Functional trajectories associated with acute illness and hospitalization in oldest old patients: Impact on mortality

Autor: Eva Gallego-González, Jennifer Mayordomo-Cava, María T. Vidán, María I. Valadés-Malagón, José A. Serra-Rexach, Javier Ortiz-Alonso

Publikováno v: Frontiers in Physiology, Vol 13 (2022)

Background: The literature pays low attention to functional changes during acute illness in older patients. Our main objectives were to separately describe the different functional changes occurring before and after hospital admission in oldest old m

Externí odkaz: https://doaj.org/article/ae95d2c002a64767b0fb5801710605bf

Epistasis, physical capacity-related genes and exceptional longevity: FNDC5 gene interactions with candidate genes FOXOA3 and APOE

Autor: Noriyuki Fuku, Roberto Díaz-Peña, Yasumichi Arai, Yukiko Abe, Hirofumi Zempo, Hisashi Naito, Haruka Murakami, Motohiko Miyachi, Carlos Spuch, José A. Serra-Rexach, Enzo Emanuele, Nobuyoshi Hirose, Alejandro Lucia

Publikováno v: BMC Genomics, Vol 18, Iss S8, Pp 125-131 (2017)

Abstract Background Forkhead box O3A (FOXOA3) and apolipoprotein E (APOE) are arguably the strongest gene candidates to influence human exceptional longevity (EL, i.e., being a centenarian), but inconsistency exists among cohorts. Epistasis, defined

Externí odkaz: https://doaj.org/article/735a4b2e956348c887ec0cd9c086af47

Recuperación funcional al alta y a tres meses tras una intervención multicomponente de ejercicio físico en ancianos hospitalizados en una unidad de agudos de geriatría

Autor: Cristina Carrasco Paniagua, Jennifer Mayordomo Cava, Teresa Zarralanga Lasobras, Sofía González Chávez, Javier Ortiz Alonso, José Antonio Serra Rexach

Publikováno v: Revista Española de Geriatría y Gerontología. 57:156-160

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2f6e1d934fbbb1317238e25080e6dc37
https://doi.org/10.1016/j.regg.2022.01.007

Current evidence on the impact of medication optimization or pharmacological interventions on frailty or aspects of frailty: a systematic review of randomized controlled trials

Autor: Alpana Mair, Jean-Baptiste Beuscart, Heidi Gruner, Wilma Knol, George Soulis, Peter Crome, Chakravarthi Rajkumar, Michael Denkinger, Nathalie van der Velde, Paul Gallaghar, Antonio Cherubini, Jennifer M. Stevenson, Farhad Pazan, Rob J. van Marum, Katarzyna Wieczorowska-Tobis, Martin Wehling, Tischa J. M. van der Cammen, Agnieszka Neumann-Podczaska, Marit Stordal Bakken, Gijsbertus Ziere, Alfonso J. Cruz-Jentoft, Adalsteinn Guðmundsson, Jean-Pierre Baeyens, Alberto Pilotto, Elina Rönnemaa, Kinda Ibrahim, Mirko Petrovic, Heinrich Burkhardt, Denis O'Mahony, Graziano Onder, Thomas Frühwald, José Antonio Serra-Rexach, Marilia Andreia Fernandes, Dhayana Dallmeier

Publikováno v: European Journal of Clinical Pharmacology
Pazan, F, Petrovic, M, Cherubini, A, Onder, G, Cruz-Jentoft, A J, Denkinger, M, van der Cammen, T J M, Stevenson, J M, Ibrahim, K, Rajkumar, C, Bakken, M S, Baeyens, J P, Crome, P, Frühwald, T, Gallaghar, P, Guðmundsson, A, Knol, W, O’Mahony, D, Pilotto, A, Rönnemaa, E, Serra-Rexach, J A, Soulis, G, van Marum, R J, Ziere, G, Mair, A, Burkhardt, H, Neumann-Podczaska, A, Wieczorowska-Tobis, K, Fernandes, M A, Gruner, H, Dallmeier, D, Beuscart, J B, van der Velde, N & Wehling, M 2021, ' Current evidence on the impact of medication optimization or pharmacological interventions on frailty or aspects of frailty : a systematic review of randomized controlled trials ', European Journal of Clinical Pharmacology, vol. 77, no. 1 . https://doi.org/10.1007/s00228-020-02951-8

Background Frailty and adverse drug effects are linked in the fact that polypharmacy is correlated with the severity of frailty; however, a causal relation has not been proven in older people with clinically manifest frailty. Methods A literature sea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79ade7d0461ff7d7aa2d3fe37fb765c4
https://doi.org/10.1007/s00228-020-02951-8

Geriatría transversal. Un reto asistencial para el siglo xxi

Autor: Myriam Rodríguez Couso, Francisco Javier Martín-Sánchez, Carmen Sánchez Castellano, Raquel Ramírez-Martín, Javier Gómez-Pavón, Teresa Alarcón, Pilar Sáez López, Maria Pi-Figueras Valls, Carlos Rodríguez-Pascual, Rocío Menéndez Colino, José Gutiérrez Rodríguez, Jose Luis Gonzalez Guerrero, Cristina Bermejo Boixareu, José Antonio Serra Rexach, Javier Martinez Peromingo, Francisco José Tarazona-Santabalbina, A. Vilches-Moraga, Francesc Formiga, Nicolás Martínez-Velilla, Ana Isabel Hormigo Sánchez, María T. Vidán, Juan Ignacio González-Montalvo

Publikováno v: Revista Española de Geriatría y Gerontología. 55:84-97

Resumen Cada vez es mayor el numero de pacientes de edad avanzada que esta siendo tratado por especialidades diferentes a la geriatria, las cuales, por las caracteristicas de sus tratamientos, necesitan conocer el pronostico que tiene su indicacion e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5f12eea1ff0785c1a10fca150b3d40ed
https://doi.org/10.1016/j.regg.2019.10.011