Zobrazeno 1 - 10
of 24
pro vyhledávání: '"José Adelaïde"'
Autor:
Alexandre deNonneville, Elsa Kalbacher, Francesco Cannone, Arnaud Guille, José Adelaïde, Pascal Finetti, Maria Cappiello, Eric Lambaudie, Giuseppe Ettore, Emmanuelle Charafe, Emilie Mamessier, Magali Provansal, François Bertucci, Renaud Sabatier
Publikováno v:
Molecular Oncology, Vol 18, Iss 10, Pp 2586-2600 (2024)
Endometrioid ovarian cancers (EOvC) are usually managed as serous tumors. In this study, we conducted a comprehensive molecular investigation to uncover the distinct biological characteristics of EOvC. This retrospective multicenter study involved pa
Externí odkaz:
https://doaj.org/article/7e6216ea4f234271b8862b530fe72449
Autor:
Renaud Sabatier, Cécile Vicier, Séverine Garnier, Arnaud Guille, Nadine Carbuccia, Nicolas Isambert, Florence Dalenc, Marie Robert, Christelle Levy, Jihane Pakradouni, José Adelaïde, Max Chaffanet, Patrick Sfumato, Emilie Mamessier, François Bertucci, Anthony Goncalves
Publikováno v:
Molecular Oncology, Vol 16, Iss 10, Pp 2057-2070 (2022)
The phosphatidylinositol‐3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway is frequently activated in HER2‐negative breast cancer and may play a role in taxane resistance. The phase IB/II TAKTIC trial (NCT01980277) has shown that
Externí odkaz:
https://doaj.org/article/703ca5faef324c5b808393f820024f09
Autor:
François Bertucci, Anthony Gonçalves, Arnaud Guille, José Adelaïde, Séverine Garnier, Nadine Carbuccia, Emilien Billon, Pascal Finetti, Patrick Sfumato, Audrey Monneur, Christophe Pécheux, Martin Khran, Serge Brunelle, Lenaïg Mescam, Jeanne Thomassin-Piana, Flora Poizat, Emmanuelle Charafe-Jauffret, Olivier Turrini, Eric Lambaudie, Magali Provansal, Jean-Marc Extra, Anne Madroszyk, Marine Gilabert, Renaud Sabatier, Cécile Vicier, Emilie Mamessier, Christian Chabannon, Jihane Pakradouni, Patrice Viens, Fabrice André, Gwenaelle Gravis, Cornel Popovici, Daniel Birnbaum, Max Chaffanet
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-20 (2021)
Abstract Background The benefit of precision medicine based on relatively limited gene sets and often-archived samples remains unproven. PERMED-01 (NCT02342158) was a prospective monocentric clinical trial assessing, in adults with advanced solid can
Externí odkaz:
https://doaj.org/article/685cee8dc4e4477fb464978bcebb91ff
Autor:
Emilie Mamessier, Joo Y. Song, Franziska C. Eberle, Svetlana Pack, Charlotte Drevet, Bruno Chetaille, Ziedulla Abdullaev, José Adelaïde, Daniel Birnbaum, Max Chaffanet, Stefania Pittaluga, Sandrine Roulland, Andreas Chott, Elaine S. Jaffe, Bertrand Nadel
Publikováno v:
Haematologica, Vol 99, Iss 3 (2014)
The pathogenesis of follicular lymphoma is a multi-hit process progressing over many years through the accumulation of numerous genetic alterations. Besides the hallmark t(14;18), it is still unclear which other oncogenic hits contribute to the early
Externí odkaz:
https://doaj.org/article/17e753079341453796457d448b87ad81
Autor:
Ismahane Bekhouche, Pascal Finetti, José Adelaïde, Anthony Ferrari, Carole Tarpin, Emmanuelle Charafe-Jauffret, Colette Charpin, Gilles Houvenaeghel, Jocelyne Jacquemier, Ghislain Bidaut, Daniel Birnbaum, Patrice Viens, Max Chaffanet, François Bertucci
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e16950 (2011)
BackgroundInflammatory breast cancer (IBC) is an aggressive form of BC poorly defined at the molecular level. We compared the molecular portraits of 63 IBC and 134 non-IBC (nIBC) clinical samples.Methodology/findingsGenomic imbalances of 49 IBCs and
Externí odkaz:
https://doaj.org/article/a1bf4a75764545508643eb38080c3f9e
Autor:
François Bertucci, Florence Lerebours, Michele Ceccarelli, Arnaud Guille, Najeeb Syed, Pascal Finetti, José Adélaïde, Steven Van Laere, Anthony Goncalves, Patrice Viens, Daniel Birnbaum, Emilie Mamessier, Céline Callens, Davide Bedognetti
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract Background Inflammatory breast cancer (IBC) is the most pro-metastatic form of BC. Better understanding of its enigmatic pathophysiology is crucial. We report here the largest whole-exome sequencing (WES) study of clinical IBC samples. Metho
Externí odkaz:
https://doaj.org/article/d411209f682649f3b4011eb089a7cbba
Autor:
Elsa Nigon, Claudia Lefeuvre-Plesse, Alejandra Martinez, Céline Chauleur, Alain Lortholary, Laure Favier, Anne-Sophie Bats, Arnaud Guille, José AdélaÏde, Pascal Finetti, Victoire de Casteljac, Magali Provansal, Emilie Mamessier, François Bertucci, Isabelle Ray-Coquard, Renaud Sabatier
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Background Uterine clear cell carcinomas (CCC) represent less than 5% of uterine cancers. Their biological characteristics and clinical management remain uncertain. A multicenter study to explore both clinical and molecular features of these
Externí odkaz:
https://doaj.org/article/18beccffa9ee4428b18e4bd708adad27
Autor:
Nathalie Cervera, Arnaud Guille, José Adélaïde, Marie‐Anne Hospital, Sylvain Garciaz, Marie‐Joelle Mozziconacci, Norbert Vey, Véronique Gelsi‐Boyer, Daniel Birnbaum
Publikováno v:
eJHaem, Vol 4, Iss 2, Pp 450-453 (2023)
Abstract Acute erythroid leukemia (AEL) is a rare (2%–5%) form of acute myeloid leukemia (AML). Molecular alterations found in AEL resemble those of other AMLs. We report a classification of AELs in three major classes, with different prognosis and
Externí odkaz:
https://doaj.org/article/d6312bdd72cb46629c506d098c5d8cc2
Autor:
Carolina Velazquez, Esin Orhan, Imene Tabet, Lise Fenou, Béatrice Orsetti, José Adélaïde, Arnaud Guille, Simon Thézénas, Evelyne Crapez, Pierre-Emmanuel Colombo, Max Chaffanet, Daniel Birnbaum, Claude Sardet, William Jacot, Charles Theillet
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundAbout 15% of Triple-Negative-Breast-Cancer (TNBC) present silencing of the BRCA1 promoter methylation and are assumed to be Homologous Recombination Deficient (HRD). BRCA1-methylated (BRCA1-Me) TNBC could, thus, be eligible to treatment bas
Externí odkaz:
https://doaj.org/article/e04a4c983fe14d5c8fffd7f0ddb98082
Autor:
Violette Azzoni, Julien Wicinski, Manon Macario, Martin Castagné, Pascal Finetti, Katerina Ambrosova, Célia D. Rouault, Arnaud Sergé, Anne Farina, Emilie Agavnian, Sergiu Coslet, Emmanuelle Josselin, Arnaud Guille, José Adelaide, Emmanouil Zacharioudakis, Rémy Castellano, Francois Bertucci, Daniel Birnbaum, Raphael Rodriguez, Emmanuelle Charafe-Jauffret, Christophe Ginestier
Publikováno v:
Cell Death and Disease, Vol 13, Iss 2, Pp 1-15 (2022)
Abstract Replication stress (RS) has a pivotal role in tumor initiation, progression, or therapeutic resistance. In this study, we depicted the mechanism of breast cancer stem cells’ (bCSCs) response to RS and its clinical implication. We demonstra
Externí odkaz:
https://doaj.org/article/41f1ef2e00194644a397b32092889d81