Zobrazeno 1 - 8
of 8
pro vyhledávání: '"José Bono-Yagüe"'
Autor:
José Bono-Yagüe, Ana Pilar Gómez-Escribano, José María Millán, Rafael Pascual Vázquez-Manrique
Publikováno v:
Antioxidants, Vol 9, Iss 7, p 577 (2020)
Huntington disease (HD) is a neurodegenerative condition and one of the so-called rare or minority diseases, due to its low prevalence (affecting 1–10 of every 100,000 people in western countries). The causative gene, HTT, encodes huntingtin, a pro
Externí odkaz:
https://doaj.org/article/07ea54a2d80b42f4b6decf1bf9e1534a
Autor:
Marta Vela, María Adelaida García-Gimeno, Ana Sanchis, José Bono-Yagüe, José Cumella, Laura Lagartera, Concepción Pérez, Eva-María Priego, Angela Campos, Pascual Sanz, Rafael P. Vázquez-Manrique, Ana Castro
Publikováno v:
ACS Chem Neurosci
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
49 páginas, 8 figuras, 2 tablas, 1 esquema. Contiene material suplementario
Aggregation of mutant huntingtin, because of an expanded polyglutamine track, underlies the cause of neurodegeneration in Huntington disease (HD). However, it remains u
Aggregation of mutant huntingtin, because of an expanded polyglutamine track, underlies the cause of neurodegeneration in Huntington disease (HD). However, it remains u
Autor:
David, Brinvillier, Melissa, Barrast, Petra, Couderc-Murillo, José, Bono-Yagüe, Alain, Rousteau, Ana Pilar, Gómez Escribano, Marcos V, Palmeira-Mello, Antonio, Doménech-Carbó, Nady, Passe-Coutrin, Muriel, Sylvestre, Rafael P, Vázquez-Manrique, Gerardo, Cebrián-Torrejón
Publikováno v:
ACS omega. 7(19)
Neurodegenerative disorders, caused by prone-to-aggregation proteins, such as Alzheimer disease or Huntington disease, share other traits such as disrupted homeostasis of essential metal ions, like copper. In this context, in an attempt to identify C
Autor:
S. C. Torres-Sánchez, José Bono-Yagüe, María Dolores Sequedo, V. Fornés-Ferrer, JM Millán, Pascual Sanz, Maria Adelaida Garcia-Gimeno, David Hervás, Ana Pilar Gómez-Escribano, Rafael P. Vázquez-Manrique
Publikováno v:
PHARMACOLOGICAL RESEARCH
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Digital.CSIC. Repositorio Institucional del CSIC
Pharmacological research
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Digital.CSIC. Repositorio Institucional del CSIC
Pharmacological research
11 páginas, 4 figuras. Supplementary material related to this article can be found, in the online version, at doi: https://doi.org/10.1016/j.phrs.2020.105105.
Expression of abnormally long polyglutamine (polyQ) tracks is the source of a range o
Expression of abnormally long polyglutamine (polyQ) tracks is the source of a range o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc3673aa7815898f2203a6aa5b51d7b9
http://hdl.handle.net/10261/219295
http://hdl.handle.net/10261/219295
Publikováno v:
Antioxidants, Vol 9, Iss 577, p 577 (2020)
Antioxidants
Antioxidants
Huntington disease (HD) is a neurodegenerative condition and one of the so-called rare or minority diseases, due to its low prevalence (affecting 1–10 of every 100,000 people in western countries). The causative gene, HTT, encodes huntingtin, a pro
I20 Synergistic combinations of metformin and salicylate reduce polyglutamine toxicity in c. elegans
Autor:
Juan A. Burguera, David Hervás, José M. Millán, Carmen Peiró, Ana Pilar Gómez-Escribano, Rafael P. Vázquez-Manrique, M Dolores Sequedo, Victoria Fornés-Ferrer, José Bono-Yagüe
Publikováno v:
Experimental therapeutics – preclinical.
Autor:
Rafael P. Vázquez-Manrique, Q Cheng-Zhang, Carmen Peiró, José Bono-Yagüe, Joaquín Cañizares, Ana Pilar Gómez-Escribano, José Blanca, Sequedo, José M. Millán, O Burton Nicholas, I Real-Arévalo, M Seco, A Laoz, Juan A. Burguera
Publikováno v:
Pathogenic mechanisms.
Toxicity induced by proteins containing polyglutamines (polyQs) is the cause of different neurodegenerative diseases, such as Huntington’s disease (HD). Mutant huntingtin (mHtt) is prone to aggregation, due to an abnormally long polyQ at the N-term
Autor:
Bono-Yagüe, José, Gómez-Escribano, Ana Pilar, Millán, José María, Vázquez-Manrique, Rafael Pascual
Publikováno v:
Antioxidants; Jul2020, Vol. 9 Issue 7, p577, 1p