Viral RNA load in plasma is associated with critical illness and a dysregulated host response in COVID-19

Autor: Jesús F. Bermejo-Martin, Milagros González-Rivera, Raquel Almansa, Dariela Micheloud, Ana P. Tedim, Marta Domínguez-Gil, Salvador Resino, Marta Martín-Fernández, Pablo Ryan Murua, Felipe Pérez-García, Luis Tamayo, Raúl Lopez-Izquierdo, Elena Bustamante, César Aldecoa, José Manuel Gómez, Jesús Rico-Feijoo, Antonio Orduña, Raúl Méndez, Isabel Fernández Natal, Gregoria Megías, Montserrat González-Estecha, Demetrio Carriedo, Cristina Doncel, Noelia Jorge, Alicia Ortega, Amanda de la Fuente, Félix del Campo, José Antonio Fernández-Ratero, Wysali Trapiello, Paula González-Jiménez, Guadalupe Ruiz, Alyson A. Kelvin, Ali Toloue Ostadgavahi, Ruth Oneizat, Luz María Ruiz, Iria Miguéns, Esther Gargallo, Ioana Muñoz, Sara Pelegrin, Silvia Martín, Pablo García Olivares, Jamil Antonio Cedeño, Tomás Ruiz Albi, Carolina Puertas, Jose Ángel Berezo, Gloria Renedo, Rubén Herrán, Juan Bustamante-Munguira, Pedro Enríquez, Ramón Cicuendez, Jesús Blanco, Jesica Abadia, Julia Gómez Barquero, Nuria Mamolar, Natalia Blanca-López, Luis Jorge Valdivia, Belén Fernández Caso, María Ángeles Mantecón, Anna Motos, Laia Fernandez-Barat, Ricard Ferrer, Ferrán Barbé, Antoni Torres, Rosario Menéndez, José María Eiros, David J. Kelvin

Publikováno v: Critical Care, Vol 24, Iss 1, Pp 1-13 (2020)

Abstract Background COVID-19 can course with respiratory and extrapulmonary disease. SARS-CoV-2 RNA is detected in respiratory samples but also in blood, stool and urine. Severe COVID-19 is characterized by a dysregulated host response to this virus.

Externí odkaz: https://doaj.org/article/60fc039a753643adae89671cf2ace0f6

Patients with tracheostomy indication in an intensive care cohort☆

Autor: Ana Berrazueta-S. de Vega, Javier Romero-Pellejero, José Antonio Fernández-Ratero, María Esther Martínez-Barrio, Diana Armesto-Formoso, Maria del Valle-Ortiz

Publikováno v: Colombian Journal of Anesthesiology. 44:278-281

Introduction Tracheostomy is a procedure indicated for patients with extended mechanical ventilation. Objective The objective of the study was to learn about the technical characteristics, the appropriate timing for the procedure and its evolution. M

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9b45ddbdc7a827892d0547b41c1d121
https://doi.org/10.1097/01819236-201644040-00004

Benefits of early aggressive immunomodulatory therapy (tocilizumab and methylprednisolone) in COVID-19: Single center cohort study of 685 patients.

Autor: Luis BM; Infectious Diseases Unit, Internal Medicine, Hospital de Burgos, Spain., Miguel MB; Intensive Care, Hospital de Burgos, Spain., Pedro DL; Neurosurgery, Hospital de Burgos, Spain., David IP; Intensive Care, Hospital de Burgos, Spain., Itziar A; Pediatrics, Biocruces Bizkaia Health Research Institute, Hospital Universitario de Cruces, University of the Basque Country UPV/EHU, Baracaldo, Spain., Ana GH; Infectious Diseases Unit, Internal Medicine, Hospital de Burgos, Spain.; Neurosurgery, Hospital de Burgos, Spain., Enrique IJ; Systemic Autoimmune Diseases, Internal Medicine Department, Hospital de Burgos, Spain., María LV; Systemic Autoimmune Diseases, Internal Medicine Department, Hospital de Burgos, Spain., Noelia TF; Systemic Autoimmune Diseases, Internal Medicine Department, Hospital de Burgos, Spain., Julio César BB; Systemic Autoimmune Diseases, Internal Medicine Department, Hospital de Burgos, Spain., Marta UI; Pharmacy Department, Hospital de Burgos, Spain., Rodrigo SL; Anesthesiology Department, Hospital de Burgos, Spain., María CB; Reumatology Department, Hospital de Burgos, Spain., Andrés LM; Reumatology Department, Hospital de Burgos, Spain., Javier MI; Pneumology Department, Hospital de Burgos, Spain., Juan Pablo GM; Pneumology Department, Hospital de Burgos, Spain., Gerardo HF; Hematology Department, Hospital de Burgos, Spain., Carolina NF; Infectious Diseases Unit, Internal Medicine, Hospital de Burgos, Spain., Jorge BL; Internal Medicine, Hospital de Burgos, Spain., María FR; Infectious Diseases Unit, Internal Medicine, Hospital de Burgos, Spain., Fernando CT; Intensive Care, Hospital de Burgos, Spain., Sergio OE; Intensive Care, Hospital de Burgos, Spain., Lourdes FC; Intensive Care, Hospital de Burgos, Spain., María GE; Intensive Care, Hospital de Burgos, Spain., Gregoria ML; Microbiology Department, Hospital de Burgos, Spain., Adolfo SR; Pneumology Department, Hospital de Burgos, Spain., José Antonio FR; Intensive Care, Hospital de Burgos, Spain.

Publikováno v: Journal of translational autoimmunity [J Transl Autoimmun] 2021; Vol. 4, pp. 100086. Date of Electronic Publication: 2021 Feb 12.