Zobrazeno 1 - 10
of 151
pro vyhledávání: '"José Andrés, Yunes"'
Autor:
Bruna Coelho de Andrade, Gaby Renard, Adriano Gennari, Leonardo Luís Artico, José Ricardo Teixeira Júnior, Daniel Kuhn, Priscila Pini Zenatti Salles, Claucia Fernada Volken de Souza, Gustavo Roth, Jocelei Maria Chies, José Andrés Yunes, Luiz Augusto Basso
Publikováno v:
ACS Omega, Vol 9, Iss 32, Pp 34951-34963 (2024)
Externí odkaz:
https://doaj.org/article/5fce0fd996774cbeaeb3d880bce646a4
Autor:
Guilherme Navarro Nilo Giusti, Antonio Vítor Ribeiro, Patrícia Yoshioka Jotta, Florian Thonier, José Andrés Yunes, João Meidanis
Publikováno v:
eJHaem, Vol 4, Iss 3, Pp 770-774 (2023)
Abstract Assessment of minimal residual disease in acute lymphoblastic leukemia by immune repertoire NGS requires spiking CDR3 sequences at known quantities into the patient's sample. Recently, the EuroClonality‐NGS group released one of the most c
Externí odkaz:
https://doaj.org/article/235af646bb574808a9ffa39c408c8856
Autor:
Rafael Renatino Canevarolo, Carolina Pereira de Souza Melo, Nathalia Moreno Cury, Leonardo Luiz Artico, Juliana Ronchi Corrêa, Yanca Tonhasca Lau, Samara Sousa Mariano, Praneeth Reddy Sudalagunta, Silvia Regina Brandalise, Ana Carolina de Mattos Zeri, José Andrés Yunes
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
IntroductionMethotrexate (MTX), a folic acid antagonist and nucleotide synthesis inhibitor, is a cornerstone drug used against acute lymphoblastic leukemia (ALL), but its mechanism of action and resistance continues to be unraveled even after decades
Externí odkaz:
https://doaj.org/article/6f2af01611a945a1922eda33add0417b
Autor:
Leonardo Luís Artico, Juliana Silveira Ruas, José Ricardo Teixeira Júnior, Natacha Azussa Migita, Gustavo Seguchi, Xinghua Shi, Silvia Regina Brandalise, Roger Frigério Castilho, José Andrés Yunes
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9679 (2023)
Increased glycolytic metabolism plays an important role in B-cell precursor Acute Lymphoblastic Leukemia (BCP-ALL). We previously showed that IGFBP7 exerts mitogenic and prosuvival effects in ALL by promoting IGF1 receptor (IGF1R) permanence on the c
Externí odkaz:
https://doaj.org/article/76ebafb958074bbc9c0bdb597813ae13
Autor:
Nathália Moreno Cury, Tobias Mühlethaler, Angelo Brunelli Albertoni Laranjeira, Rafael Renatino Canevarolo, Priscila Pini Zenatti, Daniel Lucena-Agell, Isabel Barasoain, Chunhua Song, Dongxiao Sun, Sinisa Dovat, Rosendo Augusto Yunes, Andrea Enrico Prota, Michel Olivier Steinmetz, José Fernando Díaz, José Andrés Yunes
Publikováno v:
iScience, Vol 21, Iss , Pp 95-109 (2019)
Summary: Tubulin is one of the best validated anti-cancer targets, but most anti-tubulin agents have unfavorable therapeutic indexes. Here, we characterized the tubulin-binding activity, the mechanism of action, and the in vivo anti-leukemia efficacy
Externí odkaz:
https://doaj.org/article/67ad75df1ed143b6b2d81f30461805ab
Autor:
Gustavo Alencastro Veiga Cruzeiro, Karina Bezerra Salomão, Carlos Alberto Oliveira de Biagi Jr, Martin Baumgartner, Dominik Sturm, Régia Caroline Peixoto Lira, Taciani de Almeida Magalhães, Mirella Baroni Milan, Vanessa da Silva Silveira, Fabiano Pinto Saggioro, Ricardo Santos de Oliveira, Paulo Henrique dos Santos Klinger, Ana Luiza Seidinger, José Andrés Yunes, Rosane Gomes de Paula Queiroz, Sueli Mieko Oba-Shinjo, Carlos Alberto Scrideli, Suely Marie Kazue Nagahashi, Luiz Gonzaga Tone, Elvis Terci Valera
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-10 (2019)
Abstract Next-generation sequencing platforms are routinely used for molecular assignment due to their high impact for risk stratification and prognosis in medulloblastomas. Yet, low and middle-income countries still lack an accurate cost-effective p
Externí odkaz:
https://doaj.org/article/ac6cfc7ec6ce483ebbb41923ea82f3dc
Autor:
Iva Loureiro Hoffmann, Izilda Aparecida Cardinalli, José Andrés Yunes, Ana Luiza Seidinger, Ricardo Mendes Pereira
Publikováno v:
Revista Paulista de Pediatria, Vol 39 (2020)
ABSTRACT Objective: To describe the clinical, demographic, anatomopathological, molecular, and survival characteristics of patients with medulloblastoma. Methods: Retrospective study based on patient information obtained from the review of medical re
Externí odkaz:
https://doaj.org/article/5d539bbbadc7445abef43ac665c660b9
Autor:
Priscila Pini Zenatti, Natacha Azussa Migita, Nathália Moreno Cury, Rosângela Aparecida Mendes-Silva, Fabio Cesar Gozzo, Pedro Otavio de Campos-Lima, José Andrés Yunes, Silvia Regina Brandalise
Publikováno v:
EBioMedicine, Vol 30, Iss , Pp 158-166 (2018)
The drug l-asparaginase is a cornerstone in the treatment of acute lymphoblastic leukemia (ALL). The native E. coli l-asparaginase used in Brazil until recently has been manufactured by Medac/Kyowa. Then a decision was taken by the Ministry of Health
Externí odkaz:
https://doaj.org/article/07f36f903046424ea71f1f7b93ed843d
Autor:
Rodrigo Fernandes da Silva, Daniela Maira Cardozo, Gisele Olinto Libanio Rodrigues, Caroline Natânia de Souza-Araújo, Natacha Azussa Migita, Liliana Aparecida Lucci de Angelo Andrade, Sophie Derchain, José Andrés Yunes, Fernando Guimarães
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-12 (2017)
Abstract Background The spontaneous immortalization of primary malignant cells is frequently assigned to their genetic instability during in vitro culturing. In this study, the new epithelial ovarian cancer cell line CAISMOV24 was described and compa
Externí odkaz:
https://doaj.org/article/492e99646cc5430bb794c81e0f129afe
Autor:
Silvia R. Brandalise, Rosemary Assis, Angelo B. A. Laranjeira, José Andrés Yunes, Pedro O. de Campos-Lima
Publikováno v:
Experimental Hematology & Oncology, Vol 6, Iss 1, Pp 1-11 (2017)
Abstract Background Inflammation is a major feature of sickle cell disease (SCD). Low-dose methotrexate (MTX) has long been used in chronic inflammatory diseases. This pilot study examined the MTX effect on acute vaso-occlusive pain crises (VOC) in S
Externí odkaz:
https://doaj.org/article/0f2e816d33d54ee7ba79dc84f73a82f1