Zobrazeno 1 - 10
of 21
pro vyhledávání: '"José Almeida-Santos"'
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Severe COVID-19 patients show various immunological abnormalities including T-cell reduction and cytokine release syndrome, which can be fatal and is a major concern of the pandemic. However, it is poorly understood how T-cell dysregulation can contr
Externí odkaz:
https://doaj.org/article/6df1e178dc1a4da38274192b7752539a
Publikováno v:
Revista Rosa dos Ventos - Turismo e Hospitalidade. 13:1-10
Publikováno v:
Methods in Molecular Biology ISBN: 9781071626467
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e177ccfa23ae3ccec6d7e31cf6c1e6ab
https://doi.org/10.1007/978-1-0716-2647-4_6
https://doi.org/10.1007/978-1-0716-2647-4_6
Autor:
José Almeida-Santos, Rita Berkachy, Chanidapa Adele Tye, Jehanne Hassan, Bahire Kalfaoglu, Murray E. Selkirk, Masahiro Ono
CD4 T-cells require T-cell receptor (TCR) signalling for their activation and differentiation. Foxp3+ regulatory T-cells (Treg) are dependent on TCR signals for their differentiation and suppressive function. However, it is not fully known how TCR si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e646650249f636ca2821596d81a72980
https://doi.org/10.1101/2022.07.21.500987
https://doi.org/10.1101/2022.07.21.500987
Autor:
Jehanne Hassan, Elizabeth Appleton, Bahire Kalfaoglu, Malin Pedersen, José Almeida-Santos, Hisashi Kanemaru, Nobuko Irie, Shane Foo, Omnia Reda, Benjy J.Y. Tan, Il-mi Okazaki, Taku Okazaki, Yorifumi Satou, Kevin Harrington, Alan Melcher, Masahiro Ono
The blockade of the immune checkpoints PD-1 and CTLA-4 enhances T cell response. However, it is largely unknown how antigen-reactive T cells regulate their checkpoint expression in vivo and whether and how the checkpoint blockade can change activatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db8cb1d9af3e601a3c1d0591c82c161e
https://doi.org/10.1101/2022.07.19.500582
https://doi.org/10.1101/2022.07.19.500582
Publikováno v:
The Journal of Immunology. 206:978-986
The thymus produces precursors of both conventional T cells (Tconv; also known as effector T cells) and regulatory T cells (Treg) whose interactions prevent autoimmunity while allowing efficient protective immune responses. Tumors express a composite
Autor:
Carlos Eduardo Haas Hammes, Jennifer Bauer Eme, Simone Maria Sandi, Jóice dos Santos Bernardo, Karen Dannenhauer, Maria Luiza Cardinale Baptista, José Almeida Santos, Rudinei Picinini, Camila Carvalho de Melo
Publikováno v:
Revista Rosa dos Ventos - Turismo e Hospitalidade. 12:1-23
The text is a collective production by Amorcomtur! Study Group on Communication, Tourism, Lovingness and Autopoiesis, reflecting on challenges and signs of a worldwide post-pandemic, based on research that was announced like for Reverse Side of Turis
Autor:
Marie-Louise Bergman, Vasco Correia, Inês Amendoeira Cabral, Jocelyne Demengeot, José Almeida-Santos, Íris Caramalho
Publikováno v:
European Journal of Immunology
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
It is well established that therapeutic impairment of Foxp3+ Treg in mice and humans favors immune rejection of solid tumors. Less explored is the impact Foxp3 allelic variants may have on tumor incidence, progression and therapy. In this work, we te
Publikováno v:
Biochemical and Biophysical Research Communications
T-cells play key roles in immunity to COVID-19 as well as the development of severe disease. T-cell immunity to COVID-19 is mediated through differentiated CD4+ T-cells and cytotoxic CD8+ T-cells, although their differentiation is often atypical and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af21402c21d610222d3ba0b387968d05
http://hdl.handle.net/10044/1/83897
http://hdl.handle.net/10044/1/83897