Zobrazeno 1 - 10
of 81
pro vyhledávání: '"José B Pereira-Leal"'
Autor:
Daisuke Ito, Sihem Zitouni, Swadhin Chandra Jana, Paulo Duarte, Jaroslaw Surkont, Zita Carvalho-Santos, José B Pereira-Leal, Miguel Godinho Ferreira, Mónica Bettencourt-Dias
Publikováno v:
eLife, Vol 8 (2019)
The centrosome is composed of two centrioles surrounded by a microtubule-nucleating pericentriolar material (PCM). Although centrioles are known to regulate PCM assembly, it is less known whether and how the PCM contributes to centriole assembly. Her
Externí odkaz:
https://doaj.org/article/e59e8274cae3401daab82b790a408359
Autor:
Joana Cardoso, Marta Mesquita, António Dias Pereira, Mónica Bettencourt-Dias, Paula Chaves, José B Pereira-Leal
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0161967 (2016)
Barrett's esophagus is the major risk factor for esophageal adenocarcinoma. It has a low but non-neglectable risk, high surveillance costs and no reliable risk stratification markers. We sought to identify early biomarkers, predictive of Barrett's ma
Externí odkaz:
https://doaj.org/article/1eb9315c6c934835982827ff9101f14c
Autor:
Patricia Reed, Magda L Atilano, Renato Alves, Egbert Hoiczyk, Xinwei Sher, Nathalie T Reichmann, Pedro M Pereira, Terry Roemer, Sérgio R Filipe, José B Pereira-Leal, Petros Ligoxygakis, Mariana G Pinho
Publikováno v:
PLoS Pathogens, Vol 11, Iss 5, p e1004891 (2015)
Many important cellular processes are performed by molecular machines, composed of multiple proteins that physically interact to execute biological functions. An example is the bacterial peptidoglycan (PG) synthesis machine, responsible for the synth
Externí odkaz:
https://doaj.org/article/b143b2e0268d4dc794405f6ddbf5de0f
Autor:
Isabel Marques, Paulo Almeida, Renato Alves, Maria João Dias, Ana Godinho, José B Pereira-Leal
Publikováno v:
PLoS Computational Biology, Vol 10, Iss 1, p e1003404 (2014)
The interdisciplinary nature of bioinformatics makes it an ideal framework to develop activities enabling enquiry-based learning. We describe here the development and implementation of a pilot project to use bioinformatics-based research activities i
Externí odkaz:
https://doaj.org/article/bb6c7156d9854afca43bb110ed3f045a
Autor:
Yoan Diekmann, Elsa Seixas, Marc Gouw, Filipe Tavares-Cadete, Miguel C Seabra, José B Pereira-Leal
Publikováno v:
PLoS Computational Biology, Vol 7, Iss 10, p e1002217 (2011)
Rab proteins are small GTPases that act as essential regulators of vesicular trafficking. 44 subfamilies are known in humans, performing specific sets of functions at distinct subcellular localisations and tissues. Rab function is conserved even amon
Externí odkaz:
https://doaj.org/article/d593304552454ccca04b691bcf81e4d2
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e19117 (2011)
BackgroundHeme-copper oxygen reductases (HCOs) are the last enzymatic complexes of most aerobic respiratory chains, reducing dioxygen to water and translocating up to four protons across the inner mitochondrial membrane (eukaryotes) or cytoplasmatic
Externí odkaz:
https://doaj.org/article/9df2416dbc5a481c96087da26c9fb21a
Publikováno v:
PLoS Computational Biology, Vol 7, Iss 2, p e1001082 (2011)
Biological systems evolved to be functionally robust in uncertain environments, but also highly adaptable. Such robustness is partly achieved by genetic redundancy, where the failure of a specific component through mutation or environmental challenge
Externí odkaz:
https://doaj.org/article/33058c874f094642b534970cf9e57e0f
Autor:
Maria Gonçalves-Reis, Daniela Proença, Laura P. Frazão, João L. Neto, Sílvia Silva, Hugo Pinto-Marques, José B. Pereira-Leal, Joana Cardoso
Publikováno v:
Practical Laboratory Medicine, Vol 39, Iss , Pp e00365- (2024)
Objectives: To verify the analytical performance of the HepatoPredict kit, a novel tool developed to stratify Hepatocellular Carcinoma (HCC) patients according to their risk of relapse after a Liver Transplantation (LT). Methods: The HepatoPredict to
Externí odkaz:
https://doaj.org/article/2b3d0511a0994548ae142aa9c574a7a1
Autor:
Hugo Pinto-Marques, Joana Cardoso, Sílvia Silva, João L. Neto, Maria Gonçalves-Reis, Daniela Proença, Marta Mesquita, André Manso, Sara Carapeta, Mafalda Sobral, Antonio Figueiredo, Clara Rodrigues, Adelaide Milheiro, Ana Carvalho, Rui Perdigoto, Eduardo Barroso, José B. Pereira-Leal
Publikováno v:
Annals of surgery. 276(5)
Copyright © 2022 The Author(s). Published by Wolters Kluwer Health, Inc. OBJECTIVE: To propose a new decision algorithm combining biomarkers measured in a tumor biopsy with clinical variables, to predict recurrence after liver transplantation (LT).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf9db76a9ac4b616045f667114e7f152
https://pubmed.ncbi.nlm.nih.gov/35916378
https://pubmed.ncbi.nlm.nih.gov/35916378
Autor:
Cláudia Marques, Liliana Dinis, Inês Barreiros Mota, Juliana Morais, Shámila Ismael, José B. Pereira-Leal, Joana Cardoso, Pedro Ribeiro, Helena Beato, Mafalda Resende, Christophe Espírito Santo, Ana Paula Cortez, André Rosário, Diogo Pestana, Diana Teixeira, Ana Faria, Conceição Calhau
Publikováno v:
Journal of agricultural and food chemistry. 70(41)
Gut microbiota modulation might constitute a mechanism mediating the effects of beer on health. In this randomized, double-blinded, two-arm parallel trial, 22 healthy men were recruited to drink 330 mL of nonalcoholic beer (0.0% v/v) or alcoholic bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d876d614680a91fcbc1fb0b68187cf47
https://pubmed.ncbi.nlm.nih.gov/35834180
https://pubmed.ncbi.nlm.nih.gov/35834180