Zobrazeno 1 - 9
of 9
pro vyhledávání: '"José C, Quilles"'
Autor:
Francisca S Borges, José C Quilles, Lucas B Lorenzon, Caroline R Espada, Felipe Freitas-Castro, Tânia P A Defina, Fabíola B Holetz, Angela K Cruz
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0292152 (2024)
In the protozoan parasite Leishmania, most genes encoding for ribosomal proteins (RPs) are present as two or more copies in the genome. However, their untranslated regions (UTRs) are predominantly divergent and might be associated with a distinct reg
Externí odkaz:
https://doaj.org/article/cdd62abe89a644a783d583c35fe89490
Autor:
Lucas, Lorenzon, José C, Quilles, Gustavo Daniel, Campagnaro, Lissur, Azevedo Orsine, Leticia, Almeida, Flavio, Veras, Rubens Daniel, Miserani Magalhães, Juliana, Alcoforado Diniz, Tiago, Rodrigues Ferreira, Angela, Kaysel Cruz
Publikováno v:
ACS infectious diseases. 8(3)
In trypanosomatids, regulation of gene expression occurs mainly at the posttranscriptional level, and RNA-binding proteins (RBPs) are key players in determining the fates of transcripts. RBPs are targets of protein arginine methyltransferases (PRMTs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::496e464fac7c1ce3ed8955f103966c4b
https://pubmed.ncbi.nlm.nih.gov/35226477
https://pubmed.ncbi.nlm.nih.gov/35226477
Publikováno v:
Applied Microbiology: Theory ＆ Technology. :66-80
Drug discovery and development is a multi and interdisciplinary process that includes chemistry and biology understanding. Though, drug discovery is an expensive and time-consuming process, promoting the lack of new drugs approval in recent years. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96613ea3da67c40dc415c3c69be24f36
https://doi.org/10.37256/amtt.122020413
https://doi.org/10.37256/amtt.122020413
Autor:
Lucas Lorenzon, José C. Quilles, Gustavo Daniel Campagnaro, Lissur Azevedo Orsine, Leticia Almeida, Flavio Veras, Rubens Daniel Miserani Magalhães, Juliana Alcoforado Diniz, Tiago Rodrigues Ferreira, Angela Kaysel Cruz
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5a0006ae5bb8fd3c7f02e12d739d13b
Autor:
J. Alcoforado Diniz, Tiago R. Ferreira, Lucas B. Lorenzon, Rubens Daniel Miserani Magalhães, Flávio Protaso Veras, G. D. Campagnaro, Luiz Gustavo de Almeida, José C. Quilles, Angela K. Cruz
In trypanosomatids, regulation of gene expression occurs mainly at the posttranscriptional level, and RNA-binding proteins (RBPs) are key players in determining the fates of transcripts. RBPs are major targets of protein arginine methyltransferases (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d9b314863a79ba7819f770efc7444c2
https://doi.org/10.1101/2021.09.22.461376
https://doi.org/10.1101/2021.09.22.461376
Autor:
Anwar Shamim, Pedro Henrique Jatai Batista, Carlos A. Montanari, Sérgio de Albuquerque, José C. Quilles, Daiane Y. Tezuka, Carla D. Lopes, Andrei Leitão
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Chagas disease affects several countries around the world with health and sanitation problems. Cysteine proteases are essential for the virulence and replication of the Trypanosoma cruzi, being modulated by dipeptidyl nitriles and derivatives. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c36fbd643ebba86a0443331dc32db00
Autor:
Pedro Henrique Jatai Batista, Samelyn da Costa Martins Silva, Murillo Dorileo Leite Bernardi, José C. Quilles, Carlos A. Montanari, Camila de Melo Romero Rocha, Andrei Leitão
Publikováno v:
Anti-cancer agents in medicinal chemistry. 19(1)
Background: Pancreatic cancer is one of the most aggressive types with high mortality in patients. Therefore, studies to discover new drugs based on cellular targets have been developed to treat this disease. Due to the importance of Cysteine Proteas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acc94f6cbd6096c2628aed0a2af08d04
https://pubmed.ncbi.nlm.nih.gov/30370859
https://pubmed.ncbi.nlm.nih.gov/30370859
Autor:
Fernanda L. Ribeiro, Carla D. Lopes, Sérgio de Albuquerque, José C. Quilles, Andrei Leitão, Carlos A. Montanari, Charles A. Laughton, Daiane Y. Tezuka
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Cysteine proteases are involved in critical cell processes to the protozoa from Leishmania genus, and their inhibition is a therapeutic alternative to treat the disease. In this work, derivatives of dipeptidyl nitriles acting as reversible covalent i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e71bb0eb35407de39708a85a9906d7a2
https://pubmed.ncbi.nlm.nih.gov/30954455
https://pubmed.ncbi.nlm.nih.gov/30954455
Autor:
Jr, José C. Quilles, Bernardi, Murillo D.L., Batista, Pedro H.J., Silva, Samelyn C.M., Rocha, Camila M.R., Montanari, Carlos A., Leitão, Andrei
Publikováno v:
Anti-Cancer Agents in Medicinal Chemistry; January 2019, Vol. 19 Issue: 1 p112-120, 9p