Zobrazeno 1 - 10
of 736
pro vyhledávání: '"José A. Sahel"'
Autor:
Alexandre Dentel, MD, Elena Brazhnikova, MD, Nathaniel Norberg, MSc, Céline Jaillard, PhD, Kate Grieve, PhD, Michel Paques, MD, PhD, José A. Sahel, MD, PhD, Stéphane Bertin, MD, Valérie Forster, MSc, Serge Picaud, PhD
Publikováno v:
Ophthalmology Science, Vol 3, Iss 4, Pp 100316- (2023)
Objective: To describe adaptive optics flood illumination ophthalmoscopy (AO-FIO) of the photoreceptor layer in normal nonhuman primates (NHPs) and in the case of a short-term induced retinal detachment (RD). Design: Longitudinal fundamental research
Externí odkaz:
https://doaj.org/article/bde445aa81b141f28d66182c94fe1d03
Autor:
David J. Calkins, Patrick Yu-Wai-Man, Nancy J. Newman, Magali Taiel, Pramila Singh, Clémentine Chalmey, Alexandra Rogue, Valerio Carelli, Philippe Ancian, José A. Sahel
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 23, Iss , Pp 307-318 (2021)
Lenadogene nolparvovec (Lumevoq) gene therapy was developed to treat Leber hereditary optic neuropathy (LHON) caused by the m.11778G > A in MT-ND4 that affects complex I of the mitochondrial respiratory chain. Lenadogene nolparvovec is a replication-
Externí odkaz:
https://doaj.org/article/7d8456c524ac4b3a9e71cc8d5f2d63e9
Autor:
Bogdan Kolomiets, Elisabeth Dubus, Manuel Simonutti, Serge Rosolen, José A. Sahel, Serge Picaud
Publikováno v:
Neurobiology of Disease, Vol 38, Iss 1, Pp 47-58 (2010)
Several strategies have been proposed to restore useful vision following photoreceptor degeneration. However, a very few studies have investigated late anatomical changes and functional state of residual retinal neurons after complete photoreceptor l
Externí odkaz:
https://doaj.org/article/e6d80f896a414800a535e81fea452d6a
Autor:
Marie Darche, Anna Verschueren, Morgane Belle, Leyna Boucherit, Stéphane Fouquet, José Alain Sahel, Alain Chédotal, Ilaria Cascone, Michel Paques
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-10 (2022)
An organic-solvent based clearing technique is used to visualize the vasculature in 3D using light sheet microscopy in retinal and hyaloid vessel development, and applied to branch retinal vein occlusion (BRVO) models.
Externí odkaz:
https://doaj.org/article/6c2a556e138a4d7b9b223cda3470cd5c
Autor:
Nancy J. Newman, Matthew Schniederjan, Pia R. Mendoza, David J. Calkins, Patrick Yu-Wai-Man, Valérie Biousse, Valerio Carelli, Magali Taiel, Francois Rugiero, Pramila Singh, Alexandra Rogue, José-Alain Sahel, Philippe Ancian
Publikováno v:
BMC Neurology, Vol 22, Iss 1, Pp 1-7 (2022)
Abstract Background Leber Hereditary Optic Neuropathy (LHON) is a rare, maternally-inherited mitochondrial disease that primarily affects retinal ganglion cells (RGCs) and their axons in the optic nerve, leading to irreversible, bilateral severe visi
Externí odkaz:
https://doaj.org/article/923f8af8163d42f2bf38d764929e4ab8
Autor:
Kassandra Groux, Anna Verschueren, Céline Nanteau, Marilou Clémençon, Mathias Fink, José-Alain Sahel, Claude Boccara, Michel Paques, Sacha Reichman, Kate Grieve
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-11 (2022)
Dynamic full-field optical coherence tomography (D-FFOCT) is used for live cell imaging of primary porcine retinal pigment epithelium (ppRPE) cultures and human induced pluripotent stem cell-derived RPE (hiRPE) cultures, allowing non-invasive realtim
Externí odkaz:
https://doaj.org/article/2d5649b8833b447b849efa3ccebc585d
Publikováno v:
Ophthalmology Science, Vol 2, Iss 3, Pp 100216- (2022)
Externí odkaz:
https://doaj.org/article/2e73614ea22e475485a88b5986bcb75f
Autor:
Bilge E Öztürk, Molly E Johnson, Michael Kleyman, Serhan Turunç, Jing He, Sara Jabalameli, Zhouhuan Xi, Meike Visel, Valérie L Dufour, Simone Iwabe, Luis Felipe L Pompeo Marinho, Gustavo D Aguirre, José-Alain Sahel, David V Schaffer, Andreas R Pfenning, John G Flannery, William A Beltran, William R Stauffer, Leah C Byrne
Publikováno v:
eLife, Vol 10 (2021)
Background: Adeno-associated virus (AAV)-mediated gene therapies are rapidly advancing to the clinic, and AAV engineering has resulted in vectors with increased ability to deliver therapeutic genes. Although the choice of vector is critical, quantita
Externí odkaz:
https://doaj.org/article/2f839da7c7b643a2acc12975971ae2e2
Autor:
Chafik Keilani, Edouard Augstburger, Mathieu Robin, Amélie Beaugrand, Raphaëlle Ores, José-Alain Sahel, Sarah Ayello-Scheer
Publikováno v:
Türk Oftalmoloji Dergisi, Vol 49, Iss 6, Pp 334-341 (2019)
Objectives:To compare biochemical outcomes, effectiveness, and tolerance of two high-density silicone oils (HDSOs), silicone oil- RMN3 (Oxane® HD) and silicone oil-Densiron-68 (Densiron® 68), for the management of complicated retinal detachment (RD
Externí odkaz:
https://doaj.org/article/a27f40a0b10d4793931a0ad9f0faa46b
Publikováno v:
Ophthalmology and Therapy, Vol 8, Iss 3, Pp 461-476 (2019)
Abstract Introduction The purpose of this study (Tilak Study No: TIL-001) was to evaluate the medical modules on the mobile medical application OdySight and compare them to the gold standard tests for visual acuity, contrast sensitivity, and Amsler G
Externí odkaz:
https://doaj.org/article/37727c8a99544316babc7904ea42d67f