:
Raiany Santos, Priscila C. Campos, Marcella Rungue, Victor Rocha, David Santos, Viviani Mendes, Fabio V. Marinho, Flaviano Martins, Mayra F. Ricci, Diego C. dos Reis, Geovanni D. Cassali, José Carlos Alves-Filho, Angelica T. Vieira, Sergio C. Oliveira
Publikováno v:
Pathogens, Vol 9, Iss 5, p 328 (2020)
The ST2 receptor plays an important role in the gut such as permeability regulation, epithelium regeneration, and promoting intestinal immune modulation. Here, we studied the role of ST2 receptor in a murine model of oral infection with Brucella abor
Externí odkaz:
https://doaj.org/article/fc7eb32c643041c5b1c0f0223fffd516