Zobrazeno 1 - 10
of 23
pro vyhledávání: '"José Agustín Quincoces Suárez"'
Autor:
Carolina Passarelli Gonçalves, Alfredo Peña Ricardo, Mário Augusto Tremante, José Agustín Quincoces Suárez, José Matheus de Freitas Costa, Manuel Salustiano Almeida Saavedra
Publikováno v:
Current Organic Chemistry. 25:748-756
Some thiophenic derivatives show important biological activity or are used as intermediates in organic synthesis. For this reason, it is very important to develop new synthesis procedures with good yields and using few synthesis steps. The present wo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::844ef7b8e6c134ddd196f32ba9c1ddba
https://doi.org/10.2174/1385272825666210111112449
https://doi.org/10.2174/1385272825666210111112449
Autor:
Kevin Kalinsky, Joanne E. Mortimer, José Agustín Quincoces Suárez, Julie R. Nangia, Matt Suster, Mieke Ptaszynski, Pavani Chalasani, Vandana G. Abramson
Publikováno v:
Cancer Research. 81:PS12-20
Background: ZN-c5 is an orally bioavailable selective estrogen receptor degrader (SERD) that binds potently to the estrogen receptors alpha and beta. It shows improved activity over fulvestrant in human tumor xenograft models and activity in tumor mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad34b91fd6b132f938e46b6c40860692
https://doi.org/10.1158/1538-7445.sabcs20-ps12-20
https://doi.org/10.1158/1538-7445.sabcs20-ps12-20
Este livro é o único no mercado que parte de uma única via sintética, com vantagens em relação aos livros sobre heterociclos existentes no mercado. O livro compreende sete capítulos. No primeiro capítulo o leitor encontrará a definição sob
Autor:
Vanessa Soto-Cerrato, Durvanei Augusto Maria, Ricardo Pérez-Tomás, José Agustín Quincoces Suárez, Margarita Espona-Fiedler, Fernanda Faião-Flores
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Melanoma is one of the most aggressive types of skin cancer and its incidence rate is still increasing. All existing treatments are minimally effective. Consequently, new therapeutic agents for melanoma treatment should be developed. The DM-1 compoun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3b113ae580f4382f73ee4b4cd278082
https://doi.org/10.1007/s13277-013-0666-6
https://doi.org/10.1007/s13277-013-0666-6
Autor:
Dirk Michalik, Alexander Villinger, Udo Kragl, Dilver Peña Fuentes, José Agustín Quincoces Suárez, Heike Waechtler, Christian Vogel
Publikováno v:
ARKIVOC, Vol 2012, Iss 3, Pp 110-133 (2012)
A series of ribofuranosyl- and 2-deoxyribofuranosyl homo- and spacered-C-nucleosides have been synthesized by reaction of fully protected 3-(1-deoxy-β-D-ribofuranosyl-1-yl)propanal (1), 3-(1,2-dideoxy-β-D-ribofuranos-1-yl)propanal (14), 1-(1-desoxy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9ad80f002f58384fbce28e6d5bf0db3
https://doi.org/10.3998/ark.5550190.0013.310
https://doi.org/10.3998/ark.5550190.0013.310
Autor:
José Agustín Quincoces Suárez, Paulo Celso Pardi, Amarilis Scremin Paulino, Dirk Michalik, Niraldo Paulino, Carolina Passarelli, José Matheus de Freitas Costa, Priscila Vaultier, Laura Pisco
Publikováno v:
Pharmacology & Pharmacy. :348-357
This work describes the synthesis, antinociceptive and anti-inflammatory effect of O-prenyl derivatives: O-prenyl derivatives 2-(3-methylbut-2-enyloxy)acetophenone (L1) and 3-methoxy-4-(3-methylbut-2-enyloxy)benzaldehyde (V1). Treatment with L1- or V
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57dd5ab6dc307104e925da138a71e532
https://doi.org/10.4236/pp.2012.33047
https://doi.org/10.4236/pp.2012.33047
Autor:
José Agustín Quincoces Suárez, Paulo Celso Pardi, Amarilis Scremin Paulino, Carina Rodrigues, Fernanda Faião Flores, Sérgio de Mendonça, Susana Nogueira Diniz, Niraldo Paulino, Ivair D. Gonçalves, Reginaldo Pereira Santos
Publikováno v:
Bioorganicmedicinal chemistry. 24(8)
This work describes the anti-inflammatory effect of the curcumin-analog compound, sodium 4-[5-(4-hydroxy-3-methoxyphenyl)-3-oxo-penta-1,4-dienyl]-2-methoxy-phenolate (DM1), and shows that DM1 modulates iNOS and COX-2 gene expression in cultured RAW 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce8655756b97e0d83b4d4ca14a3ff83a
https://pubmed.ncbi.nlm.nih.gov/27010501
https://pubmed.ncbi.nlm.nih.gov/27010501
Autor:
Helmut Reinke, Manfred Michalik, Klaus Peseke, José Agustín Quincoces Suárez, Iran Otero Martinez, Reinaldo Molina Ruiz
Publikováno v:
Journal of Carbohydrate Chemistry. 23:337-351
Isopropyl 6‐O‐acetyl‐3‐deoxy‐4‐S‐ethyl‐4‐thio‐α‐D‐threo‐hexopyranosid‐2‐ulose (3) was converted to the corresponding 3‐[bis(methylthio)methylene] derivative 4 with a push–pull activated C–C double bond. Treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cd0262c76ad5bef9a57cabb9999a862
https://doi.org/10.1081/car-200035744
https://doi.org/10.1081/car-200035744
Autor:
Lidcay Herrera Taboada, José Agustín Quincoces Suárez, Holger Feist, Klaus Peseke, Manfred Michalik
Publikováno v:
Journal of Carbohydrate Chemistry. 23:325-335
1‐(Methyl 3‐O‐benzyl‐4,6‐O‐benzylidene‐2‐deoxy‐α‐D‐altropyranosid‐2‐yl)‐4‐phenyl‐but‐3‐yn‐2‐one (4) was synthesized by the reaction of (methyl 3‐O‐benzyl‐4,6‐O‐benzylidene‐2‐deoxy‐α‐D‐altr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21dd43f6f900f876ef52aa52c6c926a2
https://doi.org/10.1081/car-200035736
https://doi.org/10.1081/car-200035736
Autor:
Mario Gomez Andreu, José Agustín Quincoces Suárez, Klaus Peseke, Helmut Reinke, Manfred Michalik
Publikováno v:
Journal für praktische Chemie. 342:389-395
The α-oxoketene dithioacetal 1 was demethylthiolated with sodium borohydride to give the branched chain anhydroulose 2 which yielded with amines the corresponding aminomethylene enuloses 3, 4 and 5. The heterocyclic anellated pyranose derivatives 6,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac6dc649ff6de511393a3de4e6e03d25
https://doi.org/10.1002/(sici)1521-3897(200004)342:4<389::aid-prac389>3.0.co
https://doi.org/10.1002/(sici)1521-3897(200004)342:4<389::aid-prac389>3.0.co